STRINGSTRING
CG5589 CG5589 mRpL20 mRpL20 CG4901 CG4901 RpS13 RpS13 mRpS18A mRpS18A CG7488 CG7488 mRpL11 mRpL11 RpS5b RpS5b Non3 Non3 ppan ppan CG11920 CG11920 mRpS18C mRpS18C CG4866 CG4866 CG4679 CG4679 mRpL18 mRpL18 mRpS11 mRpS11 mRpS6 mRpS6 mRpS7 mRpS7 mRpL16 mRpL16 CG17652 CG17652 RpLP0 RpLP0 RpL9 RpL9 RpS9 RpS9 CG3735 CG3735 RpS5a RpS5a RpL5 RpL5 Pop4 Pop4 CG3862 CG3862 CG9253 CG9253 mTerf3 mTerf3 CG6712 CG6712 La La CG3527 CG3527 RpS14a RpS14a RpS14b RpS14b CG1785 CG1785 RpL23 RpL23 RpL12 RpL12 CG11583 CG11583
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CG5589Uncharacterized protein; RNA helicase activity; RNA binding; ATP binding. It is involved in the biological process described with: maturation of SSU-rRNA; Belongs to the DEAD box helicase family. (594 aa)
mRpL20Mitochondrial ribosomal protein L20; rRNA binding; structural constituent of ribosome. It is involved in the biological process described with: mitochondrial translation; translation; ribosomal large subunit assembly; Belongs to the bacterial ribosomal protein bL20 family. (150 aa)
CG4901RE48269p; CG4901 encodes an ATP-dependent RNA helicase involved in neurogenesis and spliceosomal complex disassembly. (694 aa)
RpS13Ribosomal protein S13 (RpS13) encodes a structural constituent of ribosomes; Belongs to the universal ribosomal protein uS15 family. (151 aa)
mRpS18AMitochondrial ribosomal protein S18A; Small ribosomal subunit rRNA binding; structural constituent of ribosome. It is involved in the biological process described with: mitochondrial translation; translation. (155 aa)
CG7488GH26602p; rRNA binding; GTP binding; ribosomal small subunit binding. It is involved in the biological process described with: ribosomal small subunit assembly. (373 aa)
mRpL1139S ribosomal protein L11, mitochondrial; Structural constituent of ribosome; large ribosomal subunit rRNA binding; rRNA binding. It is involved in the biological process described with: mitochondrial translation; translation; ribosomal large subunit assembly; Belongs to the universal ribosomal protein uL11 family. (196 aa)
RpS5b40S ribosomal protein S5b; rRNA binding; structural constituent of ribosome; mRNA binding. It is involved in the biological process described with: cytoplasmic translation; ribosomal small subunit assembly; translation; Belongs to the universal ribosomal protein uS7 family. (230 aa)
Non3Ribosome production factor 2 homolog; Required for normal assembly of the mitotic spindle. May be involved in both centrosome-dependent and centrosome-independent spindle assembly programs; Belongs to the RPF2 family. (320 aa)
ppanProtein Peter pan; Required for initiation of larval growth and normal mitotic growth but is not absolutely required for general biosynthesis or DNA replication. Required for progression of normal oogenesis and maturation of some imaginal tissues into adult structures. (460 aa)
CG11920FI08810p; snoRNA binding. It is involved in the biological process described with: rRNA processing. (298 aa)
mRpS18CMitochondrial ribosomal protein S18C (mRpS18C) encodes a component of the small subunit of mitochondrial ribosomes, which translate mRNAs encoded by the mitochondrial genome. (140 aa)
CG4866RE57564p; snoRNA binding; rRNA binding. It is involved in the biological process described with: rRNA processing. (181 aa)
CG4679Protein PTCD3 homolog, mitochondrial; Mitochondrial protein that may have a role in mitochondrial translation; Belongs to the mitochondrion-specific ribosomal protein mS39 family. (652 aa)
mRpL18Mitochondrial ribosomal protein L18; 5S rRNA binding; structural constituent of ribosome. It is involved in the biological process described with: translation; mitochondrial translation. (186 aa)
mRpS11Mitochondrial ribosomal protein S11; mRNA 5'-UTR binding; structural constituent of ribosome; small ribosomal subunit rRNA binding. It is involved in the biological process described with: ribosomal small subunit assembly; translation; mitochondrial translation; maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA). (200 aa)
mRpS6Probable 28S ribosomal protein S6, mitochondrial; Structural constituent of ribosome; small ribosomal subunit rRNA binding. It is involved in the biological process described with: mitochondrial translation; translation; Belongs to the bacterial ribosomal protein bS6 family. (147 aa)
mRpS728S ribosomal protein S7, mitochondrial; Structural constituent of ribosome; rRNA binding; mRNA binding. It is involved in the biological process described with: mitochondrial translation; translation; ribosomal small subunit assembly; Belongs to the universal ribosomal protein uS7 family. (218 aa)
mRpL16Mitochondrial ribosomal protein L16, isoform A; Structural constituent of ribosome; rRNA binding. It is involved in the biological process described with: mitochondrial translation. (243 aa)
CG17652Uncharacterized protein, isoform A; Small ribosomal subunit rRNA binding. (244 aa)
RpLP060S acidic ribosomal protein P0; Ribosomal protein P0 is the functional equivalent of E.coli protein L10; Belongs to the universal ribosomal protein uL10 family. (317 aa)
RpL9Ribosomal protein L9 (RpL9) encodes a ribosomal structural constituent; Belongs to the universal ribosomal protein uL6 family. (190 aa)
RpS9Ribosomal protein S9 (RpS9) encodes a structural constituent of ribosomes. (195 aa)
CG3735Uncharacterized protein, isoform A; U3 snoRNA binding; rRNA binding. It is involved in the biological process described with: maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA). (700 aa)
RpS5aRibosomal protein S5a (RpS5a) encodes a structural constituent of ribosomes; Belongs to the universal ribosomal protein uS7 family. (228 aa)
RpL560S ribosomal protein L5; Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules. The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain. The nascent polypeptides leave the ribosome through [...] (299 aa)
Pop4Ribonuclease P protein subunit p29; Component of ribonuclease P, a ribonucleoprotein complex that generates mature tRNA molecules by cleaving their 5'-ends. (206 aa)
CG3862Uncharacterized protein. (454 aa)
CG9253FI20110p1; RNA binding; RNA helicase activity; ATP binding. It is involved in the biological process described with: rRNA processing; Belongs to the DEAD box helicase family. (507 aa)
mTerf3Transcription termination factor 3, mitochondrial; Binds promoter DNA and regulates initiation of transcription (By similarity). Regulator of mitochondrial ribosome biogenesis and translation that is essential for development. Required for normal mitochondrial transcription and translation. Required for assembly of mitochondrial respiratory complexes and normal mitochondrial function. Maintains 16S rRNA levels and functions in mitochondrial ribosome assembly by regulating the biogenesis of the 39S ribosomal subunit. (354 aa)
CG6712Probable ribosome production factor 1; May be required for ribosome biogenesis. (394 aa)
LaLa protein homolog; May be involved in transcription termination by RNA polymerase III. Binds RNA and DNA. Binds to precursors of RNA polymerase III transcripts. May play a specialized role during fly development. (390 aa)
CG3527Ribosomal RNA small subunit methyltransferase NEP1; S-adenosyl-L-methionine-dependent pseudouridine N(1)- methyltransferase that methylates a pseudouridine in 18S rRNA. Involved the biosynthesis of the hypermodified N1-methyl-N3-(3-amino-3- carboxypropyl) pseudouridine (m1acp3-Psi) conserved in eukaryotic 18S rRNA. Has also an essential role in 40S ribosomal subunit biogenesis independent on its methyltransferase activity, facilitating the incorporation of ribosomal protein S19 during the formation of pre- ribosomes; Belongs to the class IV-like SAM-binding methyltransferase superfamil [...] (252 aa)
RpS14a40S ribosomal protein S14a; Small ribosomal subunit rRNA binding; structural constituent of ribosome; mRNA 5'-UTR binding. It is involved in the biological process described with: cytoplasmic translation; maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); translation; ribosomal small subunit assembly; Belongs to the universal ribosomal protein uS11 family. (151 aa)
RpS14bmRNA 5'-UTR binding; structural constituent of ribosome; small ribosomal subunit rRNA binding. It is involved in the biological process described with: maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); cytoplasmic translation; ribosomal small subunit assembly; translation. (151 aa)
CG1785Ribosome biogenesis protein NOP53; May play a role in ribosome biogenesis, being required for integration of the 5S RNP into the ribosomal large subunit. Belongs to the NOP53 family. (478 aa)
RpL2360S ribosomal protein L23; Large ribosomal subunit rRNA binding; structural constituent of ribosome; myosin binding. It is involved in the biological process described with: translation; cytoplasmic translation; Belongs to the universal ribosomal protein uL14 family. (140 aa)
RpL12Ribosomal protein L12 (RpL12) encodes a protein of the large subunit of the ribosome. It regulates transcription of ribosomal proteins and ribosome biogenesis genes as well as interacting with the Enhancer of Trithorax and Polycomb protein encoded by corto. (165 aa)
CG11583Ribosome biogenesis protein BRX1 homolog; Required for biogenesis of the 60S ribosomal subunit. Belongs to the BRX1 family. (356 aa)
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
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