STRINGSTRING
EEF69740.1 EEF69740.1 EEF69696.1 EEF69696.1 EEF69579.1 EEF69579.1 EEF69598.1 EEF69598.1 EEF69565.1 EEF69565.1 EEF69283.1 EEF69283.1 glyA glyA EEF68871.1 EEF68871.1 kbl kbl serS serS EEF68761.1 EEF68761.1 EEF68677.1 EEF68677.1 proC proC EEF68614.1 EEF68614.1 folD folD EEF68426.1 EEF68426.1 aroB aroB aroC aroC aroK aroK EEF68432.1 EEF68432.1 EEF68368.1 EEF68368.1 EEF68315.1 EEF68315.1 EEF68317.1 EEF68317.1 EEF68289.1 EEF68289.1 EEF68226.1 EEF68226.1 EEF68233.1 EEF68233.1 carA carA carB carB carB-2 carB-2 EEF68158.1 EEF68158.1 EEF68159.1 EEF68159.1 aroQ aroQ tagD tagD EEF68100.1 EEF68100.1 EEF67862.1 EEF67862.1 EEF67805.1 EEF67805.1 EEF67787.1 EEF67787.1 EEF67750.1 EEF67750.1 dapB dapB EEF67672.1 EEF67672.1 alr alr dapD dapD dapF dapF asd asd EEF67373.1 EEF67373.1 EEF67299.1 EEF67299.1 EEF67274.1 EEF67274.1 EEF67262.1 EEF67262.1 pdxB-2 pdxB-2 serC serC EEF67196.1 EEF67196.1 EEF66966.1 EEF66966.1 dapA dapA EEF66741.1 EEF66741.1 asnA asnA EEF66561.1 EEF66561.1 EEF66544.1 EEF66544.1 mtnN mtnN EEF66501.1 EEF66501.1 gltA gltA folA folA EEF66344.1 EEF66344.1 thrB thrB EEF66287.1 EEF66287.1 EEF66288.1 EEF66288.1 asd-2 asd-2 mtnN-2 mtnN-2 EEF66078.1 EEF66078.1 EEF66022.1 EEF66022.1 alr-2 alr-2 EEF65897.1 EEF65897.1 EEF65843.1 EEF65843.1 EEF65832.1 EEF65832.1 EEF65813.1 EEF65813.1 EEF65814.1 EEF65814.1 EEF65740.1 EEF65740.1 EEF65745.1 EEF65745.1 EEF65703.1 EEF65703.1 EEF65600.1 EEF65600.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
EEF69740.1N-acetylglucosaminylphosphatidylinositol deacetylase; Psort location: Cytoplasmic, score: 8.87. (226 aa)
EEF69696.1Hypothetical protein; KEGG: sme:SMc03938 0.0016 pntB; probable NAD(P) transhydrogenase subunit beta transmembrane protein K00325; Psort location: CytoplasmicMembrane, score: 9.99. (203 aa)
EEF69579.1Hypothetical protein; Psort location: CytoplasmicMembrane, score: 9.99. (210 aa)
EEF69598.1Histidinol phosphate phosphatase HisJ family; KEGG: oih:OB0554 2.3e-45 histidinol phosphatase K04486; Psort location: Cytoplasmic, score: 8.87; Belongs to the PHP hydrolase family. HisK subfamily. (289 aa)
EEF69565.1KEGG: reh:H16_A1802 0.0073 acetyltransferase (GNAT) family K00680; Psort location: Cytoplasmic, score: 8.87. (250 aa)
EEF69283.1Putative diaminopropionate ammonia-lyase; KEGG: ppr:PBPRA1993 6.6e-80 putative threonine dehydratase; Psort location: Cytoplasmic, score: 8.87. (402 aa)
glyAGlycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (409 aa)
EEF68871.1Hypothetical protein; Psort location: Cytoplasmic, score: 8.87. (220 aa)
kblGlycine C-acetyltransferase; Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA. (397 aa)
serSserine--tRNA ligase; KEGG: mhu:Mhun_2507 6.7e-87 seryl-tRNA synthetase K01875; Psort location: Cytoplasmic, score: 10.00. (427 aa)
EEF68761.1Hypothetical protein; Psort location: CytoplasmicMembrane, score: 9.99. (229 aa)
EEF68677.1Hypothetical protein. (63 aa)
proCPyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. (261 aa)
EEF68614.1Hypothetical protein; KEGG: syc:syc1742_c 0.00055 murI; glutamate racemase K01776; Psort location: Cytoplasmic, score: 8.87. (219 aa)
folDTetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain protein; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. (284 aa)
EEF68426.1KEGG: ttj:TTHA1104 1.1e-47 prephenate dehydratase K04518; Psort location: Cytoplasmic, score: 9.98. (281 aa)
aroB3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ). (334 aa)
aroCChorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. (397 aa)
aroKShikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. (410 aa)
EEF68432.1Putative 3-deoxy-7-phosphoheptulonate synthase; KEGG: cpe:CPE0694 1.8e-38 phospho-2-dehydro-3-deoxyheptonate aldolase K03856; Psort location: Cytoplasmic, score: 8.87. (158 aa)
EEF68368.1KEGG: pha:PSHAa0252 0.0053 murI; glutamate racemase K01776; Psort location: Cytoplasmic, score: 8.87. (220 aa)
EEF68315.1Acetyltransferase, GNAT family; KEGG: gvi:glr3142 2.2e-24 putative acetyltransferase K03830. (156 aa)
EEF68317.1Peptidase dimerization domain protein; KEGG: bld:BLi02571 5.1e-19 yqjE; similar to tripeptidase; RBL01653 K01269; Psort location: Cytoplasmic, score: 8.87. (377 aa)
EEF68289.1Arylsulfatase; KEGG: btl:BALH_4730 2.2e-30 sulfatase; Psort location: CytoplasmicMembrane, score: 9.97. (626 aa)
EEF68226.1Amidohydrolase; KEGG: syn:slr1653 3.5e-58 ama; N-acyl-L-amino acid amidohydrolase K01436; Psort location: Cytoplasmic, score: 8.87. (366 aa)
EEF68233.1KEGG: hpa:HPAG1_0538 1.3e-05 acyl carrier protein K01162; Psort location: Cytoplasmic, score: 8.87. (75 aa)
carAKEGG: gka:GK1151 1.2e-96 carbamoyl-phosphate synthase(glutamine-hydrolyzing) small chain K01956; Psort location: Cytoplasmic, score: 8.87; Belongs to the CarA family. (361 aa)
carBKEGG: ljo:LJ1276 2.2e-127 carbamoylphosphate synthase large subunit K01955; Psort location: Cytoplasmic, score: 8.87. (329 aa)
carB-2Carbamoyl-phosphate synthetase, large subunit, oligomerization domain protein; KEGG: bca:BCE_3931 3.1e-217 carB; carbamoyl-phosphate synthase, large subunit K01955; Psort location: Cytoplasmic, score: 9.98; Belongs to the CarB family. (729 aa)
EEF68158.1Hypothetical protein; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. (156 aa)
EEF68159.1KEGG: cno:NT01CX_0626 2.1e-51 prephenate dehydrogenase K00210; Psort location: Cytoplasmic, score: 8.87. (282 aa)
aroQ3-dehydroquinate dehydratase, type II; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family. (147 aa)
tagDKEGG: bcl:ABC3101 9.1e-51 tagD; glycerol-3-phosphate cytidylyltransferase K00980; Psort location: Cytoplasmic, score: 9.98. (130 aa)
EEF68100.1Nucleotide sugar dehydrogenase; KEGG: spr:spr0318 3.4e-170 cps2K; UDPglucose 6-dehydrogenase K00012. (409 aa)
EEF67862.1Histidinol phosphate phosphatase HisJ family; KEGG: tte:TTE2610 1.0e-26 his2.2; histidinol phosphatase and related hydrolases of the PHP family K04486; Psort location: Cytoplasmic, score: 8.87. (269 aa)
EEF67805.1Nucleotide sugar dehydrogenase; KEGG: spr:spr0318 5.6e-170 cps2K; UDPglucose 6-dehydrogenase K00012. (418 aa)
EEF67787.1Glycosyltransferase, group 2 family protein; KEGG: tth:TTC0528 3.7e-31 rfbF; dTDP-rhamnosyl transferase RfbF. (322 aa)
EEF67750.1KEGG: hpa:HPAG1_0538 2.0e-07 acyl carrier protein K01162; Psort location: Cytoplasmic, score: 8.87. (75 aa)
dapBDihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate. (256 aa)
EEF67672.1KEGG: cpe:CPE0698 7.6e-15 chorismate mutase K04516; Psort location: Cytoplasmic, score: 8.87. (143 aa)
alrAlanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. (607 aa)
dapD2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-acetyltransferase; Catalyzes the transfer of an acetyl group from acetyl-CoA to tetrahydrodipicolinate. (232 aa)
dapFDiaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. (269 aa)
asdAspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. (333 aa)
EEF67373.1Hypothetical protein. (275 aa)
EEF67299.1Arylsulfatase; KEGG: btl:BALH_4730 2.0e-41 sulfatase; Psort location: CytoplasmicMembrane, score: 9.99. (588 aa)
EEF67274.1MBOAT family protein; KEGG: hne:HNE_2072 9.1e-67 algI; alginate biosynthesis protein AlgI K00680; Psort location: CytoplasmicMembrane, score: 9.99; Belongs to the membrane-bound acyltransferase family. (461 aa)
EEF67262.1Nucleotide sugar dehydrogenase; KEGG: spr:spr0318 4.8e-148 cps2K; UDPglucose 6-dehydrogenase K00012. (416 aa)
pdxB-24-phosphoerythronate dehydrogenase; KEGG: tbd:Tbd_0950 1.6e-101 D-isomer specific 2-hydroxyacid dehydrogenase K00058; Psort location: Cytoplasmic, score: 9.98. (387 aa)
serCPhosphoserine transaminase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine. (370 aa)
EEF67196.1Putative 3-deoxy-7-phosphoheptulonate synthase; KEGG: cac:CAC0892 4.3e-37 phospho-2-dehydro-3-deoxyheptonate aldolase K03856; Psort location: Cytoplasmic, score: 8.87. (158 aa)
EEF66966.1Oxidoreductase. (145 aa)
dapADihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). (290 aa)
EEF66741.1Acetyltransferase, GNAT family; KEGG: syn:sll1647 0.0036 putative acyltransferase K03823; Psort location: Cytoplasmic, score: 8.87. (198 aa)
asnAAspartate--ammonia ligase; KEGG: cpf:CPF_2233 6.3e-107 asnA; aspartate--ammonia ligase K01914; Psort location: Cytoplasmic, score: 10.00. (341 aa)
EEF66561.1Hypothetical protein. (60 aa)
EEF66544.1Hypothetical protein. (62 aa)
mtnNMTA/SAH nucleosidase; Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'- methylthioribose and S-ribosylhomocysteine, respectively. Belongs to the PNP/UDP phosphorylase family. MtnN subfamily. (235 aa)
EEF66501.1Putative isocitrate dehydrogenase, NAD-dependent; KEGG: bba:Bd1264 1.9e-98 leuB; 3-isopropylmalate dehydrogenase K00052; Psort location: Cytoplasmic, score: 9.98. (332 aa)
gltAKEGG: tte:TTE0567 5.5e-131 gltD; NADPH-dependent glutamate synthase beta chain and related oxidoreductases K00266; Psort location: Cytoplasmic, score: 9.98. (458 aa)
folAKEGG: son:SO3646 2.0e-23 folA; dihydrofolate reductase K00287; Psort location: Cytoplasmic, score: 8.87. (157 aa)
EEF66344.1Putative asparagine synthase (glutamine-hydrolyzing); KEGG: bcl:ABC1768 9.8e-102 asnO; asparagine synthetase, glutamine-hydrolyzing K01953; Psort location: Cytoplasmic, score: 8.87. (589 aa)
thrBHomoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily. (297 aa)
EEF66287.1KEGG: ldb:Ldb1350 5.3e-55 homoserine dehydrogenase K00003; Psort location: Cytoplasmic, score: 8.87. (405 aa)
EEF66288.1Amino acid kinase family; KEGG: ldb:Ldb1349 2.8e-120 ask; aspartate kinase K00928; Psort location: Cytoplasmic, score: 8.87; Belongs to the aspartokinase family. (445 aa)
asd-2Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. (334 aa)
mtnN-2MTA/SAH nucleosidase; Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'- methylthioribose and S-ribosylhomocysteine, respectively. Belongs to the PNP/UDP phosphorylase family. MtnN subfamily. (230 aa)
EEF66078.1Amino acid kinase family; KEGG: bca:BCE_3837 3.1e-41 dapG; aspartate kinase I K00928; Psort location: Cytoplasmic, score: 8.87. (248 aa)
EEF66022.1Hypothetical protein; Psort location: Cytoplasmic, score: 8.87. (361 aa)
alr-2Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. (371 aa)
EEF65897.1Acetyltransferase, GNAT family; KEGG: eci:UTI89_C4688 3.0e-20 phnO; putative regulator, phn operon K00680; Psort location: Cytoplasmic, score: 8.87. (148 aa)
EEF65843.1N-acetylglucosaminylphosphatidylinositol deacetylase; KEGG: pgi:PG1285 2.6e-05 glucosamine-6-phosphate isomerase, putative K02564; Psort location: Cytoplasmic, score: 8.87. (236 aa)
EEF65832.1Amidohydrolase; KEGG: sso:SSO1952 4.9e-59 cpsA-2; thermostable carboxypeptidase; Psort location: Cytoplasmic, score: 8.87. (427 aa)
EEF65813.1Hypothetical protein; Psort location: Cytoplasmic, score: 8.87. (379 aa)
EEF65814.1MBOAT family protein; KEGG: pen:PSEEN4543 1.5e-89 algI; alginate O-acetylation protein AlgI K00680; Psort location: CytoplasmicMembrane, score: 9.99; Belongs to the membrane-bound acyltransferase family. (465 aa)
EEF65740.1Hypothetical protein; Psort location: Cytoplasmic, score: 8.87. (165 aa)
EEF65745.1KEGG: cpf:CPF_1229 2.9e-38 histidinol phosphate phosphatase family protein K04486; Psort location: Cytoplasmic, score: 8.87; Belongs to the PHP hydrolase family. HisK subfamily. (266 aa)
EEF65703.1Phosphotransferase enzyme family; Psort location: Cytoplasmic, score: 8.87. (305 aa)
EEF65600.1EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase); KEGG: cpf:CPF_0689 2.1e-51 aroA; 3-phosphoshikimate 1-carboxyvinyltransferase K00800; Psort location: Cytoplasmic, score: 8.87. (293 aa)
Your Current Organism:
Holdemania filiformis
NCBI taxonomy Id: 545696
Other names: H. filiformis DSM 12042, Holdemania filiformis DSM 12042, Holdemania filiformis str. DSM 12042, Holdemania filiformis strain DSM 12042
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