(18 nodes) Autophagosome maturation network (Musca domestica)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

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a 3D structure is known or predicted

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Predicted Interactions

gene neighborhood

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Your Input:
	T1PBL3_MUSDO	Polycystin cation channel. (656 aa)
	A0A1I8NI14	Vacuolar protein sorting-associated protein 16 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes. Belongs to the VPS16 family. (841 aa)
	A0A1I8NCQ4	t-SNARE coiled-coil homology domain-containing protein. (312 aa)
	A0A1I8N6T0	CNH domain-containing protein. (891 aa)
	A0A1I8MUL7	Uncharacterized protein; Belongs to the AAA ATPase family. (359 aa)
	A0A1I8MK38	Uncharacterized protein. (269 aa)
	A0A1I8MIC1	Uncharacterized protein; Belongs to the synaptobrevin family. (219 aa)
	A0A1I8MF28	Uncharacterized protein. (174 aa)
	A0A1I8M583	Uncharacterized protein; Belongs to the STXBP/unc-18/SEC1 family. (600 aa)
	A0A1I8MDE7	Pep3_Vps18 domain-containing protein. (992 aa)
	A0A1I8M7W2	Uncharacterized protein. (1866 aa)
	A0A1I8M5E1	Vacuolar protein sorting-associated protein 41 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport pathways; Belongs to the VPS41 family. (837 aa)
	A0A1I8N3I1	V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. (858 aa)
	A0A1I8N322	VWFA domain-containing protein. (1246 aa)
	A0A1I8MYP7	RING-type domain-containing protein. (916 aa)
	T1PLV6_MUSDO	ATPase family associated protein; Belongs to the AAA ATPase family. (440 aa)
	T1PID4_MUSDO	Vacuolar protein sorting-associated protein 28 homolog; Component of the ESCRT-I complex (endosomal sorting complex required for transport I), a regulator of vesicular trafficking process. (209 aa)
	T1PEY4_MUSDO	ATPase family associated protein; Belongs to the AAA ATPase family. (801 aa)

Your Current Organism:

Musca domestica

NCBI taxonomy Id: 7370
Other names: house fly

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A0A1I8M583	A0A1I8M5E1	A0A1I8M583	A0A1I8M5E1	Uncharacterized protein; Belongs to the STXBP/unc-18/SEC1 family.	Vacuolar protein sorting-associated protein 41 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport pathways; Belongs to the VPS41 family.	0.907
A0A1I8M583	A0A1I8MDE7	A0A1I8M583	A0A1I8MDE7	Uncharacterized protein; Belongs to the STXBP/unc-18/SEC1 family.	Pep3_Vps18 domain-containing protein.	0.921
A0A1I8M583	A0A1I8MIC1	A0A1I8M583	A0A1I8MIC1	Uncharacterized protein; Belongs to the STXBP/unc-18/SEC1 family.	Uncharacterized protein; Belongs to the synaptobrevin family.	0.807
A0A1I8M583	A0A1I8MYP7	A0A1I8M583	A0A1I8MYP7	Uncharacterized protein; Belongs to the STXBP/unc-18/SEC1 family.	RING-type domain-containing protein.	0.908
A0A1I8M583	A0A1I8N6T0	A0A1I8M583	A0A1I8N6T0	Uncharacterized protein; Belongs to the STXBP/unc-18/SEC1 family.	CNH domain-containing protein.	0.915
A0A1I8M583	A0A1I8NCQ4	A0A1I8M583	A0A1I8NCQ4	Uncharacterized protein; Belongs to the STXBP/unc-18/SEC1 family.	t-SNARE coiled-coil homology domain-containing protein.	0.588
A0A1I8M583	A0A1I8NI14	A0A1I8M583	A0A1I8NI14	Uncharacterized protein; Belongs to the STXBP/unc-18/SEC1 family.	Vacuolar protein sorting-associated protein 16 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes. Belongs to the VPS16 family.	0.922
A0A1I8M5E1	A0A1I8M583	A0A1I8M5E1	A0A1I8M583	Vacuolar protein sorting-associated protein 41 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport pathways; Belongs to the VPS41 family.	Uncharacterized protein; Belongs to the STXBP/unc-18/SEC1 family.	0.907
A0A1I8M5E1	A0A1I8MDE7	A0A1I8M5E1	A0A1I8MDE7	Vacuolar protein sorting-associated protein 41 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport pathways; Belongs to the VPS41 family.	Pep3_Vps18 domain-containing protein.	0.995
A0A1I8M5E1	A0A1I8MYP7	A0A1I8M5E1	A0A1I8MYP7	Vacuolar protein sorting-associated protein 41 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport pathways; Belongs to the VPS41 family.	RING-type domain-containing protein.	0.995
A0A1I8M5E1	A0A1I8N6T0	A0A1I8M5E1	A0A1I8N6T0	Vacuolar protein sorting-associated protein 41 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport pathways; Belongs to the VPS41 family.	CNH domain-containing protein.	0.995
A0A1I8M5E1	A0A1I8NCQ4	A0A1I8M5E1	A0A1I8NCQ4	Vacuolar protein sorting-associated protein 41 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport pathways; Belongs to the VPS41 family.	t-SNARE coiled-coil homology domain-containing protein.	0.940
A0A1I8M5E1	A0A1I8NI14	A0A1I8M5E1	A0A1I8NI14	Vacuolar protein sorting-associated protein 41 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport pathways; Belongs to the VPS41 family.	Vacuolar protein sorting-associated protein 16 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes. Belongs to the VPS16 family.	0.997
A0A1I8M7W2	A0A1I8N6T0	A0A1I8M7W2	A0A1I8N6T0	Uncharacterized protein.	CNH domain-containing protein.	0.433
A0A1I8M7W2	T1PBL3_MUSDO	A0A1I8M7W2	T1PBL3	Uncharacterized protein.	Polycystin cation channel.	0.400
A0A1I8MDE7	A0A1I8M583	A0A1I8MDE7	A0A1I8M583	Pep3_Vps18 domain-containing protein.	Uncharacterized protein; Belongs to the STXBP/unc-18/SEC1 family.	0.921
A0A1I8MDE7	A0A1I8M5E1	A0A1I8MDE7	A0A1I8M5E1	Pep3_Vps18 domain-containing protein.	Vacuolar protein sorting-associated protein 41 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport pathways; Belongs to the VPS41 family.	0.995
A0A1I8MDE7	A0A1I8MF28	A0A1I8MDE7	A0A1I8MF28	Pep3_Vps18 domain-containing protein.	Uncharacterized protein.	0.539
A0A1I8MDE7	A0A1I8MIC1	A0A1I8MDE7	A0A1I8MIC1	Pep3_Vps18 domain-containing protein.	Uncharacterized protein; Belongs to the synaptobrevin family.	0.527
A0A1I8MDE7	A0A1I8MYP7	A0A1I8MDE7	A0A1I8MYP7	Pep3_Vps18 domain-containing protein.	RING-type domain-containing protein.	0.995