(79 nodes) Actin cytoskeleton organization network (Grosmannia clavigera)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	CMQ_6171	Actin-related protein 2/3 complex subunit; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks; Belongs to the WD repeat ARPC1 family. (363 aa)
	CMQ_6408	Drf_GBD domain-containing protein. (856 aa)
	CMQ_8255	Rho GTPase rho. (201 aa)
	CMQ_8101	Serine/threonine-protein kinase. (667 aa)
	CMQ_5059	Actin associated protein. (693 aa)
	CMQ_5091	Myosin type 2 heavy; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2493 aa)
	CMQ_5024	Rpel repeat protein. (118 aa)
	CMQ_2429	GTPase activating protein. (1274 aa)
	CMQ_2161	Protein rho3. (208 aa)
	CMQ_2226	Class 2 aldolase adducin domain containing protein. (290 aa)
	CMQ_2360	Hr1-like Rho-binding repeat protein. (1667 aa)
	CMQ_5819	Rho GTPase activator. (1207 aa)
	CMQ_2999	Profilin; Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations. (133 aa)
	CMQ_2690	Ankyrin unc44. (177 aa)
	CMQ_3156	Rho-like GTPase cdc42. (194 aa)
	CMQ_2919	Cytoskeletal adaptor protein. (923 aa)
	CMQ_5455	F-actin-capping protein subunit alpha; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. (275 aa)
	CMQ_7507	Sh3 domain protein. (1067 aa)
	CMQ_383	WD-repeat protein pop3. (359 aa)
	CMQ_4766	Duf829 domain containing protein. (333 aa)
	CMQ_4397	PH domain containing protein. (469 aa)
	CMQ_4429	Actin-binding protein. (761 aa)
	CMQ_4774	Coronin; Belongs to the WD repeat coronin family. (603 aa)
	CMQ_4643	Class 2 aldolase adducin domain containing protein. (311 aa)
	CMQ_4341	Rho GTPase rho1. (196 aa)
	CMQ_4311	Cofilin; Belongs to the actin-binding proteins ADF family. (152 aa)
	CMQ_5764	Cell division control protein. (961 aa)
	CMQ_5745	Actin polymerization protein. (731 aa)
	CMQ_5759	Uncharacterized protein. (612 aa)
	CMQ_5637	Bar adaptor protein. (473 aa)
	CMQ_5768	Actin cortical patch. (627 aa)
	CMQ_5515	Actin-bundling protein. (655 aa)
	CMQ_7973	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family. (1680 aa)
	CMQ_7837	C6 zinc finger domain containing protein. (651 aa)
	CMQ_5474	Actin-related protein 2; ATP-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility. Seems to contact the pointed end of the daughter actin filament. (390 aa)
	CMQ_22	Actin. (375 aa)
	CMQ_64	Arp2/3 complex 34 kDa subunit; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (318 aa)
	CMQ_7664	Gelsolin domain containing protein. (1470 aa)
	CMQ_7069	Calcium-binding ef-hand protein. (346 aa)
	CMQ_7054	Uncharacterized protein. (794 aa)
	CMQ_931	Protein-tyrosine phosphatase. (674 aa)
	CMQ_1560	Class 2 aldolase adducin domain containing protein. (293 aa)
	CMQ_1161	Rho-like protein. (195 aa)
	CMQ_647	Actin-related protein 2/3 complex subunit 5; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development. (204 aa)
	CMQ_580	Cytokinesis protein bni1. (1728 aa)
	CMQ_1451	Golgi to endosome transport protein. (573 aa)
	CMQ_1359	Myosin 1 myo5; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1234 aa)
	CMQ_1176	Serine/threonine-protein kinase. (1042 aa)
	CMQ_1478	Eh domain protein. (518 aa)
	CMQ_5267	Indole-diterpene biosynthesis protein. (299 aa)
	CMQ_5220	Actin-related protein 2/3 complex subunit 4; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Seems to contact the mother actin filament; Belongs to the ARPC4 family. (169 aa)
	CMQ_5284	Uncharacterized protein. (457 aa)
	CMQ_5197	Cytoskeleton assembly control protein. (1035 aa)
	CMQ_3992	Actin lateral-binding protein. (161 aa)
	CMQ_4132	Uncharacterized protein. (329 aa)
	CMQ_4013	Lim domain containing protein. (1033 aa)
	CMQ_3424	Sh3 domain containing protein. (1259 aa)
	CMQ_3696	Rho-GDP dissociation inhibitor. (248 aa)
	CMQ_3602	Myosin regulatory light chain cdc4. (223 aa)
	CMQ_3794	MHD domain-containing protein. (949 aa)
	CMQ_6912	Arp2 3 complex subunit; Belongs to the actin family. (439 aa)
	CMQ_6971	Arp2 3 complex subunit. (239 aa)
	CMQ_6625	Actin-binding protein. (781 aa)
	CMQ_6652	Ras family GTP-binding protein rho1p. (537 aa)
	CMQ_6602	Bud-6-like, actin-interacting protein. (1388 aa)
	CMQ_6768	Tyrosine phosphatase family protein. (343 aa)
	CMQ_6540	Rho GTPase. (296 aa)
	CMQ_1428	Adenylyl cyclase-associated protein; Belongs to the CAP family. (566 aa)
	CMQ_7610	Pak-box/p21-Rho-binding protein. (750 aa)
	CMQ_7576	Class 2 aldolase adducin domain containing protein. (302 aa)
	CMQ_7109	Bar adaptor protein. (261 aa)
	CMQ_1907	DUF2013 domain-containing protein. (680 aa)
	CMQ_1912	C6 zinc finger domain containing protein. (711 aa)
	CMQ_6344	Class 2 aldolase adducin domain containing protein. (289 aa)
	CMQ_5961	Cytoskeleton assembly control protein. (1783 aa)
	CMQ_5956	Vacuolar dynamin-like GTPase; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (699 aa)
	CMQ_6297	Duf500 and sh3 domain containing protein. (420 aa)
	CMQ_6136	Vhs domain containing protein. (459 aa)
	CMQ_6159	Uncharacterized protein. (419 aa)

Your Current Organism:

Grosmannia clavigera

NCBI taxonomy Id: 655863
Other names: G. clavigera kw1407, Grosmannia clavigera kw1407

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CMQ_1161	CMQ_1560	F0XDE2	F0XE66	Rho-like protein.	Class 2 aldolase adducin domain containing protein.	0.475
CMQ_1161	CMQ_1907	F0XDE2	F0XNE9	Rho-like protein.	DUF2013 domain-containing protein.	0.588
CMQ_1161	CMQ_1912	F0XDE2	F0XN13	Rho-like protein.	C6 zinc finger domain containing protein.	0.527
CMQ_1161	CMQ_22	F0XDE2	F0XRF4	Rho-like protein.	Actin.	0.637
CMQ_1161	CMQ_2226	F0XDE2	F0XJ68	Rho-like protein.	Class 2 aldolase adducin domain containing protein.	0.475
CMQ_1161	CMQ_2429	F0XDE2	F0XJG7	Rho-like protein.	GTPase activating protein.	0.479
CMQ_1161	CMQ_2999	F0XDE2	F0XHV8	Rho-like protein.	Profilin; Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations.	0.684
CMQ_1161	CMQ_3156	F0XDE2	F0XH02	Rho-like protein.	Rho-like GTPase cdc42.	0.728
CMQ_1161	CMQ_3602	F0XDE2	F0X857	Rho-like protein.	Myosin regulatory light chain cdc4.	0.684
CMQ_1161	CMQ_3696	F0XDE2	F0X8I1	Rho-like protein.	Rho-GDP dissociation inhibitor.	0.871
CMQ_1161	CMQ_383	F0XDE2	F0XFP1	Rho-like protein.	WD-repeat protein pop3.	0.596
CMQ_1161	CMQ_3992	F0XDE2	F0XA92	Rho-like protein.	Actin lateral-binding protein.	0.673
CMQ_1161	CMQ_4013	F0XDE2	F0X9B6	Rho-like protein.	Lim domain containing protein.	0.756
CMQ_1161	CMQ_4341	F0XDE2	F0XTM5	Rho-like protein.	Rho GTPase rho1.	0.844
CMQ_1161	CMQ_4397	F0XDE2	F0XUR1	Rho-like protein.	PH domain containing protein.	0.596
CMQ_1161	CMQ_4429	F0XDE2	F0XUF4	Rho-like protein.	Actin-binding protein.	0.629
CMQ_1161	CMQ_4643	F0XDE2	F0XU03	Rho-like protein.	Class 2 aldolase adducin domain containing protein.	0.475
CMQ_1161	CMQ_5059	F0XDE2	F0XK60	Rho-like protein.	Actin associated protein.	0.712
CMQ_1161	CMQ_5091	F0XDE2	F0XK37	Rho-like protein.	Myosin type 2 heavy; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.	0.670
CMQ_1161	CMQ_5197	F0XDE2	F0XBC0	Rho-like protein.	Cytoskeleton assembly control protein.	0.425