STRINGSTRING
arnB arnB arnC arnC arnA arnA arnD arnD ARD38259.1 ARD38259.1 ARD38305.1 ARD38305.1 ARD38306.1 ARD38306.1 ARD38307.1 ARD38307.1 nagZ nagZ ARD38503.1 ARD38503.1 ARD40864.1 ARD40864.1 ARD38662.1 ARD38662.1 ARD39025.1 ARD39025.1 ARD39026.1 ARD39026.1 galK galK B6E78_06395 B6E78_06395 B6E78_06430 B6E78_06430 ARD39075.1 ARD39075.1 nagB nagB ARD39077.1 ARD39077.1 glgC glgC glgC-2 glgC-2 glmU glmU glmS glmS wecB wecB wecC wecC murB murB pgi pgi glmM glmM murA murA ARD40286.1 ARD40286.1 nanE nanE murQ murQ B6E78_15455 B6E78_15455 ARD40765.1 ARD40765.1 glk glk B6E78_16825 B6E78_16825 ARD40816.1 ARD40816.1 ARD40817.1 ARD40817.1 ARD40818.1 ARD40818.1 ARD40968.1 ARD40968.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
arnBUDP-4-amino-4-deoxy-L-arabinose--oxoglutarate aminotransferase; Catalyzes the conversion of UDP-4-keto-arabinose (UDP-Ara4O) to UDP-4-amino-4-deoxy-L-arabinose (UDP-L-Ara4N). The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides; Belongs to the DegT/DnrJ/EryC1 family. ArnB subfamily. (381 aa)
arnCUndecaprenyl-phosphate 4-deoxy-4-formamido-L-arabinose transferase; Catalyzes the transfer of 4-deoxy-4-formamido-L-arabinose from UDP to undecaprenyl phosphate. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides. (325 aa)
arnABifunctional UDP-glucuronic acid oxidase/UDP-4-amino-4-deoxy-L-arabinose formyltransferase; Bifunctional enzyme that catalyzes the oxidative decarboxylation of UDP-glucuronic acid (UDP-GlcUA) to UDP-4-keto- arabinose (UDP-Ara4O) and the addition of a formyl group to UDP-4- amino-4-deoxy-L-arabinose (UDP-L-Ara4N) to form UDP-L-4-formamido- arabinose (UDP-L-Ara4FN). The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides; In the N-terminal section; belongs to the Fmt family. UDP- L-Ara4N formyltransferase subfamily. (659 aa)
arnD4-deoxy-4-formamido-L-arabinose- phosphoundecaprenol deformylase; Catalyzes the deformylation of 4-deoxy-4-formamido-L- arabinose-phosphoundecaprenol to 4-amino-4-deoxy-L-arabinose- phosphoundecaprenol. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides; Belongs to the polysaccharide deacetylase family. ArnD deformylase subfamily. (299 aa)
ARD38259.1UTP--glucose-1-phosphate uridylyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (303 aa)
ARD38305.1PTS mannose transporter subunit IID; Hosphoenolpyruvate-dependent sugar phosphotransferase system catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IID with IIC forms the translocation channel; Derived by automated computational analysis using gene prediction method: Protein Homology. (287 aa)
ARD38306.1PTS mannose/fructose/sorbose transporter subunit IIC; Catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; the IIC domain forms the PTS system translocation channel and contains the specific substrate-binding site; Derived by automated computational analysis using gene prediction method: Protein Homology. (266 aa)
ARD38307.1PTS mannose transporter subunit EIIAB; Derived by automated computational analysis using gene prediction method: Protein Homology. (321 aa)
nagZbeta-N-acetylhexosaminidase; Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide- linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N- acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides. Belongs to the glycosyl hydrolase 3 family. NagZ subfamily. (340 aa)
ARD38503.1Mannose-6-phosphate isomerase; Catalyzes the formation of of fructose 6-phosphate from mannose 6-phosphate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the mannose-6-phosphate isomerase type 1 family. (392 aa)
ARD40864.1N-acetylglucosamine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (318 aa)
ARD38662.1PTS glucose transporter subunit IIBC; Derived by automated computational analysis using gene prediction method: Protein Homology. (477 aa)
ARD39025.1UDP-glucose 4-epimerase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the NAD(P)-dependent epimerase/dehydratase family. (338 aa)
ARD39026.1Galactose-1-phosphate uridylyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the galactose-1-phosphate uridylyltransferase type 1 family. (347 aa)
galKGalactokinase; Catalyzes the transfer of the gamma-phosphate of ATP to D- galactose to form alpha-D-galactose-1-phosphate (Gal-1-P). Belongs to the GHMP kinase family. GalK subfamily. (385 aa)
B6E78_06395IS200/IS605 family transposase; Internal stop; Derived by automated computational analysis using gene prediction method: Protein Homology. (546 aa)
B6E78_06430Hypothetical protein; Frameshifted; internal stop; Derived by automated computational analysis using gene prediction method: Protein Homology. (888 aa)
ARD39075.1PTS N-acetyl glucosamine transporter subunit IIABC; Phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel; Derived by automated computational analysis using gene prediction method: Protein Homology. (671 aa)
nagBGlucosamine-6-phosphate deaminase; Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion. (266 aa)
ARD39077.1N-acetylglucosamine-6-phosphate deacetylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (384 aa)
glgCGlucose-1-phosphate adenylyltransferase; Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc; Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family. (438 aa)
glgC-2Glucose-1-phosphate adenylyltransferase; Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc; Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family. (426 aa)
glmUUDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. In the C-terminal section; belongs to the trans [...] (456 aa)
glmSGlutamine--fructose-6-phosphate aminotransferase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. (609 aa)
wecBUDP-N-acetylglucosamine 2-epimerase (non-hydrolyzing); Catalyzes the reversible epimerization at C-2 of UDP-N- acetylglucosamine (UDP-GlcNAc) and thereby provides bacteria with UDP- N-acetylmannosamine (UDP-ManNAc), the activated donor of ManNAc residues. (376 aa)
wecCUDP-N-acetyl-D-mannosamine dehydrogenase; Catalyzes the four-electron oxidation of UDP-N-acetyl-D- mannosamine (UDP-ManNAc), reducing NAD(+) and releasing UDP-N- acetylmannosaminuronic acid (UDP-ManNAcA); Belongs to the UDP-glucose/GDP-mannose dehydrogenase family. WecC subfamily. (420 aa)
murBUDP-N-acetylenolpyruvoylglucosamine reductase; Cell wall formation. (345 aa)
pgiHypothetical protein; Frameshifted; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the GPI family. (549 aa)
glmMPhosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family. (445 aa)
murAUDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. (418 aa)
ARD40286.1N-acetylmannosamine kinase; Catalyzes the phosphorylation of the N-acetylmannosamine (ManNAc) liberated from N-acetyl-neuraminic acid by the nanA protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (291 aa)
nanEN-acetylmannosamine-6-phosphate 2-epimerase; Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N- acetylglucosamine-6-phosphate (GlcNAc-6-P). (235 aa)
murQN-acetylmuramic acid 6-phosphate etherase; Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D- lactate. Together with AnmK, is also required for the utilization of anhydro-N-acetylmuramic acid (anhMurNAc) either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the GCKR-like family. MurNAc-6-P etherase subfamily. (300 aa)
B6E78_15455DUF1275 family protein; Frameshifted; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the DapA family. (296 aa)
ARD40765.1PTS glucose transporter subunit IIA; Derived by automated computational analysis using gene prediction method: Protein Homology. (169 aa)
glkGlucokinase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the bacterial glucokinase family. (321 aa)
B6E78_16825UDP-N-acetylglucosamine 4-epimerase; Frameshifted; Derived by automated computational analysis using gene prediction method: Protein Homology. (300 aa)
ARD40816.1UDP-glucose 4-epimerase GalE; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the NAD(P)-dependent epimerase/dehydratase family. (338 aa)
ARD40817.1UDP-glucose 6-dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (388 aa)
ARD40818.1Protein CapI; Derived by automated computational analysis using gene prediction method: Protein Homology. (335 aa)
ARD40968.1N-acetylneuraminate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (346 aa)
Your Current Organism:
Edwardsiella ictaluri
NCBI taxonomy Id: 67780
Other names: ATCC 33202, CCUG 18764, CIP 81.96, DSM 13697, E. ictaluri, JCM 16934, NCTC 12122, SECFDL GA 77-52
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