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SVI_3752 SVI_3752 kdtA kdtA kdkA kdkA rfbD rfbD SVI_0100 SVI_0100 SVI_0101 SVI_0101 SVI_0104 SVI_0104 SVI_0109 SVI_0109 SVI_0373 SVI_0373 SVI_0390 SVI_0390 SVI_0418 SVI_0418 htrB htrB kdsB-1 kdsB-1 SVI_0865 SVI_0865 adhB adhB lpxD lpxD fabZ fabZ lpxA lpxA lpxB lpxB SVI_1259 SVI_1259 SVI_1467 SVI_1467 nudD nudD SVI_1474 SVI_1474 SVI_1476 SVI_1476 SVI_1483 SVI_1483 SVI_1484 SVI_1484 SVI_1487 SVI_1487 SVI_1493 SVI_1493 SVI_1496 SVI_1496 SVI_1508 SVI_1508 SVI_1551 SVI_1551 SVI_1553 SVI_1553 lpxC lpxC SVI_1555 SVI_1555 SVI_1559 SVI_1559 SVI_1562 SVI_1562 SVI_1563 SVI_1563 SVI_1567 SVI_1567 SVI_1568 SVI_1568 SVI_4097 SVI_4097 kdsB-2 kdsB-2 SVI_1928 SVI_1928 SVI_1929 SVI_1929 lapA lapA lapB lapB SVI_2311 SVI_2311 lpxM lpxM lpxK lpxK glmU glmU lpxH lpxH kdsA kdsA SVI_3503 SVI_3503
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SVI_3752dTDP-4-dehydrorhamnose reductase, putative; Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose; Belongs to the dTDP-4-dehydrorhamnose reductase family. (306 aa)
kdtA3-deoxy-D-manno-octulosonic-acid (KDO) transferase; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family. (422 aa)
kdkA3-deoxy-D-manno-octulosonic acid (KDO) kinase; Catalyzes the ATP-dependent phosphorylation of the 3-deoxy-D- manno-octulosonic acid (Kdo) residue in Kdo-lipid IV(A) at the 4-OH position; Belongs to the protein kinase superfamily. KdkA/RfaP family. (241 aa)
rfbDdTDP-4-dehydrorhamnose reductase; Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose; Belongs to the dTDP-4-dehydrorhamnose reductase family. (288 aa)
SVI_0100Glycosyl transferase, putative. (268 aa)
SVI_0101Heptosyl transferase, glycosyltransferase family 9 protein. (347 aa)
SVI_0104Conserved hypothetical protein. (392 aa)
SVI_0109Conserved hypothetical protein. (335 aa)
SVI_0373Acyltransferase family protein. (600 aa)
SVI_0390Conserved hypothetical protein. (289 aa)
SVI_0418Conserved hypothetical protein; Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8- phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate; Belongs to the KdsC family. (185 aa)
htrBLipid A biosynthesis lauroyl acyltransferase; Catalyzes the transfer of laurate from lauroyl-acyl carrier protein (ACP) to Kdo(2)-lipid IV(A) to form Kdo(2)-(lauroyl)-lipid IV(A). (308 aa)
kdsB-13-deoxy-manno-octulosonate cytidylyltransferase; Activates KDO8N (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in the Shewanella genus. Belongs to the KdsB family. (270 aa)
SVI_0865Conserved hypothetical protein. (318 aa)
adhBAlcohol dehydrogenase II. (382 aa)
lpxDUDP-3-O-(3-hydroxymyristoyl) glucosamine N-acyltransferase; Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3- hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. Belongs to the transferase hexapeptide repeat family. LpxD subfamily. (341 aa)
fabZ(3R)-hydroxymyristoyl-(acyl-carrier-protein) dehydratase; Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs. (152 aa)
lpxAacyl-(acyl-carrier-protein)--UDP-N- acetylglucosamine O-acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. (255 aa)
lpxBLipid A disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. (381 aa)
SVI_1259Acyltransferase family protein. (413 aa)
SVI_1467Chain length determinant protein. (319 aa)
nudDGDP-mannose mannosyl hydrolase. (163 aa)
SVI_1474Polysaccharide biosynthesis family protein. (414 aa)
SVI_1476Glycosyl transferase, putative. (380 aa)
SVI_1483Acetyltransferase, putative. (149 aa)
SVI_1484Aminotransferase, putative; Belongs to the DegT/DnrJ/EryC1 family. (367 aa)
SVI_1487Acyltransferase family protein. (588 aa)
SVI_1493Hypothetical protein. (141 aa)
SVI_1496Polysaccharide biosynthesis protein. (644 aa)
SVI_1508Hypothetical protein. (530 aa)
SVI_1551Glycosyl transferase, putative. (410 aa)
SVI_1553Glycosyl transferase, group 1 family protein. (401 aa)
lpxCUDP-3-O-(3-hydroxymyristoyl) N-acetylglucosamine deacetylase; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis; Belongs to the LpxC family. (306 aa)
SVI_1555Hypothetical protein. (451 aa)
SVI_1559Conserved hypothetical protein. (487 aa)
SVI_1562Glycosyl transferase, group 1 family protein. (390 aa)
SVI_1563Glycosyl transferase, group 1 family protein. (408 aa)
SVI_1567Glycosyl transferase, group 1 family protein. (426 aa)
SVI_1568Acyltransferase family protein. (350 aa)
SVI_4097Glycosyl transferase, group 2 family protein. (571 aa)
kdsB-23-deoxy-manno-octulosonate cytidylyltransferase; Activates KDO8N (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in the Shewanella genus. Belongs to the KdsB family. (245 aa)
SVI_1928Alcohol dehydrogenase, iron-containing. (369 aa)
SVI_1929Polysaccharide biosynthesis protein; Belongs to the DegT/DnrJ/EryC1 family. (394 aa)
lapAConserved hypothetical protein; Involved in the assembly of lipopolysaccharide (LPS). Belongs to the LapA family. (96 aa)
lapBConserved hypothetical protein; Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane; Belongs to the LapB family. (386 aa)
SVI_2311Membrane protein, putative. (547 aa)
lpxMLipid A biosynthesis acyltransferase, putative; Catalyzes the transfer of myristate from myristoyl-acyl carrier protein (ACP) to Kdo(2)-(lauroyl)-lipid IV(A) to form Kdo(2)- lipid A. (311 aa)
lpxKTetraacyldisaccharide 4'-kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA). (340 aa)
glmUUDP-N-acetylglucosamine pyrophosphorylase/glucosamine-1-phosphate N-acetyltransferase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. (454 aa)
lpxHUDP-2,3-diacylglucosamine hydrolase; Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. (244 aa)
kdsA2-dehydro-3-deoxyphosphooctonate aldolase; Belongs to the KdsA family. (282 aa)
SVI_3503Hypothetical protein. (182 aa)
Your Current Organism:
Shewanella violacea
NCBI taxonomy Id: 637905
Other names: S. violacea DSS12, Shewanella violacea DSS12, Shewanella violacea JCM 10179, Shewanella violacea str. DSS12, Shewanella violacea strain DSS12
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