| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| bipA | der | HI_0864 | HI_0136 | GTP-binding protein; A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily. | GTP-binding protein; GTPase that plays an essential role in the late steps of ribosome biogenesis; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family. | 0.680 |
| bipA | rimP | HI_0864 | HI_1282 | GTP-binding protein; A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily. | Conserved hypothetical protein; Required for maturation of 30S ribosomal subunits. Belongs to the RimP family. | 0.493 |
| deaD | rplT | HI_0231 | HI_1320 | ATP-dependent RNA helicase (deaD); DEAD-box RNA helicase involved in various cellular processes at low temperature, including ribosome biogenesis, mRNA degradation and translation initiation. | Ribosomal protein L20 (rpL20); Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity). | 0.417 |
| deaD | rplV | HI_0231 | HI_0782 | ATP-dependent RNA helicase (deaD); DEAD-box RNA helicase involved in various cellular processes at low temperature, including ribosome biogenesis, mRNA degradation and translation initiation. | Ribosomal protein L22 (rpL22); This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity). | 0.633 |
| deaD | rplW | HI_0231 | HI_0779 | ATP-dependent RNA helicase (deaD); DEAD-box RNA helicase involved in various cellular processes at low temperature, including ribosome biogenesis, mRNA degradation and translation initiation. | Ribosomal protein L23 (rpL23); One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome; Belongs to the universal ribosomal protein uL23 family. | 0.607 |
| deaD | rpsG | HI_0231 | HI_0580 | ATP-dependent RNA helicase (deaD); DEAD-box RNA helicase involved in various cellular processes at low temperature, including ribosome biogenesis, mRNA degradation and translation initiation. | Ribosomal protein S7 (rpS7); One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA; Belongs to the universal ribosomal protein uS7 family. | 0.486 |
| deaD | rpsK | HI_0231 | HI_0800 | ATP-dependent RNA helicase (deaD); DEAD-box RNA helicase involved in various cellular processes at low temperature, including ribosome biogenesis, mRNA degradation and translation initiation. | Ribosomal protein S11 (rpS11); Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine- Dalgarno cleft in the 70S ribosome; Belongs to the universal ribosomal protein uS11 family. | 0.701 |
| deaD | rpsS | HI_0231 | HI_0781 | ATP-dependent RNA helicase (deaD); DEAD-box RNA helicase involved in various cellular processes at low temperature, including ribosome biogenesis, mRNA degradation and translation initiation. | Ribosomal protein S19 (rpS19); Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA. | 0.419 |
| deaD | rsfS | HI_0231 | HI_0034 | ATP-dependent RNA helicase (deaD); DEAD-box RNA helicase involved in various cellular processes at low temperature, including ribosome biogenesis, mRNA degradation and translation initiation. | Conserved hypothetical protein; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation. | 0.655 |
| der | bipA | HI_0136 | HI_0864 | GTP-binding protein; GTPase that plays an essential role in the late steps of ribosome biogenesis; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family. | GTP-binding protein; A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily. | 0.680 |
| der | rplT | HI_0136 | HI_1320 | GTP-binding protein; GTPase that plays an essential role in the late steps of ribosome biogenesis; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family. | Ribosomal protein L20 (rpL20); Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity). | 0.428 |
| era | rimP | HI_0013 | HI_1282 | GTP-binding protein (era); An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism. | Conserved hypothetical protein; Required for maturation of 30S ribosomal subunits. Belongs to the RimP family. | 0.467 |
| era | rpsG | HI_0013 | HI_0580 | GTP-binding protein (era); An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism. | Ribosomal protein S7 (rpS7); One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA; Belongs to the universal ribosomal protein uS7 family. | 0.999 |
| era | rpsK | HI_0013 | HI_0800 | GTP-binding protein (era); An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism. | Ribosomal protein S11 (rpS11); Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine- Dalgarno cleft in the 70S ribosome; Belongs to the universal ribosomal protein uS11 family. | 0.999 |
| rimP | bipA | HI_1282 | HI_0864 | Conserved hypothetical protein; Required for maturation of 30S ribosomal subunits. Belongs to the RimP family. | GTP-binding protein; A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily. | 0.493 |
| rimP | era | HI_1282 | HI_0013 | Conserved hypothetical protein; Required for maturation of 30S ribosomal subunits. Belongs to the RimP family. | GTP-binding protein (era); An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism. | 0.467 |
| rimP | rpsG | HI_1282 | HI_0580 | Conserved hypothetical protein; Required for maturation of 30S ribosomal subunits. Belongs to the RimP family. | Ribosomal protein S7 (rpS7); One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA; Belongs to the universal ribosomal protein uS7 family. | 0.746 |
| rimP | rpsK | HI_1282 | HI_0800 | Conserved hypothetical protein; Required for maturation of 30S ribosomal subunits. Belongs to the RimP family. | Ribosomal protein S11 (rpS11); Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine- Dalgarno cleft in the 70S ribosome; Belongs to the universal ribosomal protein uS11 family. | 0.644 |
| rimP | rpsS | HI_1282 | HI_0781 | Conserved hypothetical protein; Required for maturation of 30S ribosomal subunits. Belongs to the RimP family. | Ribosomal protein S19 (rpS19); Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA. | 0.654 |
| rplT | deaD | HI_1320 | HI_0231 | Ribosomal protein L20 (rpL20); Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity). | ATP-dependent RNA helicase (deaD); DEAD-box RNA helicase involved in various cellular processes at low temperature, including ribosome biogenesis, mRNA degradation and translation initiation. | 0.417 |