STRINGSTRING
GGA3 GGA3 ERAS ERAS ARF6 ARF6 ENSCSAP00000018444 ENSCSAP00000018444 ENSCSAP00000018065 ENSCSAP00000018065 ENSCSAP00000018022 ENSCSAP00000018022 LOC103232070 LOC103232070 ENSCSAP00000017765 ENSCSAP00000017765 ENSCSAP00000017575 ENSCSAP00000017575 EPS15 EPS15 DOCK7 DOCK7 COL24A1 COL24A1 COL11A1 COL11A1 RAP1A RAP1A NRAS NRAS CSDE1 CSDE1 SHC1 SHC1 HGS HGS PTPN11 PTPN11 CBL CBL TNS4 TNS4 STAT3 STAT3 GAB1 GAB1 RAB4B RAB4B FNDC3A FNDC3A LAMA3 LAMA3 ENSCSAP00000013601 ENSCSAP00000013601 PTPN2 PTPN2 RAP1B RAP1B SPINT2 SPINT2 SH3GL3 SH3GL3 ITGA2 ITGA2 LAMA2 LAMA2 STAM2 STAM2 HGFAC HGFAC PIK3R1 PIK3R1 LAMA5 LAMA5 TNS3 TNS3 LAMA4 LAMA4 COL5A1 COL5A1 LAMB3 LAMB3 LAMB2 LAMB2 PTPN1 PTPN1 RAPGEF1 RAPGEF1 LAMC3 LAMC3 SH3KBP1 SH3KBP1 RPS27A RPS27A CRK CRK SRC SRC CRKL CRKL MEGF11 MEGF11 PIK3CA PIK3CA FNDC3B FNDC3B COL1A2 COL1A2 STAM STAM LAMC2 LAMC2 LAMC1 LAMC1 COL27A1 COL27A1 COL3A1 COL3A1 COL5A2 COL5A2 SOS1 SOS1 HGF HGF LRIG1 LRIG1 ITGB1 ITGB1 LAMB1 LAMB1 HRAS HRAS USP8 USP8 MET MET RAB4A RAB4A SH3GL1 SH3GL1 PTK2 PTK2 COL11A2 COL11A2 SH3GL2 SH3GL2 FN1 FN1 TNS1 TNS1 KRAS KRAS SPINT1 SPINT1 RANBP9 RANBP9 COL5A3 COL5A3 COL2A1 COL2A1 PTPRJ PTPRJ UBA52 UBA52 COL1A1 COL1A1 ITGA3 ITGA3 GRB2 GRB2 HPN HPN
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
GGA3Golgi associated, gamma adaptin ear containing, ARF binding protein 3. (723 aa)
ERASES cell expressed Ras. (233 aa)
ARF6ADP ribosylation factor 6; Belongs to the small GTPase superfamily. Arf family. (175 aa)
ENSCSAP00000018444Ubiquitin-like domain-containing protein. (127 aa)
ENSCSAP00000018065annotation not available (184 aa)
ENSCSAP00000018022Uncharacterized protein. (184 aa)
LOC103232070Uncharacterized protein. (620 aa)
ENSCSAP00000017765Ubiquitin-like domain-containing protein. (155 aa)
ENSCSAP00000017575Ubiquitin-like domain-containing protein. (156 aa)
EPS15Epidermal growth factor receptor pathway substrate 15. (897 aa)
DOCK7Dedicator of cytokinesis 7; Belongs to the DOCK family. (2129 aa)
COL24A1Collagen type XXIV alpha 1 chain. (1714 aa)
COL11A1Collagen type XI alpha 1 chain. (1806 aa)
RAP1ARAP1A, member of RAS oncogene family. (184 aa)
NRASNRAS proto-oncogene, GTPase. (189 aa)
CSDE1Cold shock domain containing E1. (844 aa)
SHC1SHC adaptor protein 1. (474 aa)
HGSHepatocyte growth factor-regulated tyrosine kinase substrate; Involved in intracellular signal transduction mediated by cytokines and growth factors. When associated with STAM, it suppresses DNA signaling upon stimulation by IL-2 and GM-CSF. Could be a direct effector of PI3-kinase in vesicular pathway via early endosomes and may regulate trafficking to early and late endosomes by recruiting clathrin. May concentrate ubiquitinated receptors within clathrin- coated regions. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with STAM (E [...] (777 aa)
PTPN11Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (596 aa)
CBLCbl proto-oncogene. (907 aa)
TNS4Tensin 4. (712 aa)
STAT3Signal transducer and activator of transcription. (770 aa)
GAB1GRB2 associated binding protein 1. (751 aa)
RAB4BUncharacterized protein. (213 aa)
FNDC3AFibronectin type III domain containing 3A. (1198 aa)
LAMA3Laminin subunit alpha 3. (3333 aa)
ENSCSAP00000013601Uncharacterized protein. (637 aa)
PTPN2Protein tyrosine phosphatase non-receptor type 2. (298 aa)
RAP1BUncharacterized protein. (184 aa)
SPINT2Serine peptidase inhibitor, Kunitz type 2. (252 aa)
SH3GL3SH3 domain containing GRB2 like 3, endophilin A3. (347 aa)
ITGA2Integrin subunit alpha 2; Belongs to the integrin alpha chain family. (1180 aa)
LAMA2Laminin subunit alpha 2. (3147 aa)
STAM2Signal transducing adaptor molecule 2. (525 aa)
HGFACHGF activator. (538 aa)
PIK3R1Phosphoinositide-3-kinase regulatory subunit 1. (724 aa)
LAMA5Laminin subunit alpha 5. (3694 aa)
TNS3Tensin 3. (1557 aa)
LAMA4Laminin subunit alpha 4. (1816 aa)
COL5A1Collagen type V alpha 1 chain. (1641 aa)
LAMB3Laminin subunit beta 3. (1172 aa)
LAMB2Laminin subunit beta 2. (1798 aa)
PTPN1Tyrosine-protein phosphatase non-receptor type. (435 aa)
RAPGEF1Rap guanine nucleotide exchange factor 1. (1264 aa)
LAMC3Uncharacterized protein. (820 aa)
SH3KBP1SH3 domain containing kinase binding protein 1. (690 aa)
RPS27AUbiquitin-like domain-containing protein. (156 aa)
CRKCRK proto-oncogene, adaptor protein. (204 aa)
SRCTyrosine-protein kinase. (633 aa)
CRKLCRK like proto-oncogene, adaptor protein. (303 aa)
MEGF11Multiple EGF like domains 11. (1015 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
FNDC3BFibronectin type III domain containing 3B. (1204 aa)
COL1A2Collagen type I alpha 2 chain. (1274 aa)
STAMSignal transducing adaptor molecule. (540 aa)
LAMC2Laminin subunit gamma 2. (1193 aa)
LAMC1Laminin subunit gamma 1. (1573 aa)
COL27A1Collagen type XXVII alpha 1 chain. (1860 aa)
COL3A1Collagen type III alpha 1 chain. (878 aa)
COL5A2Collagen type V alpha 2 chain. (1499 aa)
SOS1SOS Ras/Rac guanine nucleotide exchange factor 1. (1333 aa)
HGFHepatocyte growth factor; Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization. Belongs to the peptidase S1 family. Plasminogen subfamily. (728 aa)
LRIG1Leucine rich repeats and immunoglobulin like domains 1. (1088 aa)
ITGB1Integrin beta; Belongs to the integrin beta chain family. (798 aa)
LAMB1Laminin subunit beta 1. (1786 aa)
HRASHRas proto-oncogene, GTPase. (189 aa)
USP8Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (960 aa)
METMET proto-oncogene, receptor tyrosine kinase. (1381 aa)
RAB4ARAB4A, member RAS oncogene family. (218 aa)
SH3GL1SH3 domain containing GRB2 like 1, endophilin A2. (396 aa)
PTK2Protein tyrosine kinase 2; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1038 aa)
COL11A2Collagen type XI alpha 2 chain. (1650 aa)
SH3GL2SH3 domain containing GRB2 like 2, endophilin A1. (317 aa)
FN1Fibronectin 1. (2265 aa)
TNS1Tensin 1. (1862 aa)
KRASKRAS proto-oncogene, GTPase. (189 aa)
SPINT1Serine peptidase inhibitor, Kunitz type 1. (513 aa)
RANBP9RAN binding protein 9. (500 aa)
COL5A3Collagen type V alpha 3 chain. (1749 aa)
COL2A1Collagen type II alpha 1 chain. (1488 aa)
PTPRJProtein tyrosine phosphatase receptor type J. (1333 aa)
UBA52Ubiquitin A-52 residue ribosomal protein fusion product 1. (128 aa)
COL1A1Collagen type I alpha 1 chain. (1464 aa)
ITGA3Integrin subunit alpha 3; Belongs to the integrin alpha chain family. (1049 aa)
GRB2Growth factor receptor bound protein 2. (217 aa)
HPNHepsin; Belongs to the peptidase S1 family. (417 aa)
Your Current Organism:
Chlorocebus sabaeus
NCBI taxonomy Id: 60711
Other names: C. sabaeus, Cercopithecus aethiops sabaeus, Cercopithecus sabaeus, Cercopithecus sabeus, Chlorocebus aethiops sabaeus, Chlorocebus aethiops sabeus, Chlorocebus sabeus, green monkey
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