(12 nodes) Mixed, incl. Fructose transmembrane transport, and Phosphotransferase system, fructose IIC component network (Escherichia coli IAI39)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	fruA	Fused fructose-specific PTS enzymes: IIBcomponent; Function experimentally demonstrated in the studied species; transporter. (563 aa)
	fruK	Fructose-1-phosphate kinase; Function experimentally demonstrated in the studied species; enzyme; Belongs to the carbohydrate kinase PfkB family. (312 aa)
	fruB	Fused fructose-specific PTS enzymes: IIA component; Function experimentally demonstrated in the studied species; transporter. (376 aa)
	frwD	Enzyme IIB component of PTS; Function of strongly homologous gene; transporter. (113 aa)
	frwB	Putative enzyme IIB component of PTS; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter. (106 aa)
	frwC	Enzyme IIC component of PTS; Function of strongly homologous gene; putative transporter. (359 aa)
	CAR20287.1	Putative fructose-bisphosphate aldolase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (286 aa)
	CAR20288.1	Putative sugar aldolase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (283 aa)
	CAR20289.1	Putative phosphotransferase system, fructose-specific IIC component; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter. (363 aa)
	CAR20290.1	Putative phosphotransferase system, fructose-specific IIB subunit; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter. (104 aa)
	CAR20291.1	Putative phosphotransferase system (PTS), fructose-specific IIA component; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter. (156 aa)
	CAR20292.1	Putative PTS system transcriptional antiterminator; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative regulator. (517 aa)

Your Current Organism:

Escherichia coli IAI39

NCBI taxonomy Id: 585057
Other names: E. coli IAI39

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TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

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structured XML interaction data, according to the 'PSI-MI' data standard

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node degree of proteins in your network (given the current score cut-off)

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a flat-file format describing the coordinates and colors of nodes in the network

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CAR20287.1	CAR20288.1	ECIAI39_4180	ECIAI39_4181	Putative fructose-bisphosphate aldolase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.	Putative sugar aldolase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.	0.963
CAR20287.1	CAR20289.1	ECIAI39_4180	ECIAI39_4182	Putative fructose-bisphosphate aldolase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.	Putative phosphotransferase system, fructose-specific IIC component; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter.	0.953
CAR20287.1	CAR20290.1	ECIAI39_4180	ECIAI39_4183	Putative fructose-bisphosphate aldolase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.	Putative phosphotransferase system, fructose-specific IIB subunit; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter.	0.949
CAR20287.1	CAR20291.1	ECIAI39_4180	ECIAI39_4184	Putative fructose-bisphosphate aldolase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.	Putative phosphotransferase system (PTS), fructose-specific IIA component; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter.	0.946
CAR20287.1	CAR20292.1	ECIAI39_4180	ECIAI39_4185	Putative fructose-bisphosphate aldolase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.	Putative PTS system transcriptional antiterminator; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative regulator.	0.513
CAR20287.1	fruA	ECIAI39_4180	ECIAI39_2307	Putative fructose-bisphosphate aldolase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.	Fused fructose-specific PTS enzymes: IIBcomponent; Function experimentally demonstrated in the studied species; transporter.	0.917
CAR20287.1	fruK	ECIAI39_4180	ECIAI39_2308	Putative fructose-bisphosphate aldolase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.	Fructose-1-phosphate kinase; Function experimentally demonstrated in the studied species; enzyme; Belongs to the carbohydrate kinase PfkB family.	0.915
CAR20288.1	CAR20287.1	ECIAI39_4181	ECIAI39_4180	Putative sugar aldolase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.	Putative fructose-bisphosphate aldolase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.	0.963
CAR20288.1	CAR20289.1	ECIAI39_4181	ECIAI39_4182	Putative sugar aldolase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.	Putative phosphotransferase system, fructose-specific IIC component; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter.	0.975
CAR20288.1	CAR20290.1	ECIAI39_4181	ECIAI39_4183	Putative sugar aldolase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.	Putative phosphotransferase system, fructose-specific IIB subunit; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter.	0.968
CAR20288.1	CAR20291.1	ECIAI39_4181	ECIAI39_4184	Putative sugar aldolase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.	Putative phosphotransferase system (PTS), fructose-specific IIA component; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter.	0.964
CAR20288.1	CAR20292.1	ECIAI39_4181	ECIAI39_4185	Putative sugar aldolase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.	Putative PTS system transcriptional antiterminator; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative regulator.	0.594
CAR20288.1	fruA	ECIAI39_4181	ECIAI39_2307	Putative sugar aldolase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.	Fused fructose-specific PTS enzymes: IIBcomponent; Function experimentally demonstrated in the studied species; transporter.	0.917
CAR20288.1	fruK	ECIAI39_4181	ECIAI39_2308	Putative sugar aldolase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.	Fructose-1-phosphate kinase; Function experimentally demonstrated in the studied species; enzyme; Belongs to the carbohydrate kinase PfkB family.	0.915
CAR20289.1	CAR20287.1	ECIAI39_4182	ECIAI39_4180	Putative phosphotransferase system, fructose-specific IIC component; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter.	Putative fructose-bisphosphate aldolase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.	0.953
CAR20289.1	CAR20288.1	ECIAI39_4182	ECIAI39_4181	Putative phosphotransferase system, fructose-specific IIC component; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter.	Putative sugar aldolase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.	0.975
CAR20289.1	CAR20290.1	ECIAI39_4182	ECIAI39_4183	Putative phosphotransferase system, fructose-specific IIC component; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter.	Putative phosphotransferase system, fructose-specific IIB subunit; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter.	0.992
CAR20289.1	CAR20291.1	ECIAI39_4182	ECIAI39_4184	Putative phosphotransferase system, fructose-specific IIC component; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter.	Putative phosphotransferase system (PTS), fructose-specific IIA component; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter.	0.997
CAR20289.1	CAR20292.1	ECIAI39_4182	ECIAI39_4185	Putative phosphotransferase system, fructose-specific IIC component; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter.	Putative PTS system transcriptional antiterminator; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative regulator.	0.716
CAR20289.1	fruA	ECIAI39_4182	ECIAI39_2307	Putative phosphotransferase system, fructose-specific IIC component; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter.	Fused fructose-specific PTS enzymes: IIBcomponent; Function experimentally demonstrated in the studied species; transporter.	0.915