STRINGSTRING
atms atms CG9899 CG9899 Ctr9 Ctr9 CG12674 CG12674 Atu Atu CG3909 CG3909 CG10887 CG10887 tplus3a tplus3a tplus3b tplus3b CG6220 CG6220 hyx hyx Rtf1 Rtf1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
atmsAntimeros, isoform A; Antimeros (atms) encodes a component of the PAF1 complex (together with the products of Atu, hyx, Rtf1 and Ctr9). The PAF1 complex physically interacts with components of the basal transcription machinery and sequence-specific transcription factors to control histone modifications and pause release. (538 aa)
CG9899TPR_REGION domain-containing protein; RNA polymerase II complex binding; SH2 domain binding. It is involved in the biological process described with: positive regulation of transcription by RNA polymerase II; regulation of transcription, DNA-templated; regulation of histone H3-K4 methylation. (922 aa)
Ctr9Ctr9, isoform A; Ctr9 (Ctr9) encodes a highly conserved member of the polymerase-associated factor 1 complex, which controls a number of transcriptional and epigenetic processes. It is involved in the proliferation and terminal differentiation of the central nervous system. (1150 aa)
CG12674IP09436p; Chromatin binding; RNA polymerase II complex binding. It is involved in the biological process described with: transcription elongation from RNA polymerase II promoter; histone modification. (314 aa)
AtuAnother transcription unit protein; RNA polymerase II C-terminal domain phosphoserine binding. It is involved in the biological process described with: positive regulation of transcription elongation from RNA polymerase II promoter; histone modification; regulation of hemocyte proliferation. (725 aa)
CG3909WD_REPEATS_REGION domain-containing protein. (331 aa)
CG10887MIP29558p; RNA polymerase II C-terminal domain phosphoserine binding. It is involved in the biological process described with: positive regulation of transcription elongation from RNA polymerase II promoter; histone modification. (676 aa)
tplus3aFI11009p; RNA polymerase II C-terminal domain phosphoserine binding; DNA binding. (441 aa)
tplus3bPlus3 domain-containing protein; DNA binding; RNA polymerase II C-terminal domain phosphoserine binding. (439 aa)
CG6220FI06213p; RNA polymerase II complex binding. It is involved in the biological process described with: positive regulation of transcription elongation from RNA polymerase II promoter; recruitment of 3'-end processing factors to RNA polymerase II holoenzyme complex; histone modification; negative regulation of transcription by RNA polymerase II. (359 aa)
hyxHyrax, isoform A; Hyrax (hyx) encodes a protein recruited by signaling pathway specific transcriptional regulators such as the products of arm and ci and is important for the output of Wingless and Hedgehog pathways. (538 aa)
Rtf1RNA polymerase-associated protein Rtf1; Plays a role in transcription-coupled histone modification. Required for methylation of 'Lys-4' of histone H3. Plays a role in regulation of transcription. Required for maximal induction of heat- shock genes. Plays a role in Notch signaling in the wing margins. (775 aa)
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
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