(5 nodes) Attenuation phase network (Anopheles gambiae)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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second shell of interactors

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proteins of unknown 3D structure

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experimentally determined

Predicted Interactions

gene neighborhood

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textmining

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protein homology

Your Input:
	Q5TVJ4_ANOGA	Peptidylprolyl isomerase. (461 aa)
	Q7PF55_ANOGA	Molecular chaperone HtpG. (369 aa)
	Q7PSZ8_ANOGA	Molecular chaperone HtpG. (393 aa)
	Hsp83	Heat shock protein 83; Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co- chaperones that modulate its substrate recognition, ATPase cycle and chaperone function. Required for piRNA biogenesis by facilitating loading of piRNAs into PIW [...] (720 aa)
	Q7QHE6_ANOGA	Cytosolic prostaglandin-E synthase. (170 aa)

Your Current Organism:

Anopheles gambiae

NCBI taxonomy Id: 7165
Other names: A. gambiae, African malaria mosquito, Anopheles gambiae S, Anopheles gambiae sensu stricto

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Hsp83	Q5TVJ4_ANOGA	Q7PT10	Q5TVJ4	Heat shock protein 83; Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co- chaperones that modulate its substrate recognition, ATPase cycle and chaperone function. Required for piRNA biogenesis by facilitating loading of piRNAs into PIW [...]	Peptidylprolyl isomerase.	0.821
Hsp83	Q7PF55_ANOGA	Q7PT10	Q7PF55	Heat shock protein 83; Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co- chaperones that modulate its substrate recognition, ATPase cycle and chaperone function. Required for piRNA biogenesis by facilitating loading of piRNAs into PIW [...]	Molecular chaperone HtpG.	0.901
Hsp83	Q7PSZ8_ANOGA	Q7PT10	Q7PSZ8	Heat shock protein 83; Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co- chaperones that modulate its substrate recognition, ATPase cycle and chaperone function. Required for piRNA biogenesis by facilitating loading of piRNAs into PIW [...]	Molecular chaperone HtpG.	0.901
Hsp83	Q7QHE6_ANOGA	Q7PT10	Q7QHE6	Heat shock protein 83; Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co- chaperones that modulate its substrate recognition, ATPase cycle and chaperone function. Required for piRNA biogenesis by facilitating loading of piRNAs into PIW [...]	Cytosolic prostaglandin-E synthase.	0.912
Q5TVJ4_ANOGA	Hsp83	Q5TVJ4	Q7PT10	Peptidylprolyl isomerase.	Heat shock protein 83; Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co- chaperones that modulate its substrate recognition, ATPase cycle and chaperone function. Required for piRNA biogenesis by facilitating loading of piRNAs into PIW [...]	0.821
Q5TVJ4_ANOGA	Q7PF55_ANOGA	Q5TVJ4	Q7PF55	Peptidylprolyl isomerase.	Molecular chaperone HtpG.	0.821
Q5TVJ4_ANOGA	Q7PSZ8_ANOGA	Q5TVJ4	Q7PSZ8	Peptidylprolyl isomerase.	Molecular chaperone HtpG.	0.821
Q5TVJ4_ANOGA	Q7QHE6_ANOGA	Q5TVJ4	Q7QHE6	Peptidylprolyl isomerase.	Cytosolic prostaglandin-E synthase.	0.959
Q7PF55_ANOGA	Hsp83	Q7PF55	Q7PT10	Molecular chaperone HtpG.	Heat shock protein 83; Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co- chaperones that modulate its substrate recognition, ATPase cycle and chaperone function. Required for piRNA biogenesis by facilitating loading of piRNAs into PIW [...]	0.901
Q7PF55_ANOGA	Q5TVJ4_ANOGA	Q7PF55	Q5TVJ4	Molecular chaperone HtpG.	Peptidylprolyl isomerase.	0.821
Q7PF55_ANOGA	Q7PSZ8_ANOGA	Q7PF55	Q7PSZ8	Molecular chaperone HtpG.	Molecular chaperone HtpG.	0.900
Q7PF55_ANOGA	Q7QHE6_ANOGA	Q7PF55	Q7QHE6	Molecular chaperone HtpG.	Cytosolic prostaglandin-E synthase.	0.912
Q7PSZ8_ANOGA	Hsp83	Q7PSZ8	Q7PT10	Molecular chaperone HtpG.	Heat shock protein 83; Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co- chaperones that modulate its substrate recognition, ATPase cycle and chaperone function. Required for piRNA biogenesis by facilitating loading of piRNAs into PIW [...]	0.901
Q7PSZ8_ANOGA	Q5TVJ4_ANOGA	Q7PSZ8	Q5TVJ4	Molecular chaperone HtpG.	Peptidylprolyl isomerase.	0.821
Q7PSZ8_ANOGA	Q7PF55_ANOGA	Q7PSZ8	Q7PF55	Molecular chaperone HtpG.	Molecular chaperone HtpG.	0.900
Q7PSZ8_ANOGA	Q7QHE6_ANOGA	Q7PSZ8	Q7QHE6	Molecular chaperone HtpG.	Cytosolic prostaglandin-E synthase.	0.912
Q7QHE6_ANOGA	Hsp83	Q7QHE6	Q7PT10	Cytosolic prostaglandin-E synthase.	Heat shock protein 83; Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co- chaperones that modulate its substrate recognition, ATPase cycle and chaperone function. Required for piRNA biogenesis by facilitating loading of piRNAs into PIW [...]	0.912
Q7QHE6_ANOGA	Q5TVJ4_ANOGA	Q7QHE6	Q5TVJ4	Cytosolic prostaglandin-E synthase.	Peptidylprolyl isomerase.	0.959
Q7QHE6_ANOGA	Q7PF55_ANOGA	Q7QHE6	Q7PF55	Cytosolic prostaglandin-E synthase.	Molecular chaperone HtpG.	0.912
Q7QHE6_ANOGA	Q7PSZ8_ANOGA	Q7QHE6	Q7PSZ8	Cytosolic prostaglandin-E synthase.	Molecular chaperone HtpG.	0.912