STRINGSTRING
ilvN ilvN ilvB ilvB EFC57847.1 EFC57847.1 EFC57912.1 EFC57912.1 pflB pflB gabT gabT EFC57478.1 EFC57478.1 paaC paaC EFC57039.1 EFC57039.1 nifJ nifJ EFC56985.1 EFC56985.1 EFC56461.1 EFC56461.1 fadJ fadJ budA budA alsS alsS budC budC sdhC sdhC sdhD sdhD sdhA sdhA sQR sQR ilvB-2 ilvB-2 ilvN-2 ilvN-2 gabT-2 gabT-2 EFC54555.1 EFC54555.1 EFC54341.1 EFC54341.1 pflB-2 pflB-2 GabD GabD frdD frdD frdC frdC frdB frdB frdA frdA EFC53638.1 EFC53638.1 ilvB-3 ilvB-3 EFC53537.1 EFC53537.1 fadB fadB
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ilvNAcetolactate synthase, small subunit; KEGG: ent:Ent638_0625 1.0e-77 ilvH; acetolactate synthase 3 regulatory subunit K01653; Psort location: Cytoplasmic, score: 8.96. (163 aa)
ilvBAcetolactate synthase, large subunit, biosynthetic type; KEGG: ent:Ent638_0624 8.6e-294 acetolactate synthase 3 catalytic subunit K01652. (574 aa)
EFC57847.1Aldehyde dehydrogenase (NAD) family protein; KEGG: kpn:KPN_04772 1.3e-219 putative aldehyde dehydrogenase; K00135 succinate-semialdehyde dehydrogenase (NADP+); Psort location: Cytoplasmic, score: 9.97. (456 aa)
EFC57912.1KEGG: ent:Ent638_1317 0. pyruvate formate-lyase K00656; Psort location: Cytoplasmic, score: 9.97. (810 aa)
pflBFormate C-acetyltransferase; KEGG: cko:CKO_02168 0. hypothetical protein; K00656 formate C-acetyltransferase; Psort location: Cytoplasmic, score: 9.97. (760 aa)
gabT4-aminobutyrate transaminase; KEGG: ecr:ECIAI1_1327 1.6e-182 puuE; GabA aminotransferase, PLP-dependent; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (401 aa)
EFC57478.1enoyl-CoA hydratase/isomerase family protein; KEGG: ecj:JW1388 4.0e-106 paaF; enoyl-CoA hydratase-isomerase; K01692 enoyl-CoA hydratase; Psort location: Cytoplasmic, score: 8.96; Belongs to the enoyl-CoA hydratase/isomerase family. (255 aa)
paaC3-hydroxyacyl-CoA dehydrogenase PaaC; KEGG: ecj:JW1390 1.7e-203 paaH; 3-hydroxybutyryl-CoA dehydrogenase; K00074 3-hydroxybutyryl-CoA dehydrogenase. (475 aa)
EFC57039.1Aldehyde dehydrogenase (NAD) family protein; KEGG: ent:Ent638_2005 1.4e-213 aldehyde dehydrogenase; K08324 aldehyde dehydrogenase family protein; Psort location: Cytoplasmic, score: 9.26. (462 aa)
nifJKEGG: ent:Ent638_2136 0. pyruvate flavodoxin/ferredoxin oxidoreductase domain-containing protein; K03737 putative pyruvate-flavodoxin oxidoreductase. (1174 aa)
EFC56985.1Aldehyde dehydrogenase (NAD) family protein; KEGG: sek:SSPA1048 0. alcohol dehydrogenase; K00001 alcohol dehydrogenase K04072; Psort location: Cytoplasmic, score: 9.26; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family. (892 aa)
EFC56461.1KEGG: ent:Ent638_2558 0. flavocytochrome c; K00244 fumarate reductase flavoprotein subunit. (926 aa)
fadJFatty oxidation complex, alpha subunit FadJ; Catalyzes the formation of a hydroxyacyl-CoA by addition of water on enoyl-CoA. Also exhibits 3-hydroxyacyl-CoA epimerase and 3- hydroxyacyl-CoA dehydrogenase activities; In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family. (715 aa)
budAKEGG: ent:Ent638_2026 1.3e-132 acetolactate decarboxylase K01575; Psort location: Cytoplasmic, score: 8.96; Belongs to the alpha-acetolactate decarboxylase family. (260 aa)
alsSAcetolactate synthase, catabolic; KEGG: ent:Ent638_2027 2.8e-272 acetolactate synthase K01652; Psort location: CytoplasmicMembrane, score: 9.82; Belongs to the TPP enzyme family. (544 aa)
budCDiacetyl reductase ((R)-acetoin forming); KEGG: ent:Ent638_2028 2.0e-129 acetoin reductase; K03366 acetoin dehydrogenase; Psort location: Cytoplasmic, score: 9.26; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (264 aa)
sdhCKEGG: ecm:EcSMS35_0734 1.0e-61 sdhC; succinate dehydrogenase, cytochrome b556 subunit; K00241 succinate dehydrogenase cytochrome b-556 subunit; Psort location: CytoplasmicMembrane, score: 10.00. (134 aa)
sdhDSuccinate dehydrogenase, hydrophobic membrane anchor protein; Membrane-anchoring subunit of succinate dehydrogenase (SDH). (115 aa)
sdhAKEGG: ent:Ent638_1224 0. sdhA; succinate dehydrogenase flavoprotein subunit K00239; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily. (588 aa)
sQRKEGG: ent:Ent638_1225 1.0e-125 sdhB; succinate dehydrogenase iron-sulfur subunit K00240; Psort location: Cytoplasmic, score: 8.96; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family. (238 aa)
ilvB-2Acetolactate synthase, large subunit, biosynthetic type; KEGG: ent:Ent638_0025 3.0e-284 acetolactate synthase catalytic subunit K01652. (562 aa)
ilvN-2KEGG: ent:Ent638_0026 2.1e-45 acetolactate synthase 1 regulatory subunit K01653; Psort location: Cytoplasmic, score: 8.96. (95 aa)
gabT-2KEGG: ent:Ent638_3864 2.5e-207 4-aminobutyrate aminotransferase K00823; Psort location: Cytoplasmic, score: 8.96; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (432 aa)
EFC54555.1KEGG: ent:Ent638_3299 5.1e-193 acetyl-CoA acetyltransferase K00626; Psort location: Cytoplasmic, score: 9.97; Belongs to the thiolase-like superfamily. Thiolase family. (392 aa)
EFC54341.1Thiamine pyrophosphate enzyme, C-terminal TPP binding domain protein; KEGG: kpn:KPN_03360 1.3e-256 hypothetical protein; K01652 acetolactate synthase I/II/III large subunit; Belongs to the TPP enzyme family. (546 aa)
pflB-2KEGG: ent:Ent638_3561 0. keto acid formate lyase K00656; Psort location: Cytoplasmic, score: 9.97. (764 aa)
GabDKEGG: ent:Ent638_3676 2.5e-239 succinate semialdehyde dehydrogenase K00135; Psort location: Cytoplasmic, score: 9.26. (484 aa)
frdDFumarate reductase 13 kDa hydrophobic protein; KEGG: ent:Ent638_0340 2.7e-45 fumarate reductase subunit D K00247; Psort location: CytoplasmicMembrane, score: 10.00. (97 aa)
frdCFumarate reductase subunit C; Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane. (132 aa)
frdBKEGG: ent:Ent638_0342 4.4e-132 fumarate reductase iron-sulfur subunit K00245; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family. (244 aa)
frdAKEGG: cko:CKO_03678 0. fumarate reductase flavoprotein subunit; K00244 fumarate reductase flavoprotein subunit; Psort location: Periplasmic, score: 9.44. (596 aa)
EFC53638.1Phosphogluconate dehydrogenase (decarboxylating), NAD binding domain protein; Reduces 3-sulfolactaldehyde (SLA) to 2,3-dihydroxypropane 1- sulfonate (DHPS); Belongs to the HIBADH-related family. 3-sulfolactaldehyde reductase subfamily. (296 aa)
ilvB-3Acetolactate synthase, large subunit, biosynthetic type; KEGG: cko:CKO_00107 7.0e-276 acetolactate synthase 2 catalytic subunit; K01652 acetolactate synthase I/II/III large subunit; Psort location: Cytoplasmic, score: 8.96. (548 aa)
EFC53537.1KEGG: ent:Ent638_4014 1.0e-38 ilvM; acetolactate synthase 2 regulatory subunit K11258. (87 aa)
fadBFatty oxidation complex, alpha subunit FadB; Involved in the aerobic and anaerobic degradation of long- chain fatty acids via beta-oxidation cycle. Catalyzes the formation of 3-oxoacyl-CoA from enoyl-CoA via L-3-hydroxyacyl-CoA. It can also use D-3-hydroxyacyl-CoA and cis-3-enoyl-CoA as substrate. In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family. (729 aa)
Your Current Organism:
Enterobacter cancerogenus
NCBI taxonomy Id: 500639
Other names: E. cancerogenus ATCC 35316, Enterobacter cancerogenus ATCC 35316, Enterobacter cancerogenus str. ATCC 35316, Enterobacter cancerogenus strain ATCC 35316
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