STRINGSTRING
LOC106933844 LOC106933844 ccnd1 ccnd1 LOC106917157 LOC106917157 cdc27 cdc27 cul4b cul4b LOC106917323 LOC106917323 spdl1 spdl1 ccnb3 ccnb3 bub3 bub3 prkdc prkdc ENSPMEP00000000772 ENSPMEP00000000772 ENSPMEP00000000796 ENSPMEP00000000796 LOC106914516 LOC106914516 LOC106914501 LOC106914501 ndc80 ndc80 tm4sf5 tm4sf5 mblac1 mblac1 chek1 chek1 LOC106908950 LOC106908950 ENSPMEP00000002705 ENSPMEP00000002705 LOC106924292 LOC106924292 ENSPMEP00000003319 ENSPMEP00000003319 LOC106927616 LOC106927616 haspin haspin ENSPMEP00000003909 ENSPMEP00000003909 mad1l1 mad1l1 zfyve19 zfyve19 VPS4B VPS4B LOC106913923 LOC106913923 TFAP4 TFAP4 LOC106909763 LOC106909763 foxn3 foxn3 fbxo31 fbxo31 pla2g4a pla2g4a fhl1 fhl1 appl1 appl1 fbxo7 fbxo7 LOC106904372 LOC106904372 riok2 riok2 LOC106921954 LOC106921954 ambra1 ambra1 babam2 babam2 dtl dtl gen1 gen1 ENSPMEP00000007297 ENSPMEP00000007297 plk2 plk2 ENSPMEP00000007343 ENSPMEP00000007343 nop53 nop53 LOC106911190 LOC106911190 kank2 kank2 LOC106920242 LOC106920242 cdk1 cdk1 mad2l1bp mad2l1bp ddb1 ddb1 anapc7 anapc7 cdt1 cdt1 rgcc rgcc lcmt1 lcmt1 atad5 atad5 znf207 znf207 ENSPMEP00000010995 ENSPMEP00000010995 taok1 taok1 aven aven cul4a cul4a cdc16 cdc16 rint1 rint1 mre11 mre11 cdc23 cdc23 ctdsp2 ctdsp2 ENSPMEP00000012266 ENSPMEP00000012266 LOC106907130 LOC106907130 anapc4 anapc4 ccnd2 ccnd2 ints3 ints3 ENSPMEP00000012886 ENSPMEP00000012886 cdc73 cdc73 cdc25b cdc25b babam1 babam1 cdkn2c cdkn2c nsmce2 nsmce2 ttk ttk usp47 usp47 sass6 sass6 LOC106906387 LOC106906387 LOC106908594 LOC106908594 ticrr ticrr wac wac stox1 stox1 LSM11 LSM11 ENSPMEP00000014965 ENSPMEP00000014965 e2f7 e2f7 LOC106912892 LOC106912892 ENSPMEP00000015172 ENSPMEP00000015172 xrcc3 xrcc3 LOC106919335 LOC106919335 cpsf3 cpsf3 kmt2e kmt2e adam17 adam17 gnl3 gnl3 klhl22 klhl22 cdc7 cdc7 LOC106934012 LOC106934012 ENSPMEP00000016996 ENSPMEP00000016996 LOC106916031 LOC106916031 LOC106910011 LOC106910011 e2f1 e2f1 mfsd11 mfsd11 pinx1 pinx1 plrg1 plrg1 LOC106928455 LOC106928455 cdc14a cdc14a orc1 orc1 ube2c ube2c bcl7a bcl7a LOC106911739 LOC106911739 psme1 psme1 ino80 ino80 CPSF3 CPSF3 LOC106931379 LOC106931379 cdk5rap3 cdk5rap3 psme2 psme2 LOC106905489 LOC106905489 LOC106916628 LOC106916628 ENSPMEP00000019524 ENSPMEP00000019524 ENSPMEP00000019689 ENSPMEP00000019689 LOC106904790 LOC106904790 LOC106904789 LOC106904789 topbp1 topbp1 ZNF830 ZNF830 anapc11 anapc11 rptor rptor CTDSP1 CTDSP1 casp2 casp2 ecd ecd rb1 rb1 ENSPMEP00000021364 ENSPMEP00000021364 mad2l1 mad2l1 LOC106928197 LOC106928197 ercc2 ercc2 uimc1 uimc1 LOC106908319 LOC106908319 ccnh ccnh chfr chfr ENSPMEP00000022667 ENSPMEP00000022667 LOC106932944 LOC106932944 LOC106908261 LOC106908261 DONSON DONSON clspn clspn LOC106917807 LOC106917807 bcl2 bcl2 LOC106905240 LOC106905240 tfap4 tfap4 cdc26 cdc26 ENSPMEP00000024512 ENSPMEP00000024512 LOC106926957 LOC106926957 LOC106912263 LOC106912263 LOC106933565 LOC106933565 gpnmb gpnmb plk3 plk3 xpc xpc cdkn2d cdkn2d ENSPMEP00000025754 ENSPMEP00000025754 LSM10 LSM10 FZR1 FZR1 AIF1 AIF1 LOC106926881 LOC106926881 nbn nbn CUL3 CUL3 pidd1 pidd1 ENSPMEP00000027840 ENSPMEP00000027840 ENSPMEP00000027881 ENSPMEP00000027881 atm atm zwilch zwilch pkd1 pkd1 rbl1 rbl1 LOC106922832 LOC106922832 LOC106929963 LOC106929963 mnat1 mnat1 blm blm taok3 taok3 miip miip prmt2 prmt2 rad51c rad51c cdc6 cdc6 LOC106924007 LOC106924007 LOC106931254 LOC106931254 anapc5 anapc5 mtbp mtbp taok2 taok2 LOC106930587 LOC106930587 kntc1 kntc1 appl2 appl2 ENSPMEP00000031568 ENSPMEP00000031568 kif14 kif14 ENSPMEP00000031827 ENSPMEP00000031827 rfwd3 rfwd3 LOC106922589 LOC106922589 PLK1 PLK1 dcun1d3 dcun1d3 brd7 brd7 brca1 brca1 ENSPMEP00000033181 ENSPMEP00000033181 anapc15 anapc15 crlf3 crlf3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LOC106933844F-box protein 5. (418 aa)
ccnd1Cyclin D1; Belongs to the cyclin family. (292 aa)
LOC106917157Cyclin-dependent kinase inhibitor 1Bb. (194 aa)
cdc27Cell division cycle 27. (803 aa)
cul4bCullin 4B; Belongs to the cullin family. (868 aa)
LOC106917323Uncharacterized protein. (216 aa)
spdl1Protein Spindly; Required for the localization of dynein and dynactin to the mitotic kintochore. Dynein is believed to control the initial lateral interaction between the kinetochore and spindle microtubules and to facilitate the subsequent formation of end-on kinetochore-microtubule attachments mediated by the NDC80 complex; Belongs to the Spindly family. (574 aa)
ccnb3Cyclin B3; Belongs to the cyclin family. (430 aa)
bub3BUB3 mitotic checkpoint protein. (326 aa)
prkdcProtein kinase, DNA-activated, catalytic subunit; Belongs to the PI3/PI4-kinase family. (4020 aa)
ENSPMEP00000000772Raptor_N domain-containing protein. (85 aa)
ENSPMEP00000000796RAD17 checkpoint clamp loader component. (531 aa)
LOC106914516G protein-coupled receptor 132a; Belongs to the G-protein coupled receptor 1 family. (352 aa)
LOC106914501Uncharacterized protein. (593 aa)
ndc80NDC80 kinetochore complex component. (640 aa)
tm4sf5Zgc:172079. (203 aa)
mblac1Metallo-beta-lactamase domain containing 1. (216 aa)
chek1Checkpoint kinase 1; Belongs to the protein kinase superfamily. (455 aa)
LOC106908950Zw10 kinetochore protein. (619 aa)
ENSPMEP00000002705Reverse transcriptase domain-containing protein. (1016 aa)
LOC106924292Cyclin-dependent kinase inhibitor 1A. (153 aa)
ENSPMEP00000003319Uncharacterized protein. (570 aa)
LOC106927616TAO kinase 1a. (1013 aa)
haspinSi:dkeyp-26a9.2. (1201 aa)
ENSPMEP00000003909Cell division cycle associated 5. (274 aa)
mad1l1Mitotic arrest deficient 1 like 1. (719 aa)
zfyve19Zinc finger, FYVE domain containing 19. (425 aa)
VPS4BVacuolar protein sorting 4 homolog B; Belongs to the AAA ATPase family. (508 aa)
LOC106913923BUB1 mitotic checkpoint serine/threonine kinase Bb. (428 aa)
TFAP4BHLH domain-containing protein. (336 aa)
LOC106909763Methyl CpG binding protein 2. (997 aa)
foxn3Checkpoint suppressor 1. (485 aa)
fbxo31F-box protein 31. (585 aa)
pla2g4aPhospholipase A2. (749 aa)
fhl1Four and a half LIM domains 1a. (297 aa)
appl1Adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1. (708 aa)
fbxo7F-box protein 7. (458 aa)
LOC106904372WW domain-containing protein. (478 aa)
riok2RIO kinase 2 (yeast). (519 aa)
LOC106921954Retinoblastoma-like 2 (p130). (1066 aa)
ambra1Autophagy/beclin-1 regulator 1b. (1201 aa)
babam2BRISC and BRCA1 A complex member 2. (379 aa)
dtlDenticleless E3 ubiquitin protein ligase homolog (Drosophila). (651 aa)
gen1Chromo_2 domain-containing protein. (642 aa)
ENSPMEP00000007297Uncharacterized protein. (216 aa)
plk2Serine/threonine-protein kinase PLK. (657 aa)
ENSPMEP00000007343TAO kinase 3b. (422 aa)
nop53Ribosome biogenesis protein NOP53; May play a role in ribosome biogenesis. Belongs to the NOP53 family. (466 aa)
LOC106911190Nucleic acid binding protein 1a. (221 aa)
kank2KN motif and ankyrin repeat domains 2. (1011 aa)
LOC106920242Uncharacterized protein. (553 aa)
cdk1Cyclin-dependent kinase 1; Belongs to the protein kinase superfamily. (302 aa)
mad2l1bpMAD2L1 binding protein. (365 aa)
ddb1Damage-specific DNA binding protein 1. (1139 aa)
anapc7Anaphase promoting complex subunit 7. (565 aa)
cdt1Chromatin licensing and DNA replication factor 1. (650 aa)
rgccRegulator of cell cycle. (121 aa)
lcmt1Leucine carboxyl methyltransferase 1; Methylates the carboxyl group of the C-terminal leucine residue of protein phosphatase 2A catalytic subunits to form alpha- leucine ester residues; Belongs to the methyltransferase superfamily. LCMT family. (325 aa)
atad5AAA domain-containing protein. (825 aa)
znf207Zinc finger protein 207, b. (440 aa)
ENSPMEP00000010995Uncharacterized protein. (230 aa)
taok1TAO kinase 1b. (1015 aa)
avenApoptosis, caspase activation inhibitor. (314 aa)
cul4aCullin 4A; Belongs to the cullin family. (646 aa)
cdc16Cell division cycle 16 homolog (S. cerevisiae). (618 aa)
rint1RAD50 interactor 1. (788 aa)
mre11Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing. (692 aa)
cdc23CDC23 (cell division cycle 23, yeast, homolog). (575 aa)
ctdsp2CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 2. (263 aa)
ENSPMEP00000012266Abraxas 1, BRCA1 A complex subunit. (318 aa)
LOC106907130Uncharacterized protein. (185 aa)
anapc4Anaphase-promoting complex subunit 4; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. Belongs to the APC4 family. (802 aa)
ccnd2Cyclin D2, b; Belongs to the cyclin family. (330 aa)
ints3Integrator complex subunit 3. (1019 aa)
ENSPMEP00000012886Reverse transcriptase domain-containing protein. (861 aa)
cdc73Cell division cycle 73, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae). (530 aa)
cdc25bRhodanese domain-containing protein. (563 aa)
babam1BRISC and BRCA1 A complex member 1. (382 aa)
cdkn2cANK_REP_REGION domain-containing protein. (161 aa)
nsmce2NSE2 (MMS21) homolog, SMC5-SMC6 complex SUMO ligase. (230 aa)
ttkTtk protein kinase. (996 aa)
usp47Ubiquitin specific peptidase 47; Belongs to the peptidase C19 family. (1358 aa)
sass6Sas6_CC domain-containing protein. (473 aa)
LOC106906387Uncharacterized protein; Belongs to the AAA ATPase family. (435 aa)
LOC106908594FCP1 homology domain-containing protein. (351 aa)
ticrrTreslin_N domain-containing protein. (1465 aa)
wacWW domain containing adaptor with coiled-coil a. (543 aa)
stox1Storkhead box 1. (1086 aa)
LSM11LSM11, U7 small nuclear RNA associated. (228 aa)
ENSPMEP00000014965Reverse transcriptase domain-containing protein. (1039 aa)
e2f7E2F transcription factor 7. (799 aa)
LOC106912892U7 snRNA-associated Sm-like protein LSm11. (228 aa)
ENSPMEP00000015172Uncharacterized protein. (201 aa)
xrcc3DNA repair protein; Involved in the homologous recombination repair (HRR) pathway of double-stranded DNA, thought to repair chromosomal fragmentation, translocations and deletions; Belongs to the RecA family. RAD51 subfamily. (348 aa)
LOC106919335Cyclin-dependent kinase inhibitor 2A/B (p15, inhibits CDK4). (124 aa)
cpsf3Cleavage and polyadenylation specific factor 3. (690 aa)
kmt2eLysine (K)-specific methyltransferase 2E. (1204 aa)
adam17ADAM metallopeptidase domain 17b. (841 aa)
gnl3Guanine nucleotide binding protein-like 3 (nucleolar). (527 aa)
klhl22Kelch-like family member 22. (632 aa)
cdc7Cell division cycle 7 homolog (S. cerevisiae). (609 aa)
LOC106934012ATPase family AAA domain containing 5a. (1813 aa)
ENSPMEP00000016996Uncharacterized protein. (153 aa)
LOC106916031Checkpoint protein; Belongs to the HUS1 family. (285 aa)
LOC106910011Cyclin D2, a; Belongs to the cyclin family. (296 aa)
e2f1E2F transcription factor 1. (456 aa)
mfsd11Major facilitator superfamily domain containing 11. (454 aa)
pinx1PIN2 (TERF1) interacting telomerase inhibitor 1. (363 aa)
plrg1Pleiotropic regulator 1. (513 aa)
LOC106928455Vacuolar protein sorting 4 homolog A; Belongs to the AAA ATPase family. (436 aa)
cdc14aCell division cycle 14Ab. (591 aa)
orc1Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. (913 aa)
ube2cUbiquitin-conjugating enzyme E2C; Belongs to the ubiquitin-conjugating enzyme family. (174 aa)
bcl7aBAF chromatin remodeling complex subunit BCL7A. (199 aa)
LOC106911739CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like b. (273 aa)
psme1Proteasome activator subunit 1. (253 aa)
ino80INO80 complex ATPase subunit. (1038 aa)
CPSF3Beta-Casp domain-containing protein. (254 aa)
LOC106931379CULLIN_2 domain-containing protein; Belongs to the cullin family. (767 aa)
cdk5rap3CDK5 regulatory subunit associated protein 3. (506 aa)
psme2Proteasome activator subunit 2. (245 aa)
LOC106905489Aurora kinase B; Belongs to the protein kinase superfamily. (331 aa)
LOC106916628Cyclin-dependent kinase inhibitor 1D. (179 aa)
ENSPMEP00000019524Uncharacterized protein. (167 aa)
ENSPMEP00000019689CDK5 regulatory subunit associated protein 2. (1112 aa)
LOC106904790Si:ch211-137i24.10. (191 aa)
LOC106904789Si:ch211-137i24.10. (192 aa)
topbp1DNA topoisomerase II binding protein 1. (1515 aa)
ZNF830Zinc finger protein 830. (335 aa)
anapc11APC11 anaphase promoting complex subunit 11 homolog (yeast). (84 aa)
rptorRegulatory associated protein of MTOR, complex 1. (1294 aa)
CTDSP1CTD small phosphatase 1. (306 aa)
casp2Caspase 2, apoptosis-related cysteine peptidase; Belongs to the peptidase C14A family. (444 aa)
ecdEcdysoneless homolog (Drosophila). (661 aa)
rb1Retinoblastoma 1. (913 aa)
ENSPMEP00000021364Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (219 aa)
mad2l1MAD2 mitotic arrest deficient-like 1 (yeast). (236 aa)
LOC106928197Cyclin-dependent kinase inhibitor 1-like. (153 aa)
ercc2Excision repair cross-complementation group 2. (739 aa)
uimc1Uncharacterized protein. (918 aa)
LOC106908319Uncharacterized protein. (485 aa)
ccnhCyclin H; Belongs to the cyclin family. (319 aa)
chfrCheckpoint with forkhead and ring finger domains, E3 ubiquitin protein ligase. (627 aa)
ENSPMEP00000022667Reverse transcriptase domain-containing protein. (297 aa)
LOC106932944Aurora kinase B-like. (331 aa)
LOC106908261Vacuolar protein sorting-associated protein 4A. (436 aa)
DONSONDownstream neighbor of SON. (586 aa)
clspnUncharacterized protein. (859 aa)
LOC106917807Translocated promoter region a, nuclear basket protein. (2082 aa)
bcl2BCL2 apoptosis regulator b. (229 aa)
LOC106905240CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like a. (268 aa)
tfap4Transcription factor AP-4 (activating enhancer binding protein 4). (329 aa)
cdc26Cell division cycle 26 homolog. (94 aa)
ENSPMEP00000024512Protein kinase domain-containing protein. (109 aa)
LOC106926957CTD small phosphatase-like protein. (273 aa)
LOC106912263NOP53 ribosome biogenesis factor. (322 aa)
LOC106933565Uncharacterized protein. (446 aa)
gpnmbGlycoprotein (transmembrane) nmb. (606 aa)
plk3Serine/threonine-protein kinase PLK. (667 aa)
xpcXeroderma pigmentosum, complementation group C. (930 aa)
cdkn2dCyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4). (164 aa)
ENSPMEP00000025754Uncharacterized protein. (93 aa)
LSM10LSM10, U7 small nuclear RNA associated. (115 aa)
FZR1Fizzy/cell division cycle 20 related 1a. (497 aa)
AIF1Allograft inflammatory factor 1. (147 aa)
LOC106926881ADAM metallopeptidase domain 17a. (859 aa)
nbnNibrin. (843 aa)
CUL3Cullin 3; Belongs to the cullin family. (766 aa)
pidd1P53-induced death domain protein 1. (913 aa)
ENSPMEP00000027840Uncharacterized protein. (73 aa)
ENSPMEP00000027881CENP-F_N domain-containing protein. (78 aa)
atmNon-specific serine/threonine protein kinase. (3013 aa)
zwilchZwilch kinetochore protein. (594 aa)
pkd1Polycystic kidney disease 1a. (4429 aa)
rbl1Retinoblastoma-like 1 (p107). (1055 aa)
LOC106922832Fizzy/cell division cycle 20 related 1b. (487 aa)
LOC106929963Translocated promoter region b, nuclear basket protein. (1688 aa)
mnat1CDK-activating kinase assembly factor MAT1; Stabilizes the cyclin H-CDK7 complex to form a functional CDK-activating kinase (CAK) enzymatic complex. (311 aa)
blmBLM RecQ like helicase. (1396 aa)
taok3TAO kinase 3a. (901 aa)
miipMigration and invasion inhibitory protein. (395 aa)
prmt2Protein arginine methyltransferase 2; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. (463 aa)
rad51cRAD51 paralog C. (357 aa)
cdc6Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family. (637 aa)
LOC106924007Transmembrane 4 L six family member 5. (214 aa)
LOC106931254Four and a half LIM domains 1b. (280 aa)
anapc5Anaphase promoting complex subunit 5. (804 aa)
mtbpMDM2 binding protein. (875 aa)
taok2Protein kinase domain-containing protein. (1173 aa)
LOC106930587SOSS complex subunit B2-like. (221 aa)
kntc1Kinetochore associated 1. (1921 aa)
appl2Adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2. (665 aa)
ENSPMEP00000031568Zgc:158343. (144 aa)
kif14Kinesin family member 14; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1621 aa)
ENSPMEP00000031827Protein kinase domain-containing protein. (154 aa)
rfwd3Ring finger and WD repeat domain 3. (711 aa)
LOC106922589STIL centriolar assembly protein. (1058 aa)
PLK1Serine/threonine-protein kinase PLK. (592 aa)
dcun1d3DCN1-like protein. (318 aa)
brd7Bromodomain containing 7. (618 aa)
brca1Uncharacterized protein. (1316 aa)
ENSPMEP00000033181Lactamase_B domain-containing protein. (145 aa)
anapc15Anaphase promoting complex subunit 15. (122 aa)
crlf3Cytokine receptor-like factor 3. (445 aa)
Your Current Organism:
Poecilia mexicana
NCBI taxonomy Id: 48701
Other names: shortfin molly
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