STRINGSTRING
moaA moaA EGW21600.1 EGW21600.1 thiL thiL mobA mobA EGW22782.1 EGW22782.1 thiG thiG moaC moaC EGW23538.1 EGW23538.1 EGW23539.1 EGW23539.1 thiC thiC EGW23851.1 EGW23851.1 EGW23852.1 EGW23852.1 EGW23853.1 EGW23853.1 EGW23854.1 EGW23854.1 EGW20013.1 EGW20013.1 EGW20014.1 EGW20014.1 EGW20101.1 EGW20101.1 EGW20177.1 EGW20177.1 EGW20179.1 EGW20179.1 EGW20180.1 EGW20180.1 EGW20181.1 EGW20181.1 modC modC EGW20183.1 EGW20183.1 EGW20184.1 EGW20184.1 rsgA rsgA thiE thiE EGW21147.1 EGW21147.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
moaAMolybdenum cofactor biosynthesis protein A; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate. (334 aa)
EGW21600.1KEGG: sna:Snas_2007 hypothetical protein. (292 aa)
thiLThiamine-monophosphate kinase; Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1; Belongs to the thiamine-monophosphate kinase family. (311 aa)
mobAMolybdopterin-guanine dinucleotide biosynthesis protein A; Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor; Belongs to the MobA family. (203 aa)
EGW22782.1Molybdenum cofactor biosynthesis protein B; May be involved in the biosynthesis of molybdopterin. Belongs to the MoaB/Mog family. (173 aa)
thiGThiazole synthase; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S. (325 aa)
moaCMolybdenum cofactor biosynthesis protein C; Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP); Belongs to the MoaC family. (160 aa)
EGW23538.1PFAM: ThiamineS; KEGG: tgr:Tgr7_2951 molybdopterin converting factor, subunit 1. (77 aa)
EGW23539.1PFAM: Molybdopterin biosynthesis MoaE; KEGG: tgr:Tgr7_2952 molybdopterin biosynthesis MoaE protein. (148 aa)
thiCPhosphomethylpyrimidine synthase; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. (626 aa)
EGW23851.1KEGG: har:HEAR2205 hypothetical protein. (166 aa)
EGW23852.1PFAM: UBA/THIF-type NAD/FAD binding fold; KEGG: vei:Veis_4665 UBA/ThiF-type NAD/FAD binding protein. (585 aa)
EGW23853.1KEGG: par:Psyc_1373 hypothetical protein. (396 aa)
EGW23854.1Transposase; Manually curated; KEGG: amr:AM1_2664 hypothetical protein. (356 aa)
EGW20013.1Molybdenum cofactor synthesis domain protein; Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. Belongs to the MoeA family. (414 aa)
EGW20014.1KEGG: mca:MCA2450 molybdopterin-guanine dinucleotide biosynthesis protein MobB; TIGRFAM: Molybdopterin-guanine dinucleotide biosynthesis MobB region; PFAM: Molybdopterin-guanine dinucleotide biosynthesis MobB region. (175 aa)
EGW20101.1PFAM: UBA/THIF-type NAD/FAD binding fold; MoeZ/MoeB; KEGG: tgr:Tgr7_0519 UBA/ThiF-type NAD/FAD binding fold protein. (248 aa)
EGW20177.1Transcriptional regulator, ModE family; KEGG: bpt:Bpet3267 molybdenum transporter; TIGRFAM: Molybdenum-pterin binding; PFAM: HTH transcriptional regulator, LysR; Transport-associated OB, type 1. (272 aa)
EGW20179.1PFAM: Protein of unknown function DUF81; KEGG: rpa:RPA3560 hypothetical protein. (261 aa)
EGW20180.1KEGG: har:HEAR3439 molybdate-binding periplasmic protein precursor; TIGRFAM: Molybdenum ABC transporter, periplasmic binding protein; PFAM: Bacterial extracellular solute-binding, family 1. (256 aa)
EGW20181.1Molybdate ABC transporter, inner membrane subunit; Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane; Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily. (228 aa)
modCMolybdate ABC transporter, ATPase subunit; Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Molybdate importer (TC 3.A.1.8) family. (375 aa)
EGW20183.1Molybdenum-pterin binding protein; KEGG: mca:MCA1381 molybdenum transport protein ModG, putative; TIGRFAM: Molybdenum-pterin binding; PFAM: Transport-associated OB, type 1. (142 aa)
EGW20184.1SMART: ATPase, AAA+ type, core; TIGRFAM: Molybdate ABC transporter, ATP-binding protein; KEGG: mca:MCA2836 molybdenum ABC transporter, ATP-binding protein, putative; PFAM: ABC transporter-like; Transport-associated OB, type 1; Belongs to the ABC transporter superfamily. (389 aa)
rsgARibosome biogenesis GTPase RsgA; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit; Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily. (295 aa)
thiEThiamine-phosphate pyrophosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family. (206 aa)
EGW21147.1KEGG: tgr:Tgr7_2419 phosphomethylpyrimidine kinase; PFAM: Phosphomethylpyrimidine kinase type-1. (262 aa)
Your Current Organism:
Methylobacter tundripaludum
NCBI taxonomy Id: 697282
Other names: M. tundripaludum SV96, Methylobacter sp. SV96, Methylobacter tundripaludum DSM 17260, Methylobacter tundripaludum SV96, Methylobacter tundripaludum str. SV96, Methylobacter tundripaludum strain SV96
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