STRINGSTRING
ACT04908.1 ACT04908.1 ACT04981.1 ACT04981.1 ACT04984.1 ACT04984.1 sthA sthA ACT05031.1 ACT05031.1 ACT05093.1 ACT05093.1 ACT05272.1 ACT05272.1 ACT05463.1 ACT05463.1 ACT05478.1 ACT05478.1 ACT05518.1 ACT05518.1 ACT05534.1 ACT05534.1 dusA dusA ACT05665.1 ACT05665.1 cysJ cysJ ACT05769.1 ACT05769.1 hmp hmp mnmC mnmC ACT06303.1 ACT06303.1 ACT06457.1 ACT06457.1 ACT06544.1 ACT06544.1 ACT06833.1 ACT06833.1 ACT06943.1 ACT06943.1 ACT07213.1 ACT07213.1 dusC dusC ACT07690.1 ACT07690.1 ACT07738.1 ACT07738.1 ACT07769.1 ACT07769.1 ACT07773.1 ACT07773.1 ACT08374.1 ACT08374.1 ACT08375.1 ACT08375.1 ACT08382.1 ACT08382.1 ACT08404.1 ACT08404.1 ACT08405.1 ACT08405.1 dusB dusB murB murB mnmG mnmG
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
Your Input:
ACT04908.1TIGRFAM: glutathione-disulfide reductase; PFAM: pyridine nucleotide-disulphide oxidoreductase dimerisation region; FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: eca:ECA0062 glutathione reductase. (450 aa)
ACT04981.1PFAM: acyl-CoA dehydrogenase domain protein; KEGG: plu:plu0762 hypothetical protein. (378 aa)
ACT04984.1PFAM: acyl-CoA dehydrogenase domain protein; KEGG: plu:plu0762 hypothetical protein. (377 aa)
sthAPyridine nucleotide-disulphide oxidoreductase dimerisation region; Conversion of NADPH, generated by peripheral catabolic pathways, to NADH, which can enter the respiratory chain for energy generation; Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. (468 aa)
ACT05031.1TIGRFAM: acetolactate synthase, large subunit, biosynthetic type; PFAM: thiamine pyrophosphate protein TPP binding domain protein; thiamine pyrophosphate protein domain protein TPP-binding; thiamine pyrophosphate protein central region; KEGG: eca:ECA4229 acetolactate synthase 2 catalytic subunit. (548 aa)
ACT05093.1TIGRFAM: glycerol-3-phosphate dehydrogenase, anaerobic, A subunit; PFAM: FAD dependent oxidoreductase; BFD domain protein [2Fe-2S]-binding domain protein; KEGG: eca:ECA4165 sn-glycerol-3-phosphate dehydrogenase subunit A; Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family. (547 aa)
ACT05272.1TIGRFAM: fumarate reductase, flavoprotein subunit; succinate dehydrogenase or fumarate reductase, flavoprotein subunit; PFAM: fumarate reductase/succinate dehydrogenase flavoprotein domain protein; KEGG: eca:ECA3969 fumarate reductase flavoprotein subunit. (598 aa)
ACT05463.1TIGRFAM: acetolactate synthase, large subunit, biosynthetic type; PFAM: thiamine pyrophosphate protein TPP binding domain protein; thiamine pyrophosphate protein central region; thiamine pyrophosphate protein domain protein TPP-binding; KEGG: eca:ECA3848 acetolactate synthase catalytic subunit. (554 aa)
ACT05478.1TIGRFAM: acetolactate synthase, large subunit, biosynthetic type; PFAM: thiamine pyrophosphate protein TPP binding domain protein; thiamine pyrophosphate protein domain protein TPP-binding; thiamine pyrophosphate protein central region; KEGG: eca:ECA3829 acetolactate synthase 3 catalytic subunit. (573 aa)
ACT05518.1TIGRFAM: dihydrolipoamide dehydrogenase; PFAM: pyridine nucleotide-disulphide oxidoreductase dimerisation region; FAD-dependent pyridine nucleotide-disulphide oxidoreductase; glucose-inhibited division protein A; KEGG: esa:ESA_03220 dihydrolipoamide dehydrogenase. (474 aa)
ACT05534.1PFAM: 4-hydroxyphenylacetate 3-hydroxylase; KEGG: bha:BH3836 4-hydroxyphenylacetate-3-hydroxylase. (505 aa)
dusATIM-barrel protein, yjbN family; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U20 and U20a in tRNAs; Belongs to the Dus family. DusA subfamily. (344 aa)
ACT05665.1PFAM: protein of unknown function DUF21; CBS domain containing protein; transporter-associated region; KEGG: eca:ECA3598 hypothetical protein. (438 aa)
cysJSulfite reductase (NADPH) flavoprotein, alpha chain; Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH -> FAD -> FMN to the hemoprotein component. Belongs to the NADPH-dependent sulphite reductase flavoprotein subunit CysJ family. In the N-terminal section; belongs to the flavodoxin family. (607 aa)
ACT05769.1PFAM: Protein of unknown function DUF1974; acyl-CoA dehydrogenase domain protein; KEGG: eca:ECA3474 acyl-CoA dehydrogenase. (814 aa)
hmpGlobin; Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress; Belongs to the globin family. Two-domain flavohemoproteins subfamily. (395 aa)
mnmCtRNA U-34 5-methylaminomethyl-2-thiouridine biosynthesis protein MnmC; Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34; In the C-terminal section; belongs to the DAO family. (672 aa)
ACT06303.1TIGRFAM: nitrite reductase [NAD(P)H], large subunit; nitrite reductase [NAD(P)H], small subunit; PFAM: nitrite and sulphite reductase 4Fe-4S region; FAD-dependent pyridine nucleotide-disulphide oxidoreductase; BFD domain protein [2Fe-2S]-binding domain protein; nitrite/sulfite reductase hemoprotein beta-component ferrodoxin domain protein; KEGG: eca:ECA2991 nitrite reductase [NAD(P)H] large subunit. (1386 aa)
ACT06457.1KEGG: eca:ECA1775 putative iron-regulated membrane protein. (495 aa)
ACT06544.1PFAM: FAD linked oxidase domain protein; KEGG: eca:ECA1856 putative FAD-binding oxidase. (1019 aa)
ACT06833.1PFAM: Integral membrane protein TerC; CBS domain containing protein; transporter-associated region; KEGG: eca:ECA2384 hypothetical protein. (517 aa)
ACT06943.1KEGG: ret:RHE_PF00443 putative dehydrogenase large subunit protein. (612 aa)
ACT07213.1PFAM: ferredoxin; oxidoreductase FAD/NAD(P)-binding domain protein; Oxidoreductase FAD-binding domain protein; KEGG: eca:ECA2663 HCP oxidoreductase, NADH-dependent. (335 aa)
dusCDihydrouridine synthase DuS; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U16 in tRNAs. Belongs to the Dus family. DusC subfamily. (311 aa)
ACT07690.1PFAM: Integral membrane protein TerC; CBS domain containing protein; transporter-associated region; KEGG: spe:Spro_1580 integral membrane protein TerC. (529 aa)
ACT07738.1TIGRFAM: succinate dehydrogenase or fumarate reductase, flavoprotein subunit; succinate dehydrogenase, flavoprotein subunit; PFAM: fumarate reductase/succinate dehydrogenase flavoprotein domain protein; KEGG: esa:ESA_02624 succinate dehydrogenase flavoprotein subunit; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily. (588 aa)
ACT07769.1TIGRFAM: Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family; PFAM: monooxygenase FAD-binding; FAD dependent oxidoreductase; KEGG: eca:ECA1320 2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase. (388 aa)
ACT07773.1PFAM: CBS domain containing protein; transporter-associated region; SMART: CBS domain containing protein; KEGG: eca:ECA1316 magnesium and cobalt efflux protein corc. (289 aa)
ACT08374.1PFAM: monooxygenase FAD-binding; KEGG: kpn:KPN_01663 putative flavoprotein monooxygenase. (384 aa)
ACT08375.1PFAM: ferredoxin; oxidoreductase FAD/NAD(P)-binding domain protein; Oxidoreductase FAD-binding domain protein; KEGG: eta:ETA_33390 vanillate O-demethylase oxidoreductase. (322 aa)
ACT08382.1TIGRFAM: alkyl hydroperoxide reductase, F subunit; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: eca:ECA3941 alkyl hydroperoxide reductase subunit F. (520 aa)
ACT08404.1TIGRFAM: 2-polyprenyl-6-methoxyphenol 4-hydroxylase; Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family; PFAM: monooxygenase FAD-binding; KEGG: eca:ECA0458 2-octaprenyl-6-methoxyphenyl hydroxylase. (392 aa)
ACT08405.1TIGRFAM: Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family; PFAM: monooxygenase FAD-binding; KEGG: eca:ECA0457 hypothetical protein. (403 aa)
dusBTIM-barrel protein, nifR3 family; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the Dus family. DusB subfamily. (321 aa)
murBUDP-N-acetylenolpyruvoylglucosamine reductase; Cell wall formation. (345 aa)
mnmGGlucose inhibited division protein A; NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34; Belongs to the MnmG family. (629 aa)
Your Current Organism:
Dickeya chrysanthemi
NCBI taxonomy Id: 561229
Other names: D. chrysanthemi Ech1591, Dickeya chrysanthemi Ech1591, Dickeya dadantii Ech1591, Dickeya zeae Ech1591
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