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fruA_1 fruA_1 lacC lacC fruB fruB glk glk ptsH ptsH ptsI_2 ptsI_2 crr_1 crr_1 talA talA tktB_1 tktB_1 eno_2 eno_2 ptsI_1 ptsI_1 AOE38939.1 AOE38939.1 lutR_2 lutR_2 licB licB gmuD_2 gmuD_2 gmuC gmuC chbA chbA ybbH_2 ybbH_2 bglA_1 bglA_1 rpiA rpiA fbaA_1 fbaA_1 pgk pgk epd epd tktA tktA deoB deoB deoA deoA deoC deoC licR_2 licR_2 fbp fbp xpkA xpkA glpX glpX tpiA tpiA pfkA_1 pfkA_1 rbsK_2 rbsK_2 glmU_1 glmU_1 glmS glmS mtlD_2 mtlD_2 mtlA mtlA pgi pgi murQ murQ murP_2 murP_2 gcd_5 gcd_5 AOE39878.1 AOE39878.1 AOE39879.1 AOE39879.1 glkA glkA AOE39882.1 AOE39882.1 ptsO ptsO ptsN ptsN glmM_2 glmM_2 AOE40047.1 AOE40047.1 fba fba fruA_2 fruA_2 manP manP rbsK_5 rbsK_5 cobC_1 cobC_1 talB talB mak mak nagD nagD mlc_3 mlc_3 nagA nagA nagB nagB ptsG_6 ptsG_6 pgm_1 pgm_1 gpmA gpmA chb_1 chb_1 ptsG_5 ptsG_5 tktB_2 tktB_2 dxs_1 dxs_1 prs_1 prs_1 ptsG_2 ptsG_2 manA_2 manA_2 fbaA_2 fbaA_2 gcd_3 gcd_3 ptsG_1 ptsG_1 gapA gapA yeaD yeaD manX manX manY manY manZ manZ cutC cutC
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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fruA_1PTS fructose transporter subunit IIBC; Derived by automated computational analysis using gene prediction method: Protein Homology. (565 aa)
lacC1-phosphofructokinase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the carbohydrate kinase PfkB family. (312 aa)
fruBBifunctional PTS fructose transporter subunit IIA/HPr protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (376 aa)
glkGlucokinase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the bacterial glucokinase family. (321 aa)
ptsHPTS sugar transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. (85 aa)
ptsI_2Phosphoenolpyruvate--protein phosphotransferase; General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr). (575 aa)
crr_1PTS glucose transporter subunit IIA; Derived by automated computational analysis using gene prediction method: Protein Homology. (166 aa)
talATransaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway. (316 aa)
tktB_1Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate. (666 aa)
eno_2Phosphopyruvate hydratase; Derived by automated computational analysis using gene prediction method: Protein Homology. (431 aa)
ptsI_1Phosphoenolpyruvate--protein phosphotransferase PtsP; Member of a second PTS chain involved in nitrogen metabolism; PtsP phosphorylates NPr; Derived by automated computational analysis using gene prediction method: Protein Homology. (748 aa)
AOE38939.1GNAT family N-acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (150 aa)
lutR_2Transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (257 aa)
licBPTS sugar transporter subunit IIB; Derived by automated computational analysis using gene prediction method: Protein Homology. (105 aa)
gmuD_26-phospho-beta-glucosidase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the glycosyl hydrolase 1 family. (475 aa)
gmuCPTS lactose transporter subunit IIC; The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane. (449 aa)
chbAMolecular chaperone TorD; Derived by automated computational analysis using gene prediction method: Protein Homology. (102 aa)
ybbH_2Transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (239 aa)
bglA_16-phospho-beta-glucosidase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the glycosyl hydrolase 1 family. (479 aa)
rpiARibose 5-phosphate isomerase A; Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate. (219 aa)
fbaA_1Class II fructose-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family. (359 aa)
pgkPhosphoglycerate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the phosphoglycerate kinase family. (387 aa)
epdErythrose-4-phosphate dehydrogenase; Catalyzes the NAD-dependent conversion of D-erythrose 4- phosphate to 4-phosphoerythronate. (339 aa)
tktATransketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate. (664 aa)
deoBPhosphopentomutase; Phosphotransfer between the C1 and C5 carbon atoms of pentose; Belongs to the phosphopentomutase family. (407 aa)
deoAThymidine phosphorylase; The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis. Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family. (442 aa)
deoCDeoxyribose-phosphate aldolase; Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5- phosphate; Belongs to the DeoC/FbaB aldolase family. DeoC type 2 subfamily. (259 aa)
licR_2Transcription antiterminator BglG; Derived by automated computational analysis using gene prediction method: Protein Homology. (640 aa)
fbpFructose-bisphosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the FBPase class 1 family. (335 aa)
xpkAPhosphoketolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (794 aa)
glpXFructose-bisphosphatase, class II; Derived by automated computational analysis using gene prediction method: Protein Homology. (336 aa)
tpiATriose-phosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (255 aa)
pfkA_16-phosphofructokinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (320 aa)
rbsK_2Ribokinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (309 aa)
glmU_1UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. (456 aa)
glmSGlutamine--fructose-6-phosphate aminotransferase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. (609 aa)
mtlD_2Mannitol-1-phosphate 5-dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the mannitol dehydrogenase family. (382 aa)
mtlAPTS mannitol transporter subunit IICBA; Derived by automated computational analysis using gene prediction method: Protein Homology. (644 aa)
pgiGlucose-6-phosphate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the GPI family. (548 aa)
murQN-acetylmuramic acid 6-phosphate etherase; Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D- lactate. Together with AnmK, is also required for the utilization of anhydro-N-acetylmuramic acid (anhMurNAc) either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the GCKR-like family. MurNAc-6-P etherase subfamily. (303 aa)
murP_2PTS N-acetylmuramic acid transporter subunits IIBC; Derived by automated computational analysis using gene prediction method: Protein Homology. (484 aa)
gcd_5Quinoprotein glucose dehydrogenase; catalyzes the formation of D-glucono-1,5-lactone from D-glucose and ubiquinone; Derived by automated computational analysis using gene prediction method: Protein Homology. (796 aa)
AOE39878.1Oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (385 aa)
AOE39879.1N-acetylglucosamine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (294 aa)
glkAROK family protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (372 aa)
AOE39882.1GNAT family N-acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (199 aa)
ptsOPhosphohistidinoprotein-hexose phosphotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (90 aa)
ptsNPTS IIA-like nitrogen-regulatory protein PtsN; Derived by automated computational analysis using gene prediction method: Protein Homology. (159 aa)
glmM_2Phosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family. (444 aa)
AOE40047.1beta-N-acetylhexosaminidase; Derived by automated computational analysis using gene prediction method: Protein Homology. (790 aa)
fbaHypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (286 aa)
fruA_2PTS fructose transporter subunit IIBC; Derived by automated computational analysis using gene prediction method: Protein Homology. (474 aa)
manPDNA-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (157 aa)
rbsK_5Ribokinase; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway. (305 aa)
cobC_1Phosphoglycerate mutase; Catalyzes reactions involving the transfer of phospho groups between the three carbon atoms of phosphoglycerate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the phosphoglycerate mutase family. GpmB subfamily. (215 aa)
talBTransaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway. (317 aa)
makFructokinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (303 aa)
nagDUMP phosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology. (250 aa)
mlc_3Transcriptional regulator; Regulates the synthesis of glucosamine and N-acetylglucosamine by acting as a repressor of the nagEBACD operon and both a repressor and activator of the glmSU operon; Derived by automated computational analysis using gene prediction method: Protein Homology. (406 aa)
nagAN-acetylglucosamine-6-phosphate deacetylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (382 aa)
nagBGlucosamine-6-phosphate deaminase; Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion. (266 aa)
ptsG_6PTS N-acetyl glucosamine transporter subunit IIABC; Phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel; Derived by automated computational analysis using gene prediction method: Protein Homology. (675 aa)
pgm_1Phosphoglucomutase, alpha-D-glucose phosphate-specific; Catalyzes the interconversion of alpha-D-glucose 1-phosphate to alpha-D-glucose 6-phosphate; Derived by automated computational analysis using gene prediction method: Protein Homology. (546 aa)
gpmAPhosphoglyceromutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate; Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily. (250 aa)
chb_1beta-N-acetylhexosaminidase; Derived by automated computational analysis using gene prediction method: Protein Homology. (883 aa)
ptsG_5PTS glucose transporter subunit IIBC; Derived by automated computational analysis using gene prediction method: Protein Homology. (478 aa)
tktB_2Transketolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (276 aa)
dxs_1Transketolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (314 aa)
prs_1Ribose-phosphate pyrophosphokinase; Catalyzes the formation of 5-phospho-alpha-D-ribose 1-phosphate from D-ribose 5-phosphate and ATP; Derived by automated computational analysis using gene prediction method: Protein Homology. (312 aa)
ptsG_2PTS sugar transporter subunit IIBC; Phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS); catalyzes the phosphorylation of maltose and glucose concomitant with their translocation across the cell membrane; component IIB catalyzes the phosphorylation of the sugar molecule; IIC forms the translocation channel and contains the substrate specific binding site; Derived by automated computational analysis using gene prediction method: Protein Homology. (529 aa)
manA_2Mannose-6-phosphate isomerase; Catalyzes the formation of of fructose 6-phosphate from mannose 6-phosphate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the mannose-6-phosphate isomerase type 1 family. (391 aa)
fbaA_2Iron ABC transporter substrate-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (280 aa)
gcd_3Quinoprotein; Derived by automated computational analysis using gene prediction method: Protein Homology. (785 aa)
ptsG_1PTS maltose transporter subunit IICB; Derived by automated computational analysis using gene prediction method: Protein Homology. (528 aa)
gapAType I glyceraldehyde-3-phosphate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (332 aa)
yeaDD-hexose-6-phosphate mutarotase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the glucose-6-phosphate 1-epimerase family. (299 aa)
manXPTS mannose transporter subunit IIAB; Derived by automated computational analysis using gene prediction method: Protein Homology. (320 aa)
manYPTS mannose/fructose/sorbose transporter subunit IIC; Catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; the IIC domain forms the PTS system translocation channel and contains the specific substrate-binding site; Derived by automated computational analysis using gene prediction method: Protein Homology. (266 aa)
manZPTS mannose transporter subunit IID; Hosphoenolpyruvate-dependent sugar phosphotransferase system catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IID with IIC forms the translocation channel; Derived by automated computational analysis using gene prediction method: Protein Homology. (281 aa)
cutCCopper homeostasis protein CutC; Participates in the control of copper homeostasis. Belongs to the CutC family. (250 aa)
Your Current Organism:
Pantoea agglomerans
NCBI taxonomy Id: 549
Other names: ATCC 27155, Bacillus milletiae, Bacterium herbicola, CCUG 539, CFBP 3845, CIP 57.51, DSM 3493, Enterobacter agglomerans, Erwinia herbicola, Erwinia milletiae, ICMP 12534, ICPB 3435, NBRC 102470, NCTC 9381, P. agglomerans, Pantoea herbicola, Pantoea sp. SL1_M5, Pseudomonas herbicola, bacterium G33-1
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