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| | PAN3 | PAN2-PAN3 deadenylation complex subunit PAN3; Regulatory subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in mRNA turnover. PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein PAB1. PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex. Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent mRNA decaping and subsequent 5'-3' exo [...] (667 aa) |
| | PV07_12723 | EST1_DNA_bind domain-containing protein. (789 aa) |
| | PV07_12563 | 3'-5' exonuclease domain-containing protein. (321 aa) |
| | PV07_12556 | C3H1-type domain-containing protein. (2005 aa) |
| | PV07_12477 | Translation elongation factor Tu. (618 aa) |
| | PV07_11032 | Uncharacterized protein. (1045 aa) |
| | PV07_10330 | WD_REPEATS_REGION domain-containing protein. (558 aa) |
| | PV07_10450 | Uncharacterized protein. (525 aa) |
| | PV07_10492 | Tr-type G domain-containing protein. (696 aa) |
| | PV07_10728 | Uncharacterized protein. (853 aa) |
| | PV07_08915 | Uncharacterized protein. (1257 aa) |
| | PV07_09150 | Uncharacterized protein. (778 aa) |
| | PV07_09243 | Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (1301 aa) |
| | PV07_06758 | Uncharacterized protein. (495 aa) |
| | PV07_06807 | Uncharacterized protein. (864 aa) |
| | PV07_06904 | RRM domain-containing protein. (683 aa) |
| | PV07_06958 | PUM-HD domain-containing protein. (911 aa) |
| | PV07_06975 | Uncharacterized protein. (328 aa) |
| | PV07_07210 | RAI1 domain-containing protein. (392 aa) |
| | PV07_07414 | Uncharacterized protein. (1334 aa) |
| | PV07_07999 | ATP-dependent RNA helicase dhh1; Belongs to the DEAD box helicase family. (518 aa) |
| | PV07_05170 | PUM-HD domain-containing protein. (995 aa) |
| | PV07_05791 | Guanine nucleotide-binding protein subunit beta-like protein. (316 aa) |
| | PV07_02463 | Uncharacterized protein. (658 aa) |
| | PV07_02583 | RNA-dependent RNA polymerase. (1172 aa) |
| | PV07_02603 | Uncharacterized protein. (252 aa) |
| | PV07_03086 | Nudix hydrolase domain-containing protein. (379 aa) |
| | PV07_03621 | Stress-response A/B barrel domain-containing protein. (102 aa) |
| | PV07_00237 | Uncharacterized protein. (496 aa) |
| | PV07_00337 | Uncharacterized protein. (210 aa) |
| | PV07_01904 | 3'-5' exonuclease domain-containing protein. (379 aa) |
| | PV07_02302 | Stress-response A/B barrel domain-containing protein. (123 aa) |
| | PV07_12667 | Uncharacterized protein. (323 aa) |
| | PV07_12153 | Uncharacterized protein. (271 aa) |
| | PV07_11365 | Uncharacterized protein. (1207 aa) |
| | PV07_11503 | Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (324 aa) |
| | PV07_11980 | 5'-3' exoribonuclease; Possesses 5'->3' exoribonuclease activity. May promote termination of transcription by RNA polymerase II. (1031 aa) |
| | PV07_09679 | Stress-response A/B barrel domain-containing protein. (98 aa) |
| | PV07_09727 | RNase III domain-containing protein. (297 aa) |
| | PV07_09902 | Uncharacterized protein. (506 aa) |
| | PV07_10034 | RNA-dependent RNA polymerase. (1413 aa) |
| | PV07_10141 | Non-specific serine/threonine protein kinase. (872 aa) |
| | PV07_10678 | Deacetylase sirtuin-type domain-containing protein. (649 aa) |
| | PV07_08698 | Uncharacterized protein. (856 aa) |
| | PV07_08729 | Protein kinase domain-containing protein. (206 aa) |
| | PV07_09100 | DNA helicase; Belongs to the MCM family. (904 aa) |
| | PV07_09423 | Uncharacterized protein. (255 aa) |
| | MCM7 | DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] (814 aa) |
| | PV07_06436 | AAA_12 domain-containing protein. (499 aa) |
| | PV07_06933 | zf-C3H1 domain-containing protein. (1434 aa) |
| | PV07_07073 | TPR_REGION domain-containing protein. (820 aa) |
| | PV07_07115 | Uncharacterized protein. (1681 aa) |
| | PV07_08305 | HRDC domain-containing protein. (847 aa) |
| | PV07_04641 | Helicase ATP-binding domain-containing protein. (1079 aa) |
| | PV07_04922 | Uncharacterized protein. (592 aa) |
| | PV07_05393 | Uncharacterized protein. (1576 aa) |
| | PV07_05712 | Uncharacterized protein. (263 aa) |
| | PV07_05796 | NAD-dependent protein deacetylase; Belongs to the sirtuin family. Class I subfamily. (385 aa) |
| | PV07_02999 | KH_dom_type_1 domain-containing protein. (247 aa) |
| | PV07_04035 | ATP-dependent RNA helicase DBP2; Belongs to the DEAD box helicase family. (526 aa) |
| | PV07_00209 | CBFD_NFYB_HMF domain-containing protein. (196 aa) |
| | PV07_00497 | CULLIN_2 domain-containing protein; Belongs to the cullin family. (903 aa) |
| | PV07_00601 | Histone-lysine N-methyltransferase, H3 lysine-79 specific; Histone methyltransferase that specifically methylates histone H3 to form H3K79me. This methylation is required for telomere silencing and for the pachytene checkpoint during the meiotic cell cycle by allowing the recruitment of RAD9 to double strand breaks. Nucleosomes are preferred as substrate compared to free histones. (540 aa) |
| | PV07_00712 | Uncharacterized protein. (278 aa) |
| | PV07_00849 | RNase III domain-containing protein. (180 aa) |
| | PV07_01070 | Protein kinase domain-containing protein. (728 aa) |
| | PV07_01107 | Uncharacterized protein; Belongs to the helicase family. Dicer subfamily. (1567 aa) |
| | PV07_01439 | Uncharacterized protein. (504 aa) |
| | PV07_01682 | Sm domain-containing protein. (136 aa) |
| | PV07_02043 | Uncharacterized protein. (470 aa) |
| | PV07_12774 | Uncharacterized protein. (221 aa) |
| | PV07_12213 | Uncharacterized protein. (1194 aa) |
| | PV07_10849 | Uncharacterized protein. (446 aa) |
| | PV07_10952 | zf-GRF domain-containing protein. (332 aa) |
| | PV07_11024 | RRM domain-containing protein. (478 aa) |
| | PV07_11039 | Flavin_Reduct domain-containing protein. (336 aa) |
| | PV07_11123 | Hsp90-like protein. (702 aa) |
| | LSM1 | U6 snRNA-associated Sm-like protein LSm1; Component of the cytoplasmic LSM1-LSM7 complex which is involved in mRNA degradation. (201 aa) |
| | PV07_12222 | Uncharacterized protein; Belongs to the helicase family. Dicer subfamily. (1430 aa) |
| | PV07_10882 | C2H2-type domain-containing protein. (926 aa) |
| | PV07_11531 | C3H1-type domain-containing protein. (1772 aa) |
| | PV07_11556 | NTP_transf_9 domain-containing protein. (163 aa) |
| | PV07_11662 | Endo/exonuclease/phosphatase domain-containing protein. (746 aa) |
| | PV07_11538 | PHD-type domain-containing protein. (608 aa) |
| | PV07_11543 | Uncharacterized protein. (2120 aa) |
| | PV07_11768 | S1 domain-containing protein. (169 aa) |
| | PV07_10137 | Chromo domain-containing protein. (270 aa) |
| | PV07_10428 | Uncharacterized protein. (246 aa) |
| | PV07_10069 | Uncharacterized protein. (1147 aa) |
| | PV07_08774 | Uncharacterized protein. (1397 aa) |
| | PV07_10784 | Uncharacterized protein; Belongs to the DEAD box helicase family. (640 aa) |
| | PV07_08398 | Nuclear cap-binding protein subunit 2. (172 aa) |
| | PV07_09152 | Stc1 domain-containing protein. (261 aa) |
| | PV07_08656 | Hist_deacetyl domain-containing protein. (324 aa) |
| | PV07_09227 | FACT complex subunit POB3; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment of [...] (569 aa) |
| | PV07_07054 | RING-box protein 1A. (124 aa) |
| | PV07_07134 | Non-specific serine/threonine protein kinase. (889 aa) |
| | PV07_07211 | tRNA dimethylallyltransferase. (501 aa) |
| | PV07_06907 | Uncharacterized protein. (460 aa) |
| | PV07_07643 | Uncharacterized protein. (449 aa) |
| | PV07_07718 | NTP_transf_9 domain-containing protein. (261 aa) |
| | PV07_07204 | RNase_PH domain-containing protein. (362 aa) |
| | PV07_07942 | Uncharacterized protein. (632 aa) |
| | PV07_08207 | Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (462 aa) |
| | PV07_07715 | S1 motif domain-containing protein. (349 aa) |
| | PV07_07759 | Protein DOM34 homolog; May function in recognizing stalled ribosomes and triggering endonucleolytic cleavage of the mRNA, a mechanism to release non- functional ribosomes and degrade damaged mRNAs. (417 aa) |
| | PV07_12794 | 3'-5' exonuclease domain-containing protein. (313 aa) |
| | PV07_05326 | Uncharacterized protein. (604 aa) |
| | PV07_12155 | SAM domain-containing protein. (616 aa) |
| | PV07_04764 | Uncharacterized protein. (1481 aa) |
| | PV07_04874 | PUM-HD domain-containing protein. (813 aa) |
| | LSM4 | U6 snRNA-associated Sm-like protein LSm4; Binds specifically to the 3'-terminal U-tract of U6 snRNA. (141 aa) |
| | PV07_05928 | Uncharacterized protein. (425 aa) |
| | PV07_11066 | CCHC-type domain-containing protein. (579 aa) |
| | PV07_05505 | 5'-3' exoribonuclease 1; Multifunctional protein that exhibits several independent functions at different levels of the cellular processes. 5'-3' exonuclease component of the nonsense-mediated mRNA decay (NMD) which is a highly conserved mRNA degradation pathway, an RNA surveillance system whose role is to identify and rid cells of mRNA with premature termination codons and thus prevents accumulation of potentially harmful truncated proteins. (1415 aa) |
| | PV07_06379 | ATP-dependent RNA helicase ded1; Belongs to the DEAD box helicase family. (699 aa) |
| | PV07_05641 | Uncharacterized protein. (528 aa) |
| | PV07_11537 | Uncharacterized protein. (1859 aa) |
| | PAN2 | PAN2-PAN3 deadenylation complex catalytic subunit PAN2; Catalytic subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in mRNA turnover. PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein PAB1. PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex. Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent mRNA decaping and subsequent [...] (1189 aa) |
| | PV07_11643 | Fungal_trans domain-containing protein. (379 aa) |
| | PV07_05851 | DNA helicase; Belongs to the MCM family. (725 aa) |
| | PV07_02823 | Uncharacterized protein. (268 aa) |
| | PV07_05942 | Uncharacterized protein; Belongs to the eukaryotic initiation factor 4E family. (226 aa) |
| | PV07_03270 | 60S ribosomal protein L16; Belongs to the universal ribosomal protein uL13 family. (201 aa) |
| | PV07_06389 | Uncharacterized protein; Belongs to the RNR ribonuclease family. (1006 aa) |
| | PV07_02421 | RNase_PH domain-containing protein. (258 aa) |
| | PV07_03447 | WD_REPEATS_REGION domain-containing protein. (321 aa) |
| | PV07_02482 | WD_REPEATS_REGION domain-containing protein. (476 aa) |
| | PV07_02496 | Hist_deacetyl domain-containing protein. (364 aa) |
| | PV07_02538 | Poly(A) polymerase; Polymerase that creates the 3'-poly(A) tail of mRNA's. (626 aa) |
| | PV07_10161 | Histone acetyltransferase type B catalytic subunit; Catalytic component of the histone acetylase B (HAT-B) complex. Has intrinsic substrate specificity that modifies lysine in recognition sequence GXGKXG. Involved in DNA double-strand break repair; Belongs to the HAT1 family. (491 aa) |
| | PV07_03862 | Uncharacterized protein. (548 aa) |
| | PV07_04173 | RNA-dependent RNA polymerase. (1369 aa) |
| | PV07_10798 | Uncharacterized protein. (263 aa) |
| | PV07_04396 | Uncharacterized protein. (545 aa) |
| | PV07_08402 | W2 domain-containing protein. (425 aa) |
| | PV07_08475 | PAP-associated domain-containing protein. (1339 aa) |
| | PV07_08726 | CNOT1_CAF1_bind domain-containing protein. (127 aa) |
| | PV07_08815 | Uncharacterized protein; Belongs to the helicase family. Dicer subfamily. (1385 aa) |
| | PV07_03599 | Uncharacterized protein. (409 aa) |
| | PV07_03695 | Deacetylase sirtuin-type domain-containing protein. (608 aa) |
| | PV07_00296 | PAT1 domain-containing protein. (821 aa) |
| | PV07_09163 | RNase_PH domain-containing protein. (359 aa) |
| | PV07_04095 | Ribosomal protein L13. (170 aa) |
| | PV07_04267 | Uncharacterized protein. (703 aa) |
| | PV07_01054 | Uncharacterized protein. (347 aa) |
| | PV07_06911 | Uncharacterized protein. (880 aa) |
| | PV07_07140 | EST1_DNA_bind domain-containing protein. (803 aa) |
| | PV07_00569 | Nudix hydrolase domain-containing protein. (893 aa) |
| | PV07_07327 | Uncharacterized protein. (1104 aa) |
| | PV07_07545 | Uncharacterized protein. (1555 aa) |
| | PV07_01087 | Uncharacterized protein. (473 aa) |
| | PV07_01131 | Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. (846 aa) |
| | PV07_07816 | Uncharacterized protein. (1401 aa) |
| | PV07_01198 | Uncharacterized protein. (557 aa) |
| | PV07_02235 | Stress-response A/B barrel domain-containing protein. (100 aa) |
| | PV07_05465 | Uncharacterized protein. (625 aa) |
| | PV07_05694 | Uncharacterized protein. (291 aa) |
| | PV07_03098 | RNB domain-containing protein. (1366 aa) |
| | PV07_03112 | Uncharacterized protein. (483 aa) |
| | PV07_03213 | RXT2_N domain-containing protein. (507 aa) |
| | PV07_03396 | Rtt106 domain-containing protein. (524 aa) |
| | PV07_03453 | PUM-HD domain-containing protein. (698 aa) |
| | PV07_03565 | Deacetylase sirtuin-type domain-containing protein. (540 aa) |
| | PV07_03586 | Uncharacterized protein. (302 aa) |
| | PV07_00499 | Uncharacterized protein. (1158 aa) |
| | PV07_00508 | TMF_TATA_bd domain-containing protein. (832 aa) |
| | PV07_00719 | Uncharacterized protein. (254 aa) |
| | PV07_00748 | Uncharacterized protein. (703 aa) |
| | PV07_01202 | CPSF_A domain-containing protein. (1197 aa) |
| | PV07_02087 | Uncharacterized protein. (245 aa) |
