(5 nodes) Drug-mediated inhibition of ERBB2 signaling, and Translational attenuation network (Sinocyclocheilus grahami)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ENSSGRP00000012813	Heat shock protein HSP 90-alpha. (115 aa)
	ENSSGRP00000034429	Cell division cycle 37 homolog (S. cerevisiae). (352 aa)
	ENSSGRP00000037894	Serine/threonine-protein phosphatase 5. (430 aa)
	Trap1	Heat shock protein 75 kDa, mitochondrial. (495 aa)
	ENSSGRP00000083814	annotation not available (84 aa)

Your Current Organism:

Sinocyclocheilus grahami

NCBI taxonomy Id: 75366
Other names: S. grahami

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSSGRP00000012813	ENSSGRP00000034429	ENSSGRP00000012813	ENSSGRP00000034429	Heat shock protein HSP 90-alpha.	Cell division cycle 37 homolog (S. cerevisiae).	0.909
ENSSGRP00000012813	ENSSGRP00000037894	ENSSGRP00000012813	ENSSGRP00000037894	Heat shock protein HSP 90-alpha.	Serine/threonine-protein phosphatase 5.	0.927
ENSSGRP00000012813	ENSSGRP00000083814	ENSSGRP00000012813	ENSSGRP00000083814	Heat shock protein HSP 90-alpha.	annotation not available	0.812
ENSSGRP00000012813	Trap1	ENSSGRP00000012813	ENSSGRP00000048970	Heat shock protein HSP 90-alpha.	Heat shock protein 75 kDa, mitochondrial.	0.549
ENSSGRP00000034429	ENSSGRP00000012813	ENSSGRP00000034429	ENSSGRP00000012813	Cell division cycle 37 homolog (S. cerevisiae).	Heat shock protein HSP 90-alpha.	0.909
ENSSGRP00000034429	ENSSGRP00000037894	ENSSGRP00000034429	ENSSGRP00000037894	Cell division cycle 37 homolog (S. cerevisiae).	Serine/threonine-protein phosphatase 5.	0.862
ENSSGRP00000034429	ENSSGRP00000083814	ENSSGRP00000034429	ENSSGRP00000083814	Cell division cycle 37 homolog (S. cerevisiae).	annotation not available	0.681
ENSSGRP00000034429	Trap1	ENSSGRP00000034429	ENSSGRP00000048970	Cell division cycle 37 homolog (S. cerevisiae).	Heat shock protein 75 kDa, mitochondrial.	0.800
ENSSGRP00000037894	ENSSGRP00000012813	ENSSGRP00000037894	ENSSGRP00000012813	Serine/threonine-protein phosphatase 5.	Heat shock protein HSP 90-alpha.	0.927
ENSSGRP00000037894	ENSSGRP00000034429	ENSSGRP00000037894	ENSSGRP00000034429	Serine/threonine-protein phosphatase 5.	Cell division cycle 37 homolog (S. cerevisiae).	0.862
ENSSGRP00000037894	ENSSGRP00000083814	ENSSGRP00000037894	ENSSGRP00000083814	Serine/threonine-protein phosphatase 5.	annotation not available	0.902
ENSSGRP00000037894	Trap1	ENSSGRP00000037894	ENSSGRP00000048970	Serine/threonine-protein phosphatase 5.	Heat shock protein 75 kDa, mitochondrial.	0.865
ENSSGRP00000083814	ENSSGRP00000012813	ENSSGRP00000083814	ENSSGRP00000012813	annotation not available	Heat shock protein HSP 90-alpha.	0.812
ENSSGRP00000083814	ENSSGRP00000034429	ENSSGRP00000083814	ENSSGRP00000034429	annotation not available	Cell division cycle 37 homolog (S. cerevisiae).	0.681
ENSSGRP00000083814	ENSSGRP00000037894	ENSSGRP00000083814	ENSSGRP00000037894	annotation not available	Serine/threonine-protein phosphatase 5.	0.902
ENSSGRP00000083814	Trap1	ENSSGRP00000083814	ENSSGRP00000048970	annotation not available	Heat shock protein 75 kDa, mitochondrial.	0.812
Trap1	ENSSGRP00000012813	ENSSGRP00000048970	ENSSGRP00000012813	Heat shock protein 75 kDa, mitochondrial.	Heat shock protein HSP 90-alpha.	0.549
Trap1	ENSSGRP00000034429	ENSSGRP00000048970	ENSSGRP00000034429	Heat shock protein 75 kDa, mitochondrial.	Cell division cycle 37 homolog (S. cerevisiae).	0.800
Trap1	ENSSGRP00000037894	ENSSGRP00000048970	ENSSGRP00000037894	Heat shock protein 75 kDa, mitochondrial.	Serine/threonine-protein phosphatase 5.	0.865
Trap1	ENSSGRP00000083814	ENSSGRP00000048970	ENSSGRP00000083814	Heat shock protein 75 kDa, mitochondrial.	annotation not available	0.812