(35 nodes) Lysine degradation network (Agaricus bisporus)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	K5VK66_AGABU	Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (526 aa)
	K5VKB7_AGABU	Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family. (504 aa)
	K5VLQ1_AGABU	Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (527 aa)
	K5VSR3_AGABU	Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family. (501 aa)
	K5VVC1_AGABU	Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family. (534 aa)
	K5VZN4_AGABU	Succinate-semialdehyde dehydrogenase. (528 aa)
	K5W2W5_AGABU	DAO domain-containing protein. (401 aa)
	K5W3S9_AGABU	Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family. (504 aa)
	K5WI14_AGABU	Uncharacterized protein; Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. SET2 subfamily. (881 aa)
	K5WJ18_AGABU	Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family. (506 aa)
	K5WWP9_AGABU	Transket_pyr domain-containing protein. (951 aa)
	K5WZ39_AGABU	Uncharacterized protein; Belongs to the enoyl-CoA hydratase/isomerase family. (297 aa)
	K5X036_AGABU	Uncharacterized protein. (420 aa)
	K5X1X4_AGABU	Uncharacterized protein. (643 aa)
	K5X2H6_AGABU	Lipoyl-binding domain-containing protein. (432 aa)
	K5X367_AGABU	Uncharacterized protein. (603 aa)
	K5X3F8_AGABU	Uncharacterized protein. (990 aa)
	K5X3G1_AGABU	Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family. (500 aa)
	K5X3J1_AGABU	Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family. (503 aa)
	K5X3K2_AGABU	Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family. (507 aa)
	K5X3K8_AGABU	Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family. (502 aa)
	K5X887_AGABU	Uncharacterized protein. (443 aa)
	K5X8L3_AGABU	Dihydrolipoyl dehydrogenase. (508 aa)
	K5XBA3_AGABU	Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family. (505 aa)
	K5XCL3_AGABU	SET domain-containing protein. (1017 aa)
	K5XDL6_AGABU	Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family. (502 aa)
	K5XG22_AGABU	Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family. (508 aa)
	K5XIP8_AGABU	Histone-lysine N-methyltransferase, H3 lysine-79 specific; Histone methyltransferase that specifically methylates histone H3 to form H3K79me. This methylation is required for telomere silencing and for the pachytene checkpoint during the meiotic cell cycle by allowing the recruitment of RAD9 to double strand breaks. Nucleosomes are preferred as substrate compared to free histones. (438 aa)
	K5XJT2_AGABU	Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (491 aa)
	K5XK34_AGABU	Saccharopine dehydrogenase [NAD(+), L-lysine-forming]; Belongs to the AlaDH/PNT family. (367 aa)
	K5XMF0_AGABU	PABS domain-containing protein; Belongs to the spermidine/spermine synthase family. (759 aa)
	K5XQR9_AGABU	AlaDh_PNT_N domain-containing protein. (1004 aa)
	K5XRJ5_AGABU	Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family. (502 aa)
	K5XS67_AGABU	SET domain-containing protein. (373 aa)
	K5XYC4_AGABU	Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family. (411 aa)

Your Current Organism:

Agaricus bisporus

NCBI taxonomy Id: 597362
Other names: A. bisporus var. burnettii JB137-S8, Agaricus bisporus var. burnettii JB137-S8

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
K5VK66_AGABU	K5X2H6_AGABU	K5VK66	K5X2H6	Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.	Lipoyl-binding domain-containing protein.	0.400
K5VK66_AGABU	K5XYC4_AGABU	K5VK66	K5XYC4	Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.	Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family.	0.410
K5VLQ1_AGABU	K5X2H6_AGABU	K5VLQ1	K5X2H6	Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.	Lipoyl-binding domain-containing protein.	0.400
K5VLQ1_AGABU	K5XYC4_AGABU	K5VLQ1	K5XYC4	Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.	Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family.	0.410
K5VVC1_AGABU	K5WWP9_AGABU	K5VVC1	K5WWP9	Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family.	Transket_pyr domain-containing protein.	0.409
K5VVC1_AGABU	K5WZ39_AGABU	K5VVC1	K5WZ39	Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family.	Uncharacterized protein; Belongs to the enoyl-CoA hydratase/isomerase family.	0.443
K5VVC1_AGABU	K5XMF0_AGABU	K5VVC1	K5XMF0	Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family.	PABS domain-containing protein; Belongs to the spermidine/spermine synthase family.	0.934
K5VVC1_AGABU	K5XQR9_AGABU	K5VVC1	K5XQR9	Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family.	AlaDh_PNT_N domain-containing protein.	0.934
K5VVC1_AGABU	K5XYC4_AGABU	K5VVC1	K5XYC4	Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family.	Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family.	0.403
K5VZN4_AGABU	K5XYC4_AGABU	K5VZN4	K5XYC4	Succinate-semialdehyde dehydrogenase.	Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family.	0.436
K5W2W5_AGABU	K5X8L3_AGABU	K5W2W5	K5X8L3	DAO domain-containing protein.	Dihydrolipoyl dehydrogenase.	0.542
K5WI14_AGABU	K5X1X4_AGABU	K5WI14	K5X1X4	Uncharacterized protein; Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. SET2 subfamily.	Uncharacterized protein.	0.915
K5WI14_AGABU	K5X367_AGABU	K5WI14	K5X367	Uncharacterized protein; Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. SET2 subfamily.	Uncharacterized protein.	0.924
K5WI14_AGABU	K5X3F8_AGABU	K5WI14	K5X3F8	Uncharacterized protein; Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. SET2 subfamily.	Uncharacterized protein.	0.924
K5WI14_AGABU	K5X887_AGABU	K5WI14	K5X887	Uncharacterized protein; Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. SET2 subfamily.	Uncharacterized protein.	0.915
K5WI14_AGABU	K5XCL3_AGABU	K5WI14	K5XCL3	Uncharacterized protein; Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. SET2 subfamily.	SET domain-containing protein.	0.960
K5WI14_AGABU	K5XIP8_AGABU	K5WI14	K5XIP8	Uncharacterized protein; Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. SET2 subfamily.	Histone-lysine N-methyltransferase, H3 lysine-79 specific; Histone methyltransferase that specifically methylates histone H3 to form H3K79me. This methylation is required for telomere silencing and for the pachytene checkpoint during the meiotic cell cycle by allowing the recruitment of RAD9 to double strand breaks. Nucleosomes are preferred as substrate compared to free histones.	0.969
K5WI14_AGABU	K5XS67_AGABU	K5WI14	K5XS67	Uncharacterized protein; Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. SET2 subfamily.	SET domain-containing protein.	0.926
K5WWP9_AGABU	K5VVC1_AGABU	K5WWP9	K5VVC1	Transket_pyr domain-containing protein.	Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family.	0.409
K5WWP9_AGABU	K5X036_AGABU	K5WWP9	K5X036	Transket_pyr domain-containing protein.	Uncharacterized protein.	0.923