Your Input: | |
| | Y116F11A.1 | ATP-dependent DNA helicase; Belongs to the helicase family. (202 aa) |
| | his-48 | Probable histone H2B 4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (123 aa) |
| | his-46 | Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (103 aa) |
| | xnp-1 | Transcriptional regulator ATRX homolog; Required for embryonic development and gonadogenesis. Also, functions redundantly with the transcriptional repressor lin-35 to regulate somatic gonad development. (1359 aa) |
| | C11G6.2 | ATP-dependent DNA helicase; Belongs to the helicase family. (169 aa) |
| | nola-3 | Putative H/ACA ribonucleoprotein complex subunit 3; Required for ribosome biogenesis. Part of a complex which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Pseudouridine ('psi') residues may serve to stabilize the conformation of rRNAs (By similarity). (64 aa) |
| | ruvb-1 | RuvB-like 1; Possesses single-stranded DNA-stimulated ATPase and ATP dependent DNA helicase (3' to 5') activity suggesting a role in nuclear processes such as recombination and transcription (By similarity). May participate in several chromatin remodeling complexes that mediate the ATP-dependent exchange of histones and remodel chromatin by shifting nucleosomes (By similarity). Involvement in these complexes is likely required for transcriptional activation of selected genes and DNA repair in response to DNA damage (By similarity). Involved in the Ce- Tor signaling pathway whereby it i [...] (476 aa) |
| | pph-6 | Serine/threonine-protein phosphatase 6 catalytic subunit; Catalytic subunit of protein phosphatase 6 (PP6) (By similarity). In complex with saps-1, promotes actomyosin contractility during cytokinesis by regulating the organization of cortical non- muscle myosin II nmy-2 and thus contributing to correct spindle positioning. Also required for the proper generation of pulling forces on spindle poles during anaphase by regulating the cortical localization of gpr-1, gpr-2 and lin-5. Belongs to the PPP phosphatase family. PP-6 (PP-V) subfamily. (331 aa) |
| | C39E9.12 | SAP domain-containing protein. (409 aa) |
| | rfc-3 | RFC (DNA replication factor) family. (354 aa) |
| | his-41 | Probable histone H2B 3; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (123 aa) |
| | his-37 | Histone H4. (103 aa) |
| | rfc-1 | Replication factor C subunit 1. (839 aa) |
| | trt-1 | Telomerase reverse transcriptase; Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. It elongates telomeres. It is a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme. (561 aa) |
| | his-54 | Histone H2B 2; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (123 aa) |
| | his-52 | Histone H2B 2. (123 aa) |
| | his-50 | Histone H4. (103 aa) |
| | glo-4 | X-linked retinitis pigmentosa GTPase regulator homolog; Could be a guanine-nucleotide releasing factor for glo-1. May play a role in gut granule biogenesis. Regulates axon termination in PLM and ALM neurons. (1386 aa) |
| | F08F1.9 | CYCLIN domain-containing protein; Belongs to the cyclin family. (130 aa) |
| | his-44 | Histone H2B 1; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (122 aa) |
| | F10C2.4 | DNA polymerase delta catalytic subunit; Possesses two enzymatic activities: DNA synthesis (polymerase) and an exonucleolytic activity that degrades single stranded DNA in the 3'- to 5'-direction. Required with its accessory proteins (proliferating cell nuclear antigen (PCNA) and replication factor C (RFC) or activator 1) for leading strand synthesis. Also involved in completing Okazaki fragments initiated by the DNA polymerase alpha/primase complex (By similarity). (1081 aa) |
| | F11C3.1 | ATP-dependent DNA helicase. (431 aa) |
| | F12F6.7 | Probable DNA polymerase delta small subunit; The function of the small subunit is not yet clear; Belongs to the DNA polymerase delta/II small subunit family. (451 aa) |
| | his-31 | Histone H4. (103 aa) |
| | his-34 | Histone H2B 1. (122 aa) |
| | rpa-1 | Probable replication factor A 73 kDa subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (655 aa) |
| | wrn-1 | Probable Werner syndrome ATP-dependent helicase homolog 1; Essential for the formation of DNA replication focal centers; stably associates with foci elements generating binding sites for RP-A. Exhibits a magnesium-dependent ATP-dependent DNA-helicase activity. May be involved in the control of genomic stability (By similarity). (1056 aa) |
| | his-64 | Histone H4. (103 aa) |
| | rfc-4 | Replication factor C subunit 4; The elongation of primed DNA templates by DNA polymerase delta and epsilon requires the action of the accessory proteins PCNA and activator 1. This subunit may be involved in the elongation of the multiprimed DNA template (By similarity). (334 aa) |
| | F33H12.6 | ATP-dependent DNA helicase; Belongs to the helicase family. (1360 aa) |
| | his-29 | Histone H2B 1. (122 aa) |
| | isw-1 | Chromatin-remodeling complex ATPase chain isw-1; Energy-transducing component of a NURF-like (nucleosome- remodeling factor-like) complex, which would catalyze ATP-dependent nucleosome sliding and facilitate transcription of chromatin (Probable). Involved in vulval cell fates. Belongs to the SNF2/RAD54 helicase family. ISWI subfamily. (1009 aa) |
| | dna-2 | Yeast DNA helicase/endonuclease family. (1069 aa) |
| | F44B9.8 | Probable replication factor C subunit 5; The elongation of primed DNA templates by DNA polymerase delta and epsilon requires the action of the accessory proteins proliferating cell nuclear antigen (PCNA) and activator 1. (368 aa) |
| | his-8 | Histone H2B 2. (123 aa) |
| | his-39 | Histone domain-containing protein; Belongs to the histone H2B family. (67 aa) |
| | his-5 | Histone H4. (103 aa) |
| | F52G3.3 | ATP-dependent DNA helicase. (807 aa) |
| | F52G3.4 | annotation not available (1009 aa) |
| | his-56 | Histone H4. (103 aa) |
| | his-58 | Probable histone H2B 4. (123 aa) |
| | his-60 | Histone H4. (103 aa) |
| | his-62 | Probable histone H2B 4. (123 aa) |
| | pri-1 | DNA primase small subunit; DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments made during discontinuous DNA replication. (410 aa) |
| | rfc-2 | AAA domain-containing protein. (334 aa) |
| | F59H6.5 | ATP-dependent DNA helicase; Belongs to the helicase family. (1486 aa) |
| | cya-2 | CYCLIN domain-containing protein; Belongs to the cyclin family. (123 aa) |
| | his-66 | Probable histone H2B 4. (123 aa) |
| | K01G5.5 | Putative H/ACA ribonucleoprotein complex subunit 4; Plays a central role in ribosomal RNA processing. Probable catalytic subunit of H/ACA small nucleolar ribonucleoprotein (H/ACA snoRNP) complex, which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Pseudouridine ('psi') residues may serve to stabilize the conformation of rRNAs (By similarity); Belongs to the pseudouridine synthase TruB family. (445 aa) |
| | his-38 | Histone H4. (103 aa) |
| | knl-2 | Kinetochore null protein 2; Required for the recruitment of hcp-3, hcp-4, knl-1, bub-1 and lin-53 to kinetochores, kinetochore assembly, chromosome condensation and chromosome segregation in meiosis and mitosis. (877 aa) |
| | his-18 | Histone H4. (103 aa) |
| | his-22 | Histone H2B 2. (123 aa) |
| | his-28 | Histone H4. (103 aa) |
| | his-20 | Histone H2B 2. (123 aa) |
| | lin-53 | Probable histone-binding protein lin-53; Core histone-binding subunit that may target chromatin assembly factors, chromatin remodeling factors and histone deacetylases to their histone substrates in a manner that is regulated by nucleosomal DNA (By similarity). Required for hcp-3 and his-1 stabilization, localization of hcp-3 to centromeres and for proper chromosome segregation. Synthetic multivulva class B (synMuvB) protein. SynMuvB proteins are required to repress the induction of vulval development by Ras signaling and probably act by forming the multiprotein DRM complex that repres [...] (417 aa) |
| | sdz-24 | OB domain-containing protein. (236 aa) |
| | ctf-18 | AAA domain-containing protein. (850 aa) |
| | dscc-1 | Dna (DNA) replication and Sister Chromatid Cohesion. (443 aa) |
| | div-1 | DNA polymerase alpha subunit B; May play an essential role at the early stage of chromosomal DNA replication by coupling the polymerase alpha/primase complex to the cellular replication machinery. Required for the distribution of pie-1 in cell divsion. (581 aa) |
| | R03H10.6 | REPA_OB_2 domain-containing protein. (324 aa) |
| | R03H10.7 | REPA_OB_2 domain-containing protein. (359 aa) |
| | htz-1 | Histone H2A.V; Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post- translational modifications of histones, also called histone code, and nucleosome remodeling (By similarity). Required to maintain non-distal tip cell (DTC) fate of somatic gonadal [...] (140 aa) |
| | him-6 | Bloom syndrome protein homolog; Participates in DNA replication and repair (By similarity). Exhibits a magnesium-dependent ATP-dependent DNA-helicase activity that unwinds single- and double-stranded DNA in a 3'-5' direction (By similarity). Negatively regulates sister chromatid exchange (SCE) ; Belongs to the helicase family. RecQ subfamily. (988 aa) |
| | T09B4.6 | Uncharacterized protein. (119 aa) |
| | his-4 | Histone H2B 2. (123 aa) |
| | his-1 | Histone H4. (103 aa) |
| | ctf-8 | Chromosome Transmission Fidelity factor homolog. (111 aa) |
| | ruvb-2 | RuvB-like 2; Possesses single-stranded DNA-stimulated ATPase and ATP- dependent DNA helicase (5' to 3') activity suggesting a role in nuclear processes such as recombination and transcription (By similarity). May participate in several chromatin remodeling complexes that mediate the ATP-dependent exchange of histones and remodel chromatin by shifting nucleosomes (By similarity). Involvement in these complexes is likely required for transcriptional activation of selected genes and DNA repair in response to DNA damage (By similarity). Has a role in gonadal development. Involved in the en [...] (448 aa) |
| | his-67 | Histone H4. (103 aa) |
| | T24C4.5 | DNA primase; Belongs to the eukaryotic-type primase small subunit family. (318 aa) |
| | pri-2 | DNA primase large subunit; DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments made during discontinuous DNA replication. (503 aa) |
| | pcn-1 | Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (263 aa) |
| | W05G11.2 | Cyclin N-terminal domain-containing protein. (192 aa) |
| | Y104H12D.2 | Uncharacterized protein. (327 aa) |
| | Y104H12D.4 | Uncharacterized protein. (107 aa) |
| | tcab-1 | Telomerase CAjal Body protein 1 homolog. (449 aa) |
| | Y16E11A.2 | ATP-dependent DNA helicase; Belongs to the helicase family. (1466 aa) |
| | pif-1 | ATP-dependent DNA helicase PIF1; DNA-dependent ATPase and 5'-3' DNA helicase required for the maintenance of both mitochondrial and nuclear genome stability. (677 aa) |
| | Y46B2A.2 | ATP-dependent DNA helicase; Belongs to the helicase family. (1365 aa) |
| | pola-1 | DNA polymerase. (1456 aa) |
| | crn-1 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] (382 aa) |
| | Y48A5A.1 | Protein SHQ1 homolog; Required for the quantitative accumulation of H/ACA ribonucleoproteins (RNPs). (431 aa) |
| | Y48A6B.3 | Putative H/ACA ribonucleoprotein complex subunit 2-like protein; Required for ribosome biogenesis. Part of a complex which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Pseudouridine ('psi') residues may serve to stabilize the conformation of rRNAs (By similarity). (163 aa) |
| | Y53F4B.26 | Uncharacterized protein. (152 aa) |
| | Y53F4B.7 | annotation not available (152 aa) |
| | Y66H1A.4 | Probable H/ACA ribonucleoprotein complex subunit 1-like protein; Required for ribosome biogenesis. Part of a complex which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Pseudouridine ('psi') residues may serve to stabilize the conformation of rRNAs (By similarity). (244 aa) |
| | his-26 | Histone H4. (103 aa) |
| | his-10 | Histone H4. (103 aa) |
| | his-11 | Histone H2B 1. (122 aa) |
| | his-14 | Histone H4. (103 aa) |
| | his-15 | Histone H2B 1. (122 aa) |
| | ZK250.9 | ATP-dependent DNA helicase. (1466 aa) |
| | cya-1 | G2/mitotic-specific cyclin-A1; Involved in the control of the cell cycle after S phase. May bind to and activate cdk-1 and/or cdk-2 to promote cell cycle progression. Necessary for embryogenesis. Belongs to the cyclin family. Cyclin AB subfamily. (485 aa) |
| | ZK678.3 | annotation not available (163 aa) |
