STRINGSTRING
ADE40756.1 ADE40756.1 ADE40493.1 ADE40493.1 rpmE rpmE ADE40541.1 ADE40541.1 ADE40568.1 ADE40568.1 ADE40598.1 ADE40598.1 ADE40612.1 ADE40612.1 rplJ rplJ rplL rplL rpsG rpsG rpsJ rpsJ rplC rplC rplD rplD rplW rplW rplB rplB rpsS rpsS rplV rplV rpsC rpsC rplP rplP rpmC rpmC rpsQ rpsQ rplN rplN rplX rplX rplE rplE rpsN rpsN rpsH rpsH rplF rplF rplR rplR rpsE rpsE rpmD rpmD rplO rplO rpsK rpsK rplQ rplQ ADE40660.1 ADE40660.1 guaB guaB ADE38248.1 ADE38248.1 rpmF rpmF ADE38344.1 ADE38344.1 ADE38352.1 ADE38352.1 ADE38368.1 ADE38368.1 ADE38372.1 ADE38372.1 ADE38416.1 ADE38416.1 ADE38419.1 ADE38419.1 ADE38424.1 ADE38424.1 ADE38505.1 ADE38505.1 ADE38541.1 ADE38541.1 ADE38731.1 ADE38731.1 rpsI rpsI rplM rplM rpsB rpsB recO recO ADE38793.1 ADE38793.1 rpmG rpmG ADE38867.1 ADE38867.1 rpsF rpsF rpsR rpsR rplI rplI ADE38888.1 ADE38888.1 ADE38909.1 ADE38909.1 rpsD rpsD ADE38933.1 ADE38933.1 ADE38992.1 ADE38992.1 ADE39294.1 ADE39294.1 ADE39317.1 ADE39317.1 smc smc rpmI rpmI ADE39495.1 ADE39495.1 ADE39496.1 ADE39496.1 ADE39535.1 ADE39535.1 ADE39536.1 ADE39536.1 ADE39549.1 ADE39549.1 ADE39550.1 ADE39550.1 ADE39551.1 ADE39551.1 rpsU rpsU ADE39607.1 ADE39607.1 ADE39635.1 ADE39635.1 ADE39678.1 ADE39678.1 ADE39733.1 ADE39733.1 recR recR ADE39777.1 ADE39777.1 ADE39778.1 ADE39778.1 recF recF dnaA dnaA rpsT rpsT rpsO rpsO infB infB nth nth dnaQ dnaQ ADE39892.1 ADE39892.1 ADE39904.1 ADE39904.1 ADE39910.1 ADE39910.1 ADE39993.1 ADE39993.1 ADE39994.1 ADE39994.1 ADE40044.1 ADE40044.1 rpsP rpsP priA priA rpmA rpmA rplU rplU ADE40102.1 ADE40102.1 ADE40755.1 ADE40755.1 ADE40114.1 ADE40114.1 rpmB rpmB ADE40150.1 ADE40150.1 edd edd ADE40371.1 ADE40371.1 rplY rplY dnaG dnaG
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ADE40756.1Methyltransferase type 11. (219 aa)
ADE40493.1Hypothetical protein. (145 aa)
rpmERibosomal protein L31; Binds the 23S rRNA; Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily. (100 aa)
ADE40541.1Periplasmic protein TonB, links inner and outer membranes. (331 aa)
ADE40568.1ATPase involved in DNA repair; May be involved in recombinational repair of damaged DNA. (553 aa)
ADE40598.1Hypothetical protein. (127 aa)
ADE40612.1Short-chain dehydrogenase/reductase SDR. (227 aa)
rplJRibosomal protein L10; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the universal ribosomal protein uL10 family. (189 aa)
rplL50S ribosomal protein L7/L12; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation; Belongs to the bacterial ribosomal protein bL12 family. (126 aa)
rpsGRibosomal protein S7; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA; Belongs to the universal ribosomal protein uS7 family. (156 aa)
rpsJRibosomal protein S10; Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family. (102 aa)
rplC50S ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit. (275 aa)
rplD50S ribosomal protein L4; Forms part of the polypeptide exit tunnel. (258 aa)
rplWRibosomal protein L25/L23; One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome; Belongs to the universal ribosomal protein uL23 family. (108 aa)
rplBRibosomal protein L2; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family. (274 aa)
rpsSRibosomal protein S19; Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA. (91 aa)
rplVRibosomal protein L22; The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome. (125 aa)
rpsCRibosomal protein S3; Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation; Belongs to the universal ribosomal protein uS3 family. (231 aa)
rplPRibosomal protein L16; Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs; Belongs to the universal ribosomal protein uL16 family. (139 aa)
rpmCRibosomal protein L29; Belongs to the universal ribosomal protein uL29 family. (71 aa)
rpsQRibosomal protein S17; One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA. (81 aa)
rplNRibosomal protein L14; Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome; Belongs to the universal ribosomal protein uL14 family. (122 aa)
rplXRibosomal protein L24; One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit. (105 aa)
rplERibosomal protein L5; This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs. (181 aa)
rpsN30S ribosomal protein S14; Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site; Belongs to the universal ribosomal protein uS14 family. (101 aa)
rpsHRibosomal protein S8; One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; Belongs to the universal ribosomal protein uS8 family. (132 aa)
rplFRibosomal protein L6; This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center; Belongs to the universal ribosomal protein uL6 family. (177 aa)
rplRRibosomal protein L18; This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. (120 aa)
rpsERibosomal protein S5; Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body. Belongs to the universal ribosomal protein uS5 family. (189 aa)
rpmDRibosomal protein L30. (61 aa)
rplORibosomal protein L15; Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family. (157 aa)
rpsKRibosomal protein S11; Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine- Dalgarno cleft in the 70S ribosome; Belongs to the universal ribosomal protein uS11 family. (131 aa)
rplQRibosomal protein L17. (144 aa)
ADE40660.1ATPase related to the helicase subunit of the Holliday junction resolvase. (463 aa)
guaBInosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. (506 aa)
ADE38248.1Hypothetical protein. (263 aa)
rpmFRibosomal protein L32; Belongs to the bacterial ribosomal protein bL32 family. (65 aa)
ADE38344.1Superfamily II DNA and RNA helicase; Belongs to the DEAD box helicase family. (464 aa)
ADE38352.1Hypothetical protein. (261 aa)
ADE38368.1Histone family protein DNA-binding protein; Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions. (91 aa)
ADE38372.1Molecular chaperone; Belongs to the small heat shock protein (HSP20) family. (150 aa)
ADE38416.1Integration host factor, alpha subunit; This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control. Belongs to the bacterial histone-like protein family. (97 aa)
ADE38419.1AAA ATPase. (615 aa)
ADE38424.1Hypothetical protein. (1130 aa)
ADE38505.1Class II aldolase/adducin family protein. (263 aa)
ADE38541.1Selenium-binding protein, putative. (451 aa)
ADE38731.1Glutathione-dependent formaldehyde-activating, GFA. (121 aa)
rpsIRibosomal protein S9; Belongs to the universal ribosomal protein uS9 family. (193 aa)
rplMRibosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. (155 aa)
rpsBRibosomal protein S2; Belongs to the universal ribosomal protein uS2 family. (287 aa)
recODNA repair protein RecO; Involved in DNA repair and RecF pathway recombination. (250 aa)
ADE38793.1Ribosomal subunit interface protein, putative. (208 aa)
rpmGRibosomal protein L33; Belongs to the bacterial ribosomal protein bL33 family. (55 aa)
ADE38867.1Hypothetical protein; Belongs to the DnaA family. (228 aa)
rpsFRibosomal protein S6; Binds together with S18 to 16S ribosomal RNA. (146 aa)
rpsRRibosomal protein S18; Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit; Belongs to the bacterial ribosomal protein bS18 family. (84 aa)
rplI50S ribosomal protein L9; Binds to the 23S rRNA. (218 aa)
ADE38888.1Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins. Belongs to the helicase family. DnaB subfamily. (499 aa)
ADE38909.1DNA repair protein RadC; Belongs to the UPF0758 family. (247 aa)
rpsDRibosomal protein S4:RNA-binding S4:Ribosomal protein S4, bacterial and organelle form; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit. (208 aa)
ADE38933.1Protein of unknown function DUF159; Belongs to the SOS response-associated peptidase family. (222 aa)
ADE38992.1Glutathione-dependent formaldehyde-activating, GFA. (120 aa)
ADE39294.1Glutathione-dependent formaldehyde-activating GFA. (142 aa)
ADE39317.1Helicase domain protein. (991 aa)
smcChromosome segregation ATPase; Required for chromosome condensation and partitioning. Belongs to the SMC family. (1132 aa)
rpmIHypothetical protein; Belongs to the bacterial ribosomal protein bL35 family. (65 aa)
ADE39495.1Ribosomal protein S1; Binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence. (565 aa)
ADE39496.1Integration host factor, beta subunit; This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control. Belongs to the bacterial histone-like protein family. (92 aa)
ADE39535.1Hypothetical protein. (206 aa)
ADE39536.1UvrD/REP helicase. (914 aa)
ADE39549.1TPR repeat protein. (768 aa)
ADE39550.1Tetratricopeptide repeat family protein. (468 aa)
ADE39551.1TPR repeat protein. (584 aa)
rpsURibosomal protein S21; Belongs to the bacterial ribosomal protein bS21 family. (67 aa)
ADE39607.1Putative DEAD box ATP-dependent RNA helicase protein. (651 aa)
ADE39635.1Hypothetical protein. (244 aa)
ADE39678.1Hypothetical protein. (182 aa)
ADE39733.1Conserved hypothetical protein TIGR00103; Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection. (107 aa)
recRRecombination protein RecR; May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO. (197 aa)
ADE39777.1Putative TPR repeat protein. (734 aa)
ADE39778.1Putative metallophosphoesterase. (350 aa)
recFRecF protein; The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP. (418 aa)
dnaAATPase; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. Belongs to the DnaA family. (510 aa)
rpsTRibosomal protein S20p; Binds directly to 16S ribosomal RNA. (88 aa)
rpsOSSU ribosomal protein S15P; Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome. (89 aa)
infBTranslation initiation factor 2; One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily. (867 aa)
nthPredicted EndoIII-related endonuclease; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate. (214 aa)
dnaQDNA polymerase III, epsilon subunit and related 3'-5' exonuclease; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'- 5' exonuclease. (255 aa)
ADE39892.1parB-like partition protein; Belongs to the ParB family. (361 aa)
ADE39904.1TPR repeat protein. (594 aa)
ADE39910.1DNA methylase N-4/N-6; Belongs to the N(4)/N(6)-methyltransferase family. (363 aa)
ADE39993.1Hypothetical protein. (341 aa)
ADE39994.1TrwC protein. (1018 aa)
ADE40044.1Peptidase S16, lon-like protein. (217 aa)
rpsPRibosomal protein S16; Belongs to the bacterial ribosomal protein bS16 family. (201 aa)
priAPrimosomal protein N' (replication factor Y) - superfamily II helicase; Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA; Belongs to the helicase family. PriA subfamily. (755 aa)
rpmARibosomal protein L27; Belongs to the bacterial ribosomal protein bL27 family. (89 aa)
rplURibosomal protein L21; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family. (170 aa)
ADE40102.1Hypothetical membrane associated protein. (166 aa)
ADE40755.1Putative sirtuin. (254 aa)
ADE40114.1Hypothetical protein; Belongs to the Cob(I)alamin adenosyltransferase family. (194 aa)
rpmBLSU ribosomal protein L28P; Belongs to the bacterial ribosomal protein bL28 family. (95 aa)
ADE40150.1CobS protein. (335 aa)
edd6-phosphogluconate dehydratase; Catalyzes the dehydration of 6-phospho-D-gluconate to 2- dehydro-3-deoxy-6-phospho-D-gluconate; Belongs to the IlvD/Edd family. (609 aa)
ADE40371.1Phytoene dehydrogenase. (510 aa)
rplY50S ribosomal protein L25; This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance. Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily. (211 aa)
dnaGDNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. (560 aa)
Your Current Organism:
Puniceispirillum marinum
NCBI taxonomy Id: 488538
Other names: C. Puniceispirillum marinum IMCC1322, Candidatus Puniceispirillum marinum IMCC1322, Candidatus Puniceispirillum marinum str. IMCC1322, Candidatus Puniceispirillum marinum strain IMCC1322, alpha proteobacterium IMCC1322
Server load: low (24%) [HD]