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exsB exsB TGAM_0020 TGAM_0020 TGAM_0372 TGAM_0372 TGAM_0512 TGAM_0512 TGAM_1854 TGAM_1854 metG metG cysS cysS gltX gltX leuS leuS ribL ribL asnB asnB lysS lysS uspA-2 uspA-2 TGAM_2110 TGAM_2110 TGAM_2112 TGAM_2112 TGAM_2130 TGAM_2130 TGAM_2143 TGAM_2143 nadE nadE guaA_C guaA_C tyrS tyrS TGAM_1102 TGAM_1102 nadM nadM TGAM_1193 TGAM_1193 thiI-1 thiI-1 thiI-2 thiI-2 TGAM_0542 TGAM_0542 ileS ileS valS valS argS argS TGAM_0001 TGAM_0001 TGAM_0150 TGAM_0150 trpS trpS coaD coaD uspA-1 uspA-1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
exsBTranscription regulator, putative, ExsB family (ExsB); Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. (239 aa)
TGAM_0020PP-loop ATPase, YdaO-type. (325 aa)
TGAM_0372PP-loop ATPase, MJ1638-related. (245 aa)
TGAM_05123'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase), containing one PUA domain and 2 4Fe-4S binding domains. (634 aa)
TGAM_1854ATP-binding protein, PP-loop superfamily. (244 aa)
metGMethionyl-tRNA synthetase (metG); Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. (739 aa)
cysSCysteinyl-tRNA synthetase (cysS). (476 aa)
gltXGlutamyl-tRNA synthetase (gltX); Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu). (571 aa)
leuSLeucyl-tRNA synthetase (leuS); Belongs to the class-I aminoacyl-tRNA synthetase family. (968 aa)
ribLCytidylyltransferase; Catalyzes the transfer of the AMP portion of ATP to flavin mononucleotide (FMN) to produce flavin adenine dinucleotide (FAD) coenzyme. (151 aa)
asnBAsparagine synthase (glutamine-hydrolyzing) (asnB). (479 aa)
lysSLysyl-tRNA synthetase (lysS); Belongs to the class-I aminoacyl-tRNA synthetase family. (525 aa)
uspA-2Universal stress DNA-binding protein (UspA). (151 aa)
TGAM_2110Conserved hypothetical protein. (186 aa)
TGAM_2112Phosphoadenosine phosphosulfate (PAPS) reductase related protein. (420 aa)
TGAM_2130PP-loop ATPase, YdaO-type. (304 aa)
TGAM_2143Asparagine synthetase related protein. (528 aa)
nadENH(3)-dependent NAD synthetase (nadE); Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source. (254 aa)
guaA_CGMP synthase [glutamine-hydrolyzing] pyrophosphatase subunit (C terminal domain) (guaA_C); Catalyzes the synthesis of GMP from XMP. (311 aa)
tyrSTyrosyl-tRNA synthetase (tyrS); Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr); Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 4 subfamily. (375 aa)
TGAM_1102Predicted ATPase of the PP-loop superfamily. (262 aa)
nadMNicotinamide-nucleotide adenylyltransferase (nadM). (187 aa)
TGAM_1193ATPase, putative, PP-loop superfamily. (206 aa)
thiI-1Thiamine biosynthesis protein (ThiI); Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS. (380 aa)
thiI-2Thiamin biosynthesis protein (thiI); Does not contain THUMP domain in N-terminus as tg1481. (197 aa)
TGAM_0542N-type ATP pyrophosphatase, putative. (213 aa)
ileSIsoleucyl-tRNA synthetase (ileS); Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily. (1066 aa)
valSValyl-tRNA synthetase (valS); Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA- dependent manner; Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 2 subfamily. (888 aa)
argSArginyl-tRNA synthetase (argS); Belongs to the class-I aminoacyl-tRNA synthetase family. (640 aa)
TGAM_0001Putative asparagine synthase, glutamine-hydrolyzing. (617 aa)
TGAM_0150P-loop ATPase, MJ1599 type. (276 aa)
trpSTryptophanyl-tRNA synthetase (trpS); Catalyzes the attachment of tryptophan to tRNA(Trp). (384 aa)
coaDPhosphopantetheine adenylyltransferase (coaD); Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the eukaryotic CoaD family. (159 aa)
uspA-1Universal stress protein (UspA). (281 aa)
Your Current Organism:
Thermococcus gammatolerans
NCBI taxonomy Id: 593117
Other names: T. gammatolerans EJ3, Thermococcus gammatolerans EJ3, Thermococcus gammatolerans str. EJ3, Thermococcus gammatolerans strain EJ3
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