(23 nodes) Exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5-phosphomonoesters network (Grosmannia clavigera)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	CMQ_7979	Caf1 family ribonuclease. (361 aa)
	CMQ_4845	RasGAP. (3016 aa)
	CMQ_4585	RNA exonuclease. (205 aa)
	CMQ_899	DNA repair protein pso2. (883 aa)
	USB1	U6 snRNA phosphodiesterase; Phosphodiesterase responsible for the U6 snRNA 3' end processing. Acts as an exoribonuclease (RNase) responsible for trimming the poly(U) tract of the last nucleotides in the pre-U6 snRNA molecule, leading to the formation of mature U6 snRNA; Belongs to the 2H phosphoesterase superfamily. USB1 family. (339 aa)
	CMQ_2030	Exosome complex exonuclease. (1631 aa)
	CMQ_5212	DNA lyase. (795 aa)
	PAN2	PAN2-PAN3 deadenylation complex catalytic subunit PAN2; Catalytic subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in mRNA turnover. PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein PAB1. PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex. Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent mRNA decaping and subsequent [...] (1223 aa)
	CMQ_7803	DNA polymerase. (1105 aa)
	CMQ_7873	Cell wall biogenesis protein phosphatase. (1428 aa)
	CMQ_5726	Ccr4-not core complex subunit. (434 aa)
	CMQ_6372	Endonuclease exonuclease phosphatase family protein. (314 aa)
	CMQ_4237	Uncharacterized protein. (570 aa)
	CMQ_7206	Transcriptional effector. (693 aa)
	CMQ_3625	Meiotic recombination protein mre11. (1249 aa)
	CMQ_3409	Deoxyribonuclease. (412 aa)
	CMQ_6035	Histidine triad nucleotide-binding protein. (311 aa)
	CMQ_8304	Exosome complex exonuclease exoribonuclease; Belongs to the RNR ribonuclease family. (1030 aa)
	CMQ_2735	Mitochondrial exoribonuclease. (1159 aa)
	CMQ_2696	5'-3' exoribonuclease 1; Multifunctional protein that exhibits several independent functions at different levels of the cellular processes. 5'-3' exonuclease component of the nonsense-mediated mRNA decay (NMD) which is a highly conserved mRNA degradation pathway, an RNA surveillance system whose role is to identify and rid cells of mRNA with premature termination codons and thus prevents accumulation of potentially harmful truncated proteins. (1463 aa)
	CMQ_5390	DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (2353 aa)
	CMQ_654	Exodeoxyribonuclease 1. (805 aa)
	CMQ_1119	3-5 exonuclease helicase. (525 aa)

Your Current Organism:

Grosmannia clavigera

NCBI taxonomy Id: 655863
Other names: G. clavigera kw1407, Grosmannia clavigera kw1407

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CMQ_1119	CMQ_2030	F0XEG4	F0XN94	3-5 exonuclease helicase.	Exosome complex exonuclease.	0.644
CMQ_1119	CMQ_3625	F0XEG4	F0X8Q5	3-5 exonuclease helicase.	Meiotic recombination protein mre11.	0.999
CMQ_1119	CMQ_5212	F0XEG4	F0XBB2	3-5 exonuclease helicase.	DNA lyase.	0.617
CMQ_1119	CMQ_5390	F0XEG4	F0XG10	3-5 exonuclease helicase.	DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family.	0.993
CMQ_1119	CMQ_6035	F0XEG4	F0XMD7	3-5 exonuclease helicase.	Histidine triad nucleotide-binding protein.	0.523
CMQ_1119	CMQ_654	F0XEG4	F0XEI8	3-5 exonuclease helicase.	Exodeoxyribonuclease 1.	0.999
CMQ_1119	CMQ_7803	F0XEG4	F0XRT7	3-5 exonuclease helicase.	DNA polymerase.	0.994
CMQ_1119	CMQ_899	F0XEG4	F0XDQ8	3-5 exonuclease helicase.	DNA repair protein pso2.	0.493
CMQ_2030	CMQ_1119	F0XN94	F0XEG4	Exosome complex exonuclease.	3-5 exonuclease helicase.	0.644
CMQ_2030	CMQ_2735	F0XN94	F0XHB6	Exosome complex exonuclease.	Mitochondrial exoribonuclease.	0.470
CMQ_2030	CMQ_3625	F0XN94	F0X8Q5	Exosome complex exonuclease.	Meiotic recombination protein mre11.	0.692
CMQ_2030	CMQ_4845	F0XN94	F0XTD1	Exosome complex exonuclease.	RasGAP.	0.542
CMQ_2030	CMQ_7873	F0XN94	F0XRU1	Exosome complex exonuclease.	Cell wall biogenesis protein phosphatase.	0.704
CMQ_2030	CMQ_8304	F0XN94	F0XKX1	Exosome complex exonuclease.	Exosome complex exonuclease exoribonuclease; Belongs to the RNR ribonuclease family.	0.802
CMQ_2030	CMQ_899	F0XN94	F0XDQ8	Exosome complex exonuclease.	DNA repair protein pso2.	0.855
CMQ_2696	CMQ_2735	F0XG72	F0XHB6	5'-3' exoribonuclease 1; Multifunctional protein that exhibits several independent functions at different levels of the cellular processes. 5'-3' exonuclease component of the nonsense-mediated mRNA decay (NMD) which is a highly conserved mRNA degradation pathway, an RNA surveillance system whose role is to identify and rid cells of mRNA with premature termination codons and thus prevents accumulation of potentially harmful truncated proteins.	Mitochondrial exoribonuclease.	0.793
CMQ_2696	CMQ_4845	F0XG72	F0XTD1	5'-3' exoribonuclease 1; Multifunctional protein that exhibits several independent functions at different levels of the cellular processes. 5'-3' exonuclease component of the nonsense-mediated mRNA decay (NMD) which is a highly conserved mRNA degradation pathway, an RNA surveillance system whose role is to identify and rid cells of mRNA with premature termination codons and thus prevents accumulation of potentially harmful truncated proteins.	RasGAP.	0.951
CMQ_2696	CMQ_5726	F0XG72	F0XSF7	5'-3' exoribonuclease 1; Multifunctional protein that exhibits several independent functions at different levels of the cellular processes. 5'-3' exonuclease component of the nonsense-mediated mRNA decay (NMD) which is a highly conserved mRNA degradation pathway, an RNA surveillance system whose role is to identify and rid cells of mRNA with premature termination codons and thus prevents accumulation of potentially harmful truncated proteins.	Ccr4-not core complex subunit.	0.439
CMQ_2696	CMQ_7206	F0XG72	F0XP06	5'-3' exoribonuclease 1; Multifunctional protein that exhibits several independent functions at different levels of the cellular processes. 5'-3' exonuclease component of the nonsense-mediated mRNA decay (NMD) which is a highly conserved mRNA degradation pathway, an RNA surveillance system whose role is to identify and rid cells of mRNA with premature termination codons and thus prevents accumulation of potentially harmful truncated proteins.	Transcriptional effector.	0.463
CMQ_2696	CMQ_7873	F0XG72	F0XRU1	5'-3' exoribonuclease 1; Multifunctional protein that exhibits several independent functions at different levels of the cellular processes. 5'-3' exonuclease component of the nonsense-mediated mRNA decay (NMD) which is a highly conserved mRNA degradation pathway, an RNA surveillance system whose role is to identify and rid cells of mRNA with premature termination codons and thus prevents accumulation of potentially harmful truncated proteins.	Cell wall biogenesis protein phosphatase.	0.832