STRINGSTRING
gpmI gpmI EDC28_107213 EDC28_107213 rnfC rnfC EDC28_1036 EDC28_1036 accA accA prs prs EDC28_103248 EDC28_103248 EDC28_103265 EDC28_103265 EDC28_103266 EDC28_103266 tal tal pgi pgi EDC28_103396 EDC28_103396 EDC28_103397 EDC28_103397 EDC28_103406 EDC28_103406 EDC28_10639 EDC28_10639 EDC28_106155 EDC28_106155 EDC28_106158 EDC28_106158 tpiA tpiA maeA maeA EDC28_106262 EDC28_106262 EDC28_106273 EDC28_106273 EDC28_106274 EDC28_106274 EDC28_106304 EDC28_106304 fabV fabV EDC28_108180 EDC28_108180 pgk pgk EDC28_108178 EDC28_108178 EDC28_108177 EDC28_108177 EDC28_108166 EDC28_108166 glk glk EDC28_10891 EDC28_10891 EDC28_10847 EDC28_10847 ppc ppc mdh mdh EDC28_101428 EDC28_101428 EDC28_101436 EDC28_101436 EDC28_101437 EDC28_101437 EDC28_101438 EDC28_101438 EDC28_11161 EDC28_11161 pckA pckA EDC28_102327 EDC28_102327 EDC28_102294 EDC28_102294 fadI fadI EDC28_102275 EDC28_102275 accD accD folD folD EDC28_104266 EDC28_104266 eno eno acsA acsA serC serC EDC28_10425 EDC28_10425 edd edd pgl pgl zwf zwf EDC28_10421 EDC28_10421 EDC28_10420 EDC28_10420 gcvP gcvP gcvH gcvH gcvT gcvT rpiA rpiA EDC28_110152 EDC28_110152 fadB fadB EDC28_10116 EDC28_10116 EDC28_104387 EDC28_104387 EDC28_104378 EDC28_104378 ilvA ilvA EDC28_104357 EDC28_104357 EDC28_101353 EDC28_101353 EDC28_101352 EDC28_101352 fbp fbp EDC28_101123 EDC28_101123 EDC28_101110 EDC28_101110 EDC28_10195 EDC28_10195 EDC28_109173 EDC28_109173 ackA ackA EDC28_105322 EDC28_105322 EDC28_105321 EDC28_105321 EDC28_10253 EDC28_10253 EDC28_10254 EDC28_10254 pdhA pdhA EDC28_10265 EDC28_10265 EDC28_10277 EDC28_10277 EDC28_10280 EDC28_10280 EDC28_10295 EDC28_10295 GCA_001247655_01480 GCA_001247655_01480 glyA glyA EDC28_11514 EDC28_11514 EDC28_11417 EDC28_11417 EDC28_11423 EDC28_11423 GCA_001247655_01200 GCA_001247655_01200 EDC28_104286 EDC28_104286 EDC28_10610 EDC28_10610 sucD sucD sucC sucC EDC28_10637 EDC28_10637 EDC28_10638 EDC28_10638 EDC28_10640 EDC28_10640 EDC28_10641 EDC28_10641 EDC28_10642 EDC28_10642 EDC28_10643 EDC28_10643 EDC28_106102 EDC28_106102 EDC28_11087 EDC28_11087 EDC28_107246 EDC28_107246 EDC28_10744 EDC28_10744 EDC28_10745 EDC28_10745
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
gpmIUnannotated protein; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. (516 aa)
EDC28_107213Unannotated protein. (190 aa)
rnfCUnannotated protein; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfC subfamily. (955 aa)
EDC28_1036Unannotated protein. (373 aa)
accAUnannotated protein; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA. (318 aa)
prsUnannotated protein; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. (314 aa)
EDC28_103248Unannotated protein. (270 aa)
EDC28_103265Unannotated protein. (439 aa)
EDC28_103266Unannotated protein. (525 aa)
talUnannotated protein; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway. (316 aa)
pgiUnannotated protein; Belongs to the GPI family. (550 aa)
EDC28_103396Unannotated protein. (275 aa)
EDC28_103397Unannotated protein. (260 aa)
EDC28_103406Unannotated protein; Has an organic peroxide-dependent peroxidase activity. Belongs to the catalase family. (342 aa)
EDC28_10639Unannotated protein; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family. (235 aa)
EDC28_106155Unannotated protein; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. (503 aa)
EDC28_106158Unannotated protein; Belongs to the iron-sulfur dependent L-serine dehydratase family. (460 aa)
tpiAUnannotated protein; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (250 aa)
maeAUnannotated protein. (563 aa)
EDC28_106262Unannotated protein; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family. (679 aa)
EDC28_106273Unannotated protein. (496 aa)
EDC28_106274Unannotated protein; Belongs to the thiolase-like superfamily. Thiolase family. (390 aa)
EDC28_106304Unannotated protein. (453 aa)
fabVUnannotated protein; Involved in the final reduction of the elongation cycle of fatty acid synthesis (FAS II). Catalyzes the reduction of a carbon- carbon double bond in an enoyl moiety that is covalently linked to an acyl carrier protein (ACP); Belongs to the TER reductase family. (400 aa)
EDC28_108180Unannotated protein; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis. (354 aa)
pgkUnannotated protein; Belongs to the phosphoglycerate kinase family. (385 aa)
EDC28_108178Unannotated protein; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (337 aa)
EDC28_108177Unannotated protein; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate. (663 aa)
EDC28_108166Unannotated protein; Belongs to the catalase family. (481 aa)
glkUnannotated protein; Belongs to the bacterial glucokinase family. (325 aa)
EDC28_10891Unannotated protein. (288 aa)
EDC28_10847Unannotated protein; Belongs to the ribulose-phosphate 3-epimerase family. (224 aa)
ppcUnannotated protein; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle; Belongs to the PEPCase type 1 family. (870 aa)
mdhUnannotated protein; Catalyzes the reversible oxidation of malate to oxaloacetate. (313 aa)
EDC28_101428Unannotated protein; Belongs to the aconitase/IPM isomerase family. (865 aa)
EDC28_101436Unannotated protein. (474 aa)
EDC28_101437Unannotated protein; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (647 aa)
EDC28_101438Unannotated protein; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (888 aa)
EDC28_11161Unannotated protein. (288 aa)
pckAUnannotated protein; Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA. Belongs to the phosphoenolpyruvate carboxykinase (ATP) family. (533 aa)
EDC28_102327Unannotated protein. (113 aa)
EDC28_102294Unannotated protein; Belongs to the ArsC family. (119 aa)
fadIUnannotated protein; Catalyzes the final step of fatty acid oxidation in which acetyl-CoA is released and the CoA ester of a fatty acid two carbons shorter is formed. (437 aa)
EDC28_102275Unannotated protein; Catalyzes the formation of a hydroxyacyl-CoA by addition of water on enoyl-CoA. Also exhibits 3-hydroxyacyl-CoA epimerase and 3- hydroxyacyl-CoA dehydrogenase activities. In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family. (716 aa)
accDUnannotated protein; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family. (289 aa)
folDUnannotated protein; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. (285 aa)
EDC28_104266Unannotated protein. (173 aa)
enoUnannotated protein; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis. (431 aa)
acsAUnannotated protein; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. (645 aa)
serCUnannotated protein; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily. (345 aa)
EDC28_10425Unannotated protein. (210 aa)
eddUnannotated protein; Catalyzes the dehydration of 6-phospho-D-gluconate to 2- dehydro-3-deoxy-6-phospho-D-gluconate; Belongs to the IlvD/Edd family. (609 aa)
pglUnannotated protein; Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate. (234 aa)
zwfUnannotated protein; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone. (482 aa)
EDC28_10421Unannotated protein. (285 aa)
EDC28_10420Unannotated protein; Belongs to the pyruvate kinase family. (478 aa)
gcvPUnannotated protein; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. (963 aa)
gcvHUnannotated protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. (129 aa)
gcvTUnannotated protein; The glycine cleavage system catalyzes the degradation of glycine. (359 aa)
rpiAUnannotated protein; Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate. (217 aa)
EDC28_110152Unannotated protein; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (408 aa)
fadBUnannotated protein; Involved in the aerobic and anaerobic degradation of long- chain fatty acids via beta-oxidation cycle. Catalyzes the formation of 3-oxoacyl-CoA from enoyl-CoA via L-3-hydroxyacyl-CoA. It can also use D-3-hydroxyacyl-CoA and cis-3-enoyl-CoA as substrate. In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family. (716 aa)
EDC28_10116Unannotated protein. (87 aa)
EDC28_104387Unannotated protein. (130 aa)
EDC28_104378Unannotated protein; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family. (792 aa)
ilvAUnannotated protein; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. (500 aa)
EDC28_104357Unannotated protein; Belongs to the monomeric-type IDH family. (742 aa)
EDC28_101353Unannotated protein; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily. (370 aa)
EDC28_101352Unannotated protein; Serine hydrolase involved in the detoxification of formaldehyde. (273 aa)
fbpUnannotated protein; Belongs to the FBPase class 1 family. (324 aa)
EDC28_101123Unannotated protein. (293 aa)
EDC28_101110Unannotated protein; Belongs to the thiolase-like superfamily. Thiolase family. (393 aa)
EDC28_10195Unannotated protein. (485 aa)
EDC28_109173Unannotated protein. (468 aa)
ackAUnannotated protein; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (372 aa)
EDC28_105322Unannotated protein. (298 aa)
EDC28_105321Unannotated protein. (210 aa)
EDC28_10253Unannotated protein. (368 aa)
EDC28_10254Unannotated protein. (327 aa)
pdhAUnannotated protein; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3). (367 aa)
EDC28_10265Unannotated protein. (675 aa)
EDC28_10277Unannotated protein; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (478 aa)
EDC28_10280Unannotated protein; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (334 aa)
EDC28_10295Unannotated protein. (290 aa)
GCA_001247655_01480Unannotated protein. (223 aa)
glyAUnannotated protein; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (418 aa)
EDC28_11514Unannotated protein. (342 aa)
EDC28_11417Unannotated protein; Belongs to the methylenetetrahydrofolate reductase family. (300 aa)
EDC28_11423Unannotated protein. (413 aa)
GCA_001247655_01200Unannotated protein. (662 aa)
EDC28_104286Unannotated protein. (688 aa)
EDC28_10610Unannotated protein; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (305 aa)
sucDUnannotated protein; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. (290 aa)
sucCUnannotated protein; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (388 aa)
EDC28_10637Unannotated protein; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2). (399 aa)
EDC28_10638Unannotated protein. (938 aa)
EDC28_10640Unannotated protein; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily. (573 aa)
EDC28_10641Unannotated protein; Membrane-anchoring subunit of succinate dehydrogenase (SDH). (115 aa)
EDC28_10642Unannotated protein. (92 aa)
EDC28_10643Unannotated protein; Belongs to the citrate synthase family. (426 aa)
EDC28_106102Unannotated protein; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH. (510 aa)
EDC28_11087Unannotated protein. (172 aa)
EDC28_107246Unannotated protein. (498 aa)
EDC28_10744Unannotated protein; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (451 aa)
EDC28_10745Unannotated protein; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (152 aa)
Your Current Organism:
Gallaecimonas pentaromativorans
NCBI taxonomy Id: 584787
Other names: CECT 7479, DSM 21945, G. pentaromativorans, Gallaecimonas pentaromativorans Rodriguez-Blanco et al. 2010, gamma proteobacterium CEE_131, strain CEE_131
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