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RpS17 RpS17 RpS11 RpS11 RpS23 RpS23 RpS25 RpS25 RpS27A RpS27A RpS5b RpS5b RpS20 RpS20 RpS15 RpS15 RpS18 RpS18 RpS28a RpS28a RpS10a RpS10a RpS19b RpS19b RpS27 RpS27 RpS26 RpS26 RpS13 RpS13 RpS4 RpS4 RpS3 RpS3 RpS30 RpS30 RpS12 RpS12 RpS10b RpS10b RpS21 RpS21 RpS15Aa RpS15Aa RpS6 RpS6 RpS14b RpS14b RpS14a RpS14a sta sta RpS24 RpS24 RpS3A RpS3A RpS2 RpS2 RpS29 RpS29 RpS28b RpS28b RpS5a RpS5a RpS16 RpS16 RpS9 RpS9 RpS19a RpS19a RpS28-like RpS28-like RpS8 RpS8 RpS7 RpS7 RpS15Ab RpS15Ab
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
RpS17Ribosomal protein S17 (RpS17) encodes an essential component of the ribosomal 40S subunit. RpS17 mutants have dominant, haploinsufficient effects on cellular and organismal growth rate, and on bristle size; Belongs to the eukaryotic ribosomal protein eS17 family. (131 aa)
RpS1140S ribosomal protein S11; Structural constituent of ribosome. It is involved in the biological process described with: translation; cytoplasmic translation; Belongs to the universal ribosomal protein uS17 family. (155 aa)
RpS2340S ribosomal protein S23; Structural constituent of ribosome. It is involved in the biological process described with: translation; cytoplasmic translation. (143 aa)
RpS2540S ribosomal protein S25; Structural constituent of ribosome. It is involved in the biological process described with: cytoplasmic translation; Belongs to the eukaryotic ribosomal protein eS25 family. (117 aa)
RpS27AUbiquitin-40S ribosomal protein S27a; Ubiquitin exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-48-linked is involve [...] (156 aa)
RpS5b40S ribosomal protein S5b; rRNA binding; structural constituent of ribosome; mRNA binding. It is involved in the biological process described with: cytoplasmic translation; ribosomal small subunit assembly; translation; Belongs to the universal ribosomal protein uS7 family. (230 aa)
RpS2040S ribosomal protein S20; RNA binding; structural constituent of ribosome. It is involved in the biological process described with: cytoplasmic translation; translation. (120 aa)
RpS15Ribosomal protein S15 (RpS15) encodes a protein that plays a role in assembly, structure and function of the ribosome and functions in protein synthesis. It is phosphorylated by the kinase encoded by Lrrk, causing protein synthesis upregulation; Belongs to the universal ribosomal protein uS19 family. (148 aa)
RpS18Ribosomal protein S18 (RpS18) encodes a ribosomal protein located at the top of the head of the 40S subunit and contacts several helices of the 18S rRNA. (152 aa)
RpS28aRibosomal protein S28a; Structural constituent of ribosome. It is involved in the biological process described with: ribosomal small subunit assembly; translation; wing disc development; maturation of SSU-rRNA; cytoplasmic translation. (64 aa)
RpS10a40S ribosomal protein S10a; Structural constituent of ribosome; RNA binding. It is involved in the biological process described with: ribosomal small subunit assembly; cytoplasmic translation. (163 aa)
RpS19b40S ribosomal protein S19b; RNA binding; structural constituent of ribosome. It is involved in the biological process described with: cytoplasmic translation; ribosomal small subunit assembly; translation; Belongs to the eukaryotic ribosomal protein eS19 family. (155 aa)
RpS2740S ribosomal protein S27; RNA binding; structural constituent of ribosome. It is involved in the biological process described with: cytoplasmic translation; ribosomal small subunit assembly; translation. (84 aa)
RpS2640S ribosomal protein S26; mRNA binding; structural constituent of ribosome. It is involved in the biological process described with: cytoplasmic translation. (114 aa)
RpS13Ribosomal protein S13 (RpS13) encodes a structural constituent of ribosomes; Belongs to the universal ribosomal protein uS15 family. (151 aa)
RpS4Ribosomal protein S4 (RpS4) encodes a structural constituent of ribosomes; Belongs to the eukaryotic ribosomal protein eS4 family. (261 aa)
RpS3Ribosomal protein S3 (RpS3) encodes a component of the small subunit of cytoplasmic ribosomes, which translate mRNAs encoded by the nuclear genome. RpS3 is haploinsufficient - heterozygous mutants display the 'Minute' phenotype, characterized by a slower developmental rate and small adult bristles. The product of RpS3 also contains a DNA lyase activity and functions in DNA repair. (246 aa)
RpS3040S ribosomal protein S30; Structural constituent of ribosome. It is involved in the biological process described with: translation; cytoplasmic translation; Belongs to the eukaryotic ribosomal protein eS30 family. (132 aa)
RpS12Ribosomal protein S12 (RpS12) is an essential gene encoding a protein component of the cytoplasmic small ribosomal subunit. (139 aa)
RpS10bRibosomal protein S10b (RpS10b) encodes a structural constituent of ribosomes; Belongs to the eukaryotic ribosomal protein eS10 family. (160 aa)
RpS2140S ribosomal protein S21; May be an associated component of the ribosome rather than a core structural subunit. May act as a translation initiation factor. Has a role in regulation of cell proliferation in the hematopoietic organs and the imaginal disks of larva. (83 aa)
RpS15Aa40S ribosomal protein S15Aa; Structural constituent of ribosome. It is involved in the biological process described with: cytoplasmic translation; translation; Belongs to the universal ribosomal protein uS8 family. (130 aa)
RpS640S ribosomal protein S6; May play an important role in controlling cell growth and proliferation through the selective translation of particular classes of mRNA. (248 aa)
RpS14bmRNA 5'-UTR binding; structural constituent of ribosome; small ribosomal subunit rRNA binding. It is involved in the biological process described with: maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); cytoplasmic translation; ribosomal small subunit assembly; translation. (151 aa)
RpS14a40S ribosomal protein S14a; Small ribosomal subunit rRNA binding; structural constituent of ribosome; mRNA 5'-UTR binding. It is involved in the biological process described with: cytoplasmic translation; maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); translation; ribosomal small subunit assembly; Belongs to the universal ribosomal protein uS11 family. (151 aa)
sta40S ribosomal protein SA; Required for the assembly and/or stability of the 40S ribosomal subunit. Required for the processing of the 20S rRNA- precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits. Required during oogenesis and imaginal development. Belongs to the universal ribosomal protein uS2 family. (270 aa)
RpS24Ribosomal protein S24 (RpS24) encodes an essential component of the small ribosomal subunit that functions in protein synthesis. It is classified as a 'Minute' gene as heterozygous mutants exhibit a slower developmental rate and small adult bristles; Belongs to the eukaryotic ribosomal protein eS24 family. (131 aa)
RpS3ARibosomal protein S3A (RpS3A) encodes an essential component of the small ribosomal subunit that functions in protein synthesis. It is classified as a 'Minute' gene as heterozygous mutants exhibit a slower developmental rate and small adult bristles; Belongs to the eukaryotic ribosomal protein eS1 family. (268 aa)
RpS2Ribosomal protein S2 (RpS2) encodes a highly conserved component of the 40S ribolomal comlex. RpS2 product controls the assembly and nuclear export of the pre-ribosome and appears to have a specific function during oogenesis. (267 aa)
RpS2940S ribosomal protein S29; Zinc ion binding; structural constituent of ribosome. It is involved in the biological process described with: cytoplasmic translation. (56 aa)
RpS28b40S ribosomal protein S28; Structural constituent of ribosome. It is involved in the biological process described with: ribosomal small subunit assembly; translation; maturation of SSU-rRNA; cytoplasmic translation; Belongs to the eukaryotic ribosomal protein eS28 family. (65 aa)
RpS5aRibosomal protein S5a (RpS5a) encodes a structural constituent of ribosomes; Belongs to the universal ribosomal protein uS7 family. (228 aa)
RpS1640S ribosomal protein S16; Structural constituent of ribosome; RNA binding. It is involved in the biological process described with: maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); cytoplasmic translation; translation; Belongs to the universal ribosomal protein uS9 family. (148 aa)
RpS9Ribosomal protein S9 (RpS9) encodes a structural constituent of ribosomes. (195 aa)
RpS19aRibosomal protein S19a (RpS19a) encodes a structural constituent of ribosomes; Belongs to the eukaryotic ribosomal protein eS19 family. (156 aa)
RpS28-likeRibosomal protein S28-like; Structural constituent of ribosome. It is involved in the biological process described with: ribosomal small subunit assembly; translation; maturation of SSU-rRNA; cytoplasmic translation. (76 aa)
RpS8Ribosomal protein S8 (RpS8) encodes a structural constituent of ribosomes that is involved in larval lymph gland hemopoiesis; Belongs to the eukaryotic ribosomal protein eS8 family. (208 aa)
RpS740S ribosomal protein S7; Structural constituent of ribosome. It is involved in the biological process described with: translation; ribosomal small subunit biogenesis; cytoplasmic translation; rRNA processing; Belongs to the eukaryotic ribosomal protein eS7 family. (194 aa)
RpS15Ab40S ribosomal protein S15Ab; Structural constituent of ribosome. It is involved in the biological process described with: translation; cytoplasmic translation; Belongs to the universal ribosomal protein uS8 family. (130 aa)
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
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