(14 nodes) mRNA 3-end processing network (Trichomonas vaginalis)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	TVAG_437970	RNA-metabolising metallo-beta-lactamase family protein. (679 aa)
	TVAG_077030	CPSF A subunit region family protein. (1297 aa)
	TVAG_475950	Cleavage and polyadenylation specificity factor subunit 5; Component of the cleavage factor Im (CFIm) complex that functions as an activator of the pre-mRNA 3'-end cleavage and polyadenylation processing required for the maturation of pre-mRNA into functional mRNAs. CFIm contributes to the recruitment of multiprotein complexes on specific sequences on the pre-mRNA 3'-end, so called cleavage and polyadenylation signals (pA signals). Most pre-mRNAs contain multiple pA signals, resulting in alternative cleavage and polyadenylation (APA) producing mRNAs with variable 3'-end formation. The [...] (191 aa)
	TVAG_391250	Poly polymerase central domain containing protein. (467 aa)
	TVAG_162880	Uncharacterized protein. (395 aa)
	TVAG_494090	Symplekin_C domain-containing protein. (804 aa)
	TVAG_388620	Poly(A) polymerase; Polymerase that creates the 3'-poly(A) tail of mRNA's. (494 aa)
	TVAG_127020	Poly(A) polymerase; Polymerase that creates the 3'-poly(A) tail of mRNA's. (508 aa)
	TVAG_363680	Cleavage and polyadenylation specificity factor subunit 2. (700 aa)
	TVAG_343030	Suf domain-containing protein. (614 aa)
	TVAG_324910	RRM domain-containing protein. (124 aa)
	TVAG_317830	Uncharacterized protein. (398 aa)
	TVAG_123470	CDC73_C domain-containing protein. (385 aa)
	TVAG_229140	SSU72 protein-related protein. (204 aa)

Your Current Organism:

Trichomonas vaginalis

NCBI taxonomy Id: 5722
Other names: T. vaginalis, Tritrichomonas vaginalis

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
TVAG_077030	TVAG_127020	A2D9V0	A2E7X0	CPSF A subunit region family protein.	Poly(A) polymerase; Polymerase that creates the 3'-poly(A) tail of mRNA's.	0.972
TVAG_077030	TVAG_162880	A2D9V0	A2DFW6	CPSF A subunit region family protein.	Uncharacterized protein.	0.941
TVAG_077030	TVAG_229140	A2D9V0	A2FVC5	CPSF A subunit region family protein.	SSU72 protein-related protein.	0.998
TVAG_077030	TVAG_317830	A2D9V0	A2F3N0	CPSF A subunit region family protein.	Uncharacterized protein.	0.941
TVAG_077030	TVAG_324910	A2D9V0	A2F126	CPSF A subunit region family protein.	RRM domain-containing protein.	0.999
TVAG_077030	TVAG_343030	A2D9V0	A2EJR5	CPSF A subunit region family protein.	Suf domain-containing protein.	0.999
TVAG_077030	TVAG_363680	A2D9V0	A2EDT7	CPSF A subunit region family protein.	Cleavage and polyadenylation specificity factor subunit 2.	0.999
TVAG_077030	TVAG_388620	A2D9V0	A2DYJ5	CPSF A subunit region family protein.	Poly(A) polymerase; Polymerase that creates the 3'-poly(A) tail of mRNA's.	0.972
TVAG_077030	TVAG_391250	A2D9V0	A2DFN8	CPSF A subunit region family protein.	Poly polymerase central domain containing protein.	0.972
TVAG_077030	TVAG_437970	A2D9V0	A2FCF8	CPSF A subunit region family protein.	RNA-metabolising metallo-beta-lactamase family protein.	0.999
TVAG_077030	TVAG_475950	A2D9V0	A2DA19	CPSF A subunit region family protein.	Cleavage and polyadenylation specificity factor subunit 5; Component of the cleavage factor Im (CFIm) complex that functions as an activator of the pre-mRNA 3'-end cleavage and polyadenylation processing required for the maturation of pre-mRNA into functional mRNAs. CFIm contributes to the recruitment of multiprotein complexes on specific sequences on the pre-mRNA 3'-end, so called cleavage and polyadenylation signals (pA signals). Most pre-mRNAs contain multiple pA signals, resulting in alternative cleavage and polyadenylation (APA) producing mRNAs with variable 3'-end formation. The [...]	0.942
TVAG_077030	TVAG_494090	A2D9V0	A2DQ40	CPSF A subunit region family protein.	Symplekin_C domain-containing protein.	0.999
TVAG_123470	TVAG_127020	A2FCS3	A2E7X0	CDC73_C domain-containing protein.	Poly(A) polymerase; Polymerase that creates the 3'-poly(A) tail of mRNA's.	0.423
TVAG_123470	TVAG_229140	A2FCS3	A2FVC5	CDC73_C domain-containing protein.	SSU72 protein-related protein.	0.609
TVAG_123470	TVAG_324910	A2FCS3	A2F126	CDC73_C domain-containing protein.	RRM domain-containing protein.	0.510
TVAG_123470	TVAG_343030	A2FCS3	A2EJR5	CDC73_C domain-containing protein.	Suf domain-containing protein.	0.507
TVAG_123470	TVAG_363680	A2FCS3	A2EDT7	CDC73_C domain-containing protein.	Cleavage and polyadenylation specificity factor subunit 2.	0.548
TVAG_123470	TVAG_388620	A2FCS3	A2DYJ5	CDC73_C domain-containing protein.	Poly(A) polymerase; Polymerase that creates the 3'-poly(A) tail of mRNA's.	0.423
TVAG_123470	TVAG_391250	A2FCS3	A2DFN8	CDC73_C domain-containing protein.	Poly polymerase central domain containing protein.	0.423
TVAG_123470	TVAG_437970	A2FCS3	A2FCF8	CDC73_C domain-containing protein.	RNA-metabolising metallo-beta-lactamase family protein.	0.710