(5 nodes) Inflammatory response, and Neutrophil mediated immunity network (Sinocyclocheilus grahami)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	irak1	Interleukin-1 receptor-associated kinase 1 isoform X1. (704 aa)
	irak4	Interleukin-1 receptor-associated kinase 4. (492 aa)
	ENSSGRP00000059767	Toll-interacting protein-like. (278 aa)
	LOC107550181	Toll-interacting protein. (279 aa)
	LOC107584943	Myeloid differentiation primary response protein MyD88-like. (284 aa)

Your Current Organism:

Sinocyclocheilus grahami

NCBI taxonomy Id: 75366
Other names: S. grahami

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSSGRP00000059767	LOC107550181	ENSSGRP00000059767	ENSSGRP00000063175	Toll-interacting protein-like.	Toll-interacting protein.	0.900
ENSSGRP00000059767	LOC107584943	ENSSGRP00000059767	ENSSGRP00000082576	Toll-interacting protein-like.	Myeloid differentiation primary response protein MyD88-like.	0.969
ENSSGRP00000059767	irak1	ENSSGRP00000059767	ENSSGRP00000036935	Toll-interacting protein-like.	Interleukin-1 receptor-associated kinase 1 isoform X1.	0.925
ENSSGRP00000059767	irak4	ENSSGRP00000059767	ENSSGRP00000044806	Toll-interacting protein-like.	Interleukin-1 receptor-associated kinase 4.	0.927
LOC107550181	ENSSGRP00000059767	ENSSGRP00000063175	ENSSGRP00000059767	Toll-interacting protein.	Toll-interacting protein-like.	0.900
LOC107550181	LOC107584943	ENSSGRP00000063175	ENSSGRP00000082576	Toll-interacting protein.	Myeloid differentiation primary response protein MyD88-like.	0.969
LOC107550181	irak1	ENSSGRP00000063175	ENSSGRP00000036935	Toll-interacting protein.	Interleukin-1 receptor-associated kinase 1 isoform X1.	0.925
LOC107550181	irak4	ENSSGRP00000063175	ENSSGRP00000044806	Toll-interacting protein.	Interleukin-1 receptor-associated kinase 4.	0.927
LOC107584943	ENSSGRP00000059767	ENSSGRP00000082576	ENSSGRP00000059767	Myeloid differentiation primary response protein MyD88-like.	Toll-interacting protein-like.	0.969
LOC107584943	LOC107550181	ENSSGRP00000082576	ENSSGRP00000063175	Myeloid differentiation primary response protein MyD88-like.	Toll-interacting protein.	0.969
LOC107584943	irak1	ENSSGRP00000082576	ENSSGRP00000036935	Myeloid differentiation primary response protein MyD88-like.	Interleukin-1 receptor-associated kinase 1 isoform X1.	0.998
LOC107584943	irak4	ENSSGRP00000082576	ENSSGRP00000044806	Myeloid differentiation primary response protein MyD88-like.	Interleukin-1 receptor-associated kinase 4.	0.999
irak1	ENSSGRP00000059767	ENSSGRP00000036935	ENSSGRP00000059767	Interleukin-1 receptor-associated kinase 1 isoform X1.	Toll-interacting protein-like.	0.925
irak1	LOC107550181	ENSSGRP00000036935	ENSSGRP00000063175	Interleukin-1 receptor-associated kinase 1 isoform X1.	Toll-interacting protein.	0.925
irak1	LOC107584943	ENSSGRP00000036935	ENSSGRP00000082576	Interleukin-1 receptor-associated kinase 1 isoform X1.	Myeloid differentiation primary response protein MyD88-like.	0.998
irak1	irak4	ENSSGRP00000036935	ENSSGRP00000044806	Interleukin-1 receptor-associated kinase 1 isoform X1.	Interleukin-1 receptor-associated kinase 4.	0.999
irak4	ENSSGRP00000059767	ENSSGRP00000044806	ENSSGRP00000059767	Interleukin-1 receptor-associated kinase 4.	Toll-interacting protein-like.	0.927
irak4	LOC107550181	ENSSGRP00000044806	ENSSGRP00000063175	Interleukin-1 receptor-associated kinase 4.	Toll-interacting protein.	0.927
irak4	LOC107584943	ENSSGRP00000044806	ENSSGRP00000082576	Interleukin-1 receptor-associated kinase 4.	Myeloid differentiation primary response protein MyD88-like.	0.999
irak4	irak1	ENSSGRP00000044806	ENSSGRP00000036935	Interleukin-1 receptor-associated kinase 4.	Interleukin-1 receptor-associated kinase 1 isoform X1.	0.999