STRINGSTRING
PADG_02414 PADG_02414 PADG_00803 PADG_00803 PADG_00872 PADG_00872 PADG_00873 PADG_00873 PADG_02804 PADG_02804 PADG_04791 PADG_04791 PADG_05571 PADG_05571 PADG_05610 PADG_05610 PADG_05825 PADG_05825 PADG_05906 PADG_05906 PADG_05907 PADG_05907 PADG_06001 PADG_06001 PADG_06095 PADG_06095 PADG_07134 PADG_07134
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PADG_02414Histone H2A.Z; Belongs to the histone H2A family. (404 aa)
PADG_00803DUF2236 domain-containing protein. (469 aa)
PADG_00872Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (142 aa)
PADG_00873Histone H3. (136 aa)
PADG_02804Uncharacterized protein. (287 aa)
PADG_04791Histone H3-like centromeric protein CSE4. (177 aa)
PADG_05571Uncharacterized protein. (96 aa)
PADG_05610Histone-lysine N-methyltransferase, H3 lysine-79 specific; Histone methyltransferase that specifically methylates histone H3 to form H3K79me. This methylation is required for telomere silencing and for the pachytene checkpoint during the meiotic cell cycle by allowing the recruitment of RAD9 to double strand breaks. Nucleosomes are preferred as substrate compared to free histones. (530 aa)
PADG_05825Uncharacterized protein. (164 aa)
PADG_05906Histone H2A; Belongs to the histone H2A family. (134 aa)
PADG_05907Histone H2B; Belongs to the histone H2B family. (141 aa)
PADG_06001H15 domain-containing protein. (203 aa)
PADG_06095CENP-T_C domain-containing protein. (465 aa)
PADG_07134Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (148 aa)
Your Current Organism:
Paracoccidioides brasiliensis
NCBI taxonomy Id: 502780
Other names: P. brasiliensis Pb18, Paracoccidioides brasiliensis Pb18
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