(35 nodes) Actin cortical patch network (Fusarium venenatum)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	A0A2L2TL05	Uncharacterized protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1221 aa)
	A0A2L2TG86	Uncharacterized protein. (618 aa)
	A0A2L2TFC5	Uncharacterized protein. (649 aa)
	A0A2L2TF17	SH3 domain-containing protein. (1255 aa)
	A0A2L2TCX3	Uncharacterized protein. (808 aa)
	A0A2L2TC17	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family. (1683 aa)
	A0A2L2TAH2	Uncharacterized protein. (717 aa)
	A0A2L2TAE4	WD_REPEATS_REGION domain-containing protein. (610 aa)
	A0A2L2T9L3	Uncharacterized protein. (265 aa)
	A0A2L2T856	ADF-H domain-containing protein. (142 aa)
	A0A2L2T7V8	Uncharacterized protein. (434 aa)
	A0A2L2T6R3	Uncharacterized protein. (437 aa)
	A0A2L2T670	Uncharacterized protein. (1126 aa)
	A0A2L2T5D3	SH3 domain-containing protein. (401 aa)
	A0A2L2T584	BAR domain-containing protein. (261 aa)
	A0A2L2T3U7	Actin-related protein 2/3 complex subunit 3; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (192 aa)
	A0A2L2T331	Uncharacterized protein. (832 aa)
	A0A2L2T0F9	Coronin; Belongs to the WD repeat coronin family. (594 aa)
	A0A2L2SWZ3	Uncharacterized protein. (1054 aa)
	A0A2L2SW39	Uncharacterized protein. (610 aa)
	A0A2L2SUL0	Actin-related protein 2/3 complex subunit 4; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Seems to contact the mother actin filament; Belongs to the ARPC4 family. (169 aa)
	A0A2L2SU92	Calponin-homology (CH) domain-containing protein. (674 aa)
	A0A2L2SU18	Uncharacterized protein. (1465 aa)
	A0A2L2SSH4	Uncharacterized protein. (397 aa)
	A0A2L2SNS4	Uncharacterized protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (695 aa)
	A0A2L2TNC9	E3 ubiquitin-protein ligase. (810 aa)
	A0A2L2TQP9	Actin-related protein 2; ATP-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility. Seems to contact the pointed end of the daughter actin filament. (390 aa)
	A0A2L2TS67	Uncharacterized protein. (1247 aa)
	A0A2L2TSU8	IPPc domain-containing protein. (1226 aa)
	A0A2L2TV95	Actin-related protein 2/3 complex subunit; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks; Belongs to the WD repeat ARPC1 family. (363 aa)
	A0A2L2TW78	WH2 domain-containing protein. (418 aa)
	A0A2L2TY33	Adenylyl cyclase-associated protein; Belongs to the CAP family. (565 aa)
	A0A2L2U0J8	Uncharacterized protein. (737 aa)
	A0A2L2U2P7	DUF2013 domain-containing protein. (499 aa)
	A0A2L2U300	Uncharacterized protein; Belongs to the actin family. (439 aa)

Your Current Organism:

Fusarium venenatum

NCBI taxonomy Id: 56646
Other names: CBS 458.93, F. venenatum, Fusarium venetum

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Browse interactions in tabular form:

node1	node2	node1 annotation	node2 annotation	score
A0A2L2SNS4	A0A2L2SU18	Uncharacterized protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	Uncharacterized protein.	0.506
A0A2L2SNS4	A0A2L2SW39	Uncharacterized protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	Uncharacterized protein.	0.700
A0A2L2SNS4	A0A2L2SWZ3	Uncharacterized protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	Uncharacterized protein.	0.827
A0A2L2SNS4	A0A2L2T584	Uncharacterized protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	BAR domain-containing protein.	0.847
A0A2L2SNS4	A0A2L2T7V8	Uncharacterized protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	Uncharacterized protein.	0.702
A0A2L2SNS4	A0A2L2TC17	Uncharacterized protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family.	0.865
A0A2L2SNS4	A0A2L2TS67	Uncharacterized protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	Uncharacterized protein.	0.506
A0A2L2SNS4	A0A2L2TSU8	Uncharacterized protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	IPPc domain-containing protein.	0.471
A0A2L2SNS4	A0A2L2U0J8	Uncharacterized protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	Uncharacterized protein.	0.489
A0A2L2SSH4	A0A2L2SU18	Uncharacterized protein.	Uncharacterized protein.	0.858
A0A2L2SSH4	A0A2L2SW39	Uncharacterized protein.	Uncharacterized protein.	0.879
A0A2L2SSH4	A0A2L2SWZ3	Uncharacterized protein.	Uncharacterized protein.	0.763
A0A2L2SSH4	A0A2L2T331	Uncharacterized protein.	Uncharacterized protein.	0.506
A0A2L2SSH4	A0A2L2T584	Uncharacterized protein.	BAR domain-containing protein.	0.569
A0A2L2SSH4	A0A2L2T670	Uncharacterized protein.	Uncharacterized protein.	0.780
A0A2L2SSH4	A0A2L2T7V8	Uncharacterized protein.	Uncharacterized protein.	0.554
A0A2L2SSH4	A0A2L2TC17	Uncharacterized protein.	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family.	0.850
A0A2L2SSH4	A0A2L2TFC5	Uncharacterized protein.	Uncharacterized protein.	0.428
A0A2L2SSH4	A0A2L2TL05	Uncharacterized protein.	Uncharacterized protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.	0.414
A0A2L2SSH4	A0A2L2TNC9	Uncharacterized protein.	E3 ubiquitin-protein ligase.	0.440