STRINGSTRING
EFC57576.1 EFC57576.1 EFC57577.1 EFC57577.1 speE speE speD speD rimK rimK EFC57944.1 EFC57944.1 potF potF potA-2 potA-2 EFC57947.1 EFC57947.1 EFC57948.1 EFC57948.1 EFC57949.1 EFC57949.1 rumB rumB EFC58099.1 EFC58099.1 EFC58100.1 EFC58100.1 puuR puuR puuD puuD glnA glnA EFC58111.1 EFC58111.1 EFC58112.1 EFC58112.1 EFC58114.1 EFC58114.1 EFC58115.1 EFC58115.1 EFC58116.1 EFC58116.1 EFC58117.1 EFC58117.1 potD potD potC potC potB potB potA potA EFC57170.1 EFC57170.1 pepT pepT EFC57172.1 EFC57172.1 EFC56743.1 EFC56743.1 EFC56744.1 EFC56744.1 EFC56745.1 EFC56745.1 EFC56746.1 EFC56746.1 EFC56747.1 EFC56747.1 EFC56793.1 EFC56793.1 EFC56794.1 EFC56794.1 EFC56795.1 EFC56795.1 EFC56796.1 EFC56796.1 EFC56797.1 EFC56797.1 EFC56577.1 EFC56577.1 EFC56578.1 EFC56578.1 EFC56579.1 EFC56579.1 mtnK mtnK mtnA mtnA mtnD mtnD mtnC mtnC mtnB mtnB EFC55458.1 EFC55458.1 potE potE SpeF SpeF EFC55536.1 EFC55536.1 speB speB speA speA EFC53965.1 EFC53965.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
EFC57576.1Glyoxalase family protein; KEGG: chu:CHU_2533 6.4e-44 gloA; lactoylglutathione lyase K08234; Psort location: Cytoplasmic, score: 8.96. (129 aa)
EFC57577.1Orn/Lys/Arg decarboxylase, major domain protein; KEGG: ent:Ent638_0724 0. L-lysine decarboxylase K01582. (710 aa)
speESpermidine synthase; Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine. (289 aa)
speDS-adenosylmethionine decarboxylase proenzyme; Catalyzes the decarboxylation of S-adenosylmethionine to S- adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine; Belongs to the prokaryotic AdoMetDC family. Type 2 subfamily. (264 aa)
rimKalpha-L-glutamate ligase, RimK family; KEGG: noc:Noc_1549 1.3e-102 S6 modification enzyme RimK K05844; Psort location: Cytoplasmic, score: 8.96; Belongs to the RimK family. (315 aa)
EFC57944.1Hypothetical protein. (158 aa)
potFPutrescine-binding periplasmic protein; Required for the activity of the bacterial periplasmic transport system of putrescine; Belongs to the bacterial solute-binding protein PotD/PotF family. (370 aa)
potA-2Polyamine ABC transporter, ATP-binding protein; Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system. (391 aa)
EFC57947.1ABC transporter, permease protein; KEGG: cag:Cagg_2347 1.0e-12 ornithine carbamoyltransferase K11070; Psort location: CytoplasmicMembrane, score: 10.00. (295 aa)
EFC57948.1ABC transporter, permease protein; KEGG: ecl:EcolC_2739 1.2e-136 ornithine carbamoyltransferase K11074; Psort location: CytoplasmicMembrane, score: 10.00. (281 aa)
EFC57949.1Hypothetical protein; Psort location: CytoplasmicMembrane, score: 9.46. (138 aa)
rumB23S rRNA (uracil-5-)-methyltransferase RumB; Catalyzes the formation of 5-methyl-uridine at position 747 (m5U747) in 23S rRNA; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. RlmC subfamily. (375 aa)
EFC58099.1FAD dependent oxidoreductase; KEGG: kpn:KPN_01017 7.4e-217 oxidoreductase; K09471 gamma-glutamylputrescine oxidase; Psort location: Cytoplasmic, score: 8.96. (426 aa)
EFC58100.1Aldehyde dehydrogenase (NAD) family protein; KEGG: kpn:KPN_01018 2.9e-231 gamma-glutamyl-gamma-aminobutyraldehyde dehydrogenase; K09472 gamma-glutamyl-gamma-aminobutyraldehyde dehydrogenase; Psort location: Cytoplasmic, score: 9.97. (495 aa)
puuRHTH-type transcriptional regulator PuuR; KEGG: psp:PSPPH_2917 7.4e-11 DNA-binding protein K00517; Psort location: Cytoplasmic, score: 8.96. (185 aa)
puuDKEGG: kpe:KPK_3540 3.9e-124 puuD; gamma-glutamyl-gamma-aminobutyrate hydrolase K09473; Psort location: Cytoplasmic, score: 8.96. (254 aa)
glnAGlutamate--ammonia ligase, catalytic domain protein; KEGG: kpn:KPN_01021 4.0e-241 putative glutamine synthetase; K09470 gamma-glutamylputrescine synthase; Psort location: Cytoplasmic, score: 9.97. (472 aa)
EFC58111.1Putative membrane protein; Psort location: CytoplasmicMembrane, score: 10.00. (305 aa)
EFC58112.1Hypothetical protein. (39 aa)
EFC58114.1KEGG: ara:Arad_8144 1.0e-187 dhaL; aldehyde dehydrogenase protein; K09472 gamma-glutamyl-gamma-aminobutyraldehyde dehydrogenase; Psort location: Cytoplasmic, score: 9.26. (499 aa)
EFC58115.1Transcriptional regulator, GntR family; Psort location: Cytoplasmic, score: 8.96. (225 aa)
EFC58116.1FAD dependent oxidoreductase; KEGG: rso:RSc2113 6.1e-142 putative oxidoreductase protein K00540. (387 aa)
EFC58117.1SNARE-like domain protein; KEGG: hha:Hhal_0736 1.5e-07 alkaline phosphatase; K01077 alkaline phosphatase; Psort location: CytoplasmicMembrane, score: 9.46. (167 aa)
potDSpermidine/putrescine ABC transporter periplasmic substrate-binding protein; Required for the activity of the bacterial periplasmic transport system of putrescine; Belongs to the bacterial solute-binding protein PotD/PotF family. (344 aa)
potCSpermidine/putrescine ABC transporter, permease protein PotC; KEGG: ecl:EcolC_2479 5.5e-125 ornithine carbamoyltransferase K11070; Psort location: CytoplasmicMembrane, score: 10.00. (263 aa)
potBSpermidine/putrescine ABC transporter membrane protein; KEGG: rca:Rcas_2838 1.4e-15 ornithine carbamoyltransferase K11070; Psort location: CytoplasmicMembrane, score: 10.00. (285 aa)
potAPutrescine/spermidine ABC transporter ATPase protein; Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system. (275 aa)
EFC57170.1Hypothetical protein. (75 aa)
pepTPeptidase T; Cleaves the N-terminal amino acid of tripeptides. Belongs to the peptidase M20B family. (421 aa)
EFC57172.1Hypothetical protein. (163 aa)
EFC56743.1N-acetyltransferase; KEGG: ent:Ent638_2068 2.4e-138 N-hydroxyarylamine O-acetyltransferase K00675; Psort location: Cytoplasmic, score: 8.96; Belongs to the arylamine N-acetyltransferase family. (281 aa)
EFC56744.1ABC transporter, permease protein; KEGG: mmw:Mmwyl1_3520 1.6e-17 ornithine carbamoyltransferase K11074; Psort location: CytoplasmicMembrane, score: 10.00. (547 aa)
EFC56745.1ABC transporter, solute-binding protein; KEGG: hiq:CGSHiGG_03235 1.5e-21 fbpC; ferric transporter ATP-binding subunit K02012; Psort location: Periplasmic, score: 9.44. (322 aa)
EFC56746.1KEGG: bpa:BPP2628 5.5e-54 ABC transport protein, ATP-binding component; K02010 iron(III) transport system ATP-binding protein; Psort location: Cytoplasmic, score: 9.12. (230 aa)
EFC56747.1Flavin reductase-like protein; KEGG: tro:trd_A0738 0.00078 nitrilotriacetate monooxygenase component B (NTA monooxygenase component B) (NtA-MO B). (190 aa)
EFC56793.1ABC transporter, permease protein; KEGG: bwe:BcerKBAB4_1203 1.5e-37 ornithine carbamoyltransferase K11070; Psort location: CytoplasmicMembrane, score: 10.00. (268 aa)
EFC56794.1ABC transporter, permease protein; KEGG: rca:Rcas_2838 1.7e-13 ornithine carbamoyltransferase K11070; Psort location: CytoplasmicMembrane, score: 10.00. (319 aa)
EFC56795.1TOBE domain protein; KEGG: pen:PSEEN1241 1.7e-27 ABC transporter, ATP-binding protein K02052. (137 aa)
EFC56796.1KEGG: pen:PSEEN1241 8.9e-70 ABC transporter, ATP-binding protein K02052. (196 aa)
EFC56797.1ABC transporter, solute-binding protein; Psort location: Periplasmic, score: 9.44. (381 aa)
EFC56577.1Hypothetical protein; Psort location: Cytoplasmic, score: 8.96. (41 aa)
EFC56578.12,4-diaminobutyrate 4-transaminase; KEGG: ent:Ent638_2713 3.0e-236 diaminobutyrate--2-oxoglutarate aminotransferase K00836; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (458 aa)
EFC56579.1Pyridoxal-dependent decarboxylase domain protein; KEGG: eta:ETA_04470 2.6e-221 ddc; L-2,4-diaminobutyrate decarboxylase. (488 aa)
mtnKS-methyl-5-thioribose kinase; Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate. (399 aa)
mtnAS-methyl-5-thioribose-1-phosphate isomerase; Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). (338 aa)
mtnDAcireductone dioxygenase (Ni(2+)-requiring); Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway. (180 aa)
mtnC2,3-diketo-5-methylthio-1-phosphopentane phosphatase; Bifunctional enzyme that catalyzes the enolization of 2,3- diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK- MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene). Belongs to the HAD-like hydrolase superfamily. MasA/MtnC family. (229 aa)
mtnBMethylthioribulose-1-phosphate dehydratase; Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P). Belongs to the aldolase class II family. MtnB subfamily. (204 aa)
EFC55458.1KEGG: ent:Ent638_1144 1.2e-191 putative aminotransferase K10907. (386 aa)
potEPutrescine-ornithine antiporter; Catalyzes both the uptake and excretion of putrescine. The uptake of putrescine is dependent on the membrane potential and the excretion involves putrescine-ornithine antiporter activity. Belongs to the amino acid-polyamine-organocation (APC) superfamily. Basic amino acid/polyamine antiporter (APA) (TC 2.A.3.2) family. (437 aa)
SpeFOrn/Lys/Arg decarboxylase, major domain protein; KEGG: ent:Ent638_1205 0. ornithine decarboxylase K01581; Psort location: Cytoplasmic, score: 8.96. (732 aa)
EFC55536.1Hypothetical protein. (74 aa)
speBAgmatinase; KEGG: ect:ECIAI39_3356 2.5e-152 speB; agmatinase K01480; Psort location: Cytoplasmic, score: 8.96; Belongs to the arginase family. (283 aa)
speAArginine 2-monooxygenase; Catalyzes the biosynthesis of agmatine from arginine. (637 aa)
EFC53965.1Orn/Lys/Arg decarboxylase, major domain protein; KEGG: ent:Ent638_3380 0. ornithine decarboxylase K01581. (728 aa)
Your Current Organism:
Enterobacter cancerogenus
NCBI taxonomy Id: 500639
Other names: E. cancerogenus ATCC 35316, Enterobacter cancerogenus ATCC 35316, Enterobacter cancerogenus str. ATCC 35316, Enterobacter cancerogenus strain ATCC 35316
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