(27 nodes) Ephrin receptor binding network (Bos mutus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ENSBMUP00000005884	annotation not available (97 aa)
	ANKS1A	Ankyrin repeat and SAM domain-containing protein 1A. (1011 aa)
	SHC1	SHC-transforming protein 1. (501 aa)
	CBL	E3 ubiquitin-protein ligase CBL. (906 aa)
	AQP1	Aquaporin-1; Belongs to the MIP/aquaporin (TC 1.A.8) family. (271 aa)
	CRK	Adapter molecule crk. (304 aa)
	GRB2	Growth factor receptor-bound protein 2. (217 aa)
	PIK3CG	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma isoform; Belongs to the PI3/PI4-kinase family. (1104 aa)
	EFNB2	Ephrin-B2; Belongs to the ephrin family. (334 aa)
	ABL1	Tyrosine-protein kinase. (1151 aa)
	EFNA1	Ephrin-A1; Belongs to the ephrin family. (317 aa)
	EFNA3	Ephrin-A3; Belongs to the ephrin family. (238 aa)
	EFNA4	Ephrin-A4; Belongs to the ephrin family. (326 aa)
	EFNB3	Ephrin-B3; Belongs to the ephrin family. (340 aa)
	ANKS1B	Ankyrin repeat and sterile alpha motif domain containing 1B. (1165 aa)
	CHN1	N-chimaerin. (459 aa)
	EFNA2	Ephrin-A2; Belongs to the ephrin family. (203 aa)
	NCK1	Cytoplasmic protein NCK1. (377 aa)
	LOC102274505	Ankyrin repeat and SAM domain-containing protein 1A-like. (173 aa)
	SRC	Tyrosine-protein kinase. (559 aa)
	PTPN1	Tyrosine-protein phosphatase non-receptor type 1. (429 aa)
	LYN	Tyrosine-protein kinase. (512 aa)
	SIPA1L1	Signal-induced proliferation-associated 1-like protein 1. (1805 aa)
	FYN	Tyrosine-protein kinase. (537 aa)
	EFNB1	Ephrin-B1; Belongs to the ephrin family. (346 aa)
	EFNA5	Ephrin-A5; Belongs to the ephrin family. (188 aa)
	ENSBMUP00000017083	annotation not available (99 aa)

Your Current Organism:

Bos mutus

NCBI taxonomy Id: 72004
Other names: B. mutus, Bos grunniens mutus, Poephagus mutus, wild yak

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ABL1	CBL	ENSBMUP00000007604	ENSBMUP00000013771	Tyrosine-protein kinase.	E3 ubiquitin-protein ligase CBL.	0.568
ABL1	CRK	ENSBMUP00000007604	ENSBMUP00000013016	Tyrosine-protein kinase.	Adapter molecule crk.	0.764
ABL1	GRB2	ENSBMUP00000007604	ENSBMUP00000011430	Tyrosine-protein kinase.	Growth factor receptor-bound protein 2.	0.634
ABL1	NCK1	ENSBMUP00000007604	ENSBMUP00000004617	Tyrosine-protein kinase.	Cytoplasmic protein NCK1.	0.527
ANKS1A	LOC102274505	ENSBMUP00000015269	ENSBMUP00000001888	Ankyrin repeat and SAM domain-containing protein 1A.	Ankyrin repeat and SAM domain-containing protein 1A-like.	0.899
ANKS1B	ENSBMUP00000005884	ENSBMUP00000032349	ENSBMUP00000005884	Ankyrin repeat and sterile alpha motif domain containing 1B.	annotation not available	0.697
CBL	ABL1	ENSBMUP00000013771	ENSBMUP00000007604	E3 ubiquitin-protein ligase CBL.	Tyrosine-protein kinase.	0.568
CBL	CRK	ENSBMUP00000013771	ENSBMUP00000013016	E3 ubiquitin-protein ligase CBL.	Adapter molecule crk.	0.975
CBL	FYN	ENSBMUP00000013771	ENSBMUP00000022504	E3 ubiquitin-protein ligase CBL.	Tyrosine-protein kinase.	0.864
CBL	GRB2	ENSBMUP00000013771	ENSBMUP00000011430	E3 ubiquitin-protein ligase CBL.	Growth factor receptor-bound protein 2.	0.998
CBL	LYN	ENSBMUP00000013771	ENSBMUP00000015275	E3 ubiquitin-protein ligase CBL.	Tyrosine-protein kinase.	0.923
CBL	NCK1	ENSBMUP00000013771	ENSBMUP00000004617	E3 ubiquitin-protein ligase CBL.	Cytoplasmic protein NCK1.	0.758
CBL	PIK3CG	ENSBMUP00000013771	ENSBMUP00000010412	E3 ubiquitin-protein ligase CBL.	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma isoform; Belongs to the PI3/PI4-kinase family.	0.427
CBL	SHC1	ENSBMUP00000013771	ENSBMUP00000014795	E3 ubiquitin-protein ligase CBL.	SHC-transforming protein 1.	0.649
CBL	SRC	ENSBMUP00000013771	ENSBMUP00000000746	E3 ubiquitin-protein ligase CBL.	Tyrosine-protein kinase.	0.892
CRK	ABL1	ENSBMUP00000013016	ENSBMUP00000007604	Adapter molecule crk.	Tyrosine-protein kinase.	0.764
CRK	CBL	ENSBMUP00000013016	ENSBMUP00000013771	Adapter molecule crk.	E3 ubiquitin-protein ligase CBL.	0.975
CRK	FYN	ENSBMUP00000013016	ENSBMUP00000022504	Adapter molecule crk.	Tyrosine-protein kinase.	0.628
CRK	GRB2	ENSBMUP00000013016	ENSBMUP00000011430	Adapter molecule crk.	Growth factor receptor-bound protein 2.	0.852
CRK	LYN	ENSBMUP00000013016	ENSBMUP00000015275	Adapter molecule crk.	Tyrosine-protein kinase.	0.456