(7 nodes) Centromeric DNA binding network (Sinocyclocheilus grahami)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ENSSGRP00000098514	Centromere/kinetochore protein zw10 homolog. (580 aa)
	ENSSGRP00000000137	DNA mismatch repair protein Mlh3-like isoform X1. (107 aa)
	ENSSGRP00000024222	mutL homolog 3 (E. coli). (404 aa)
	LOC107551653	Centromere/kinetochore protein zw10 homolog isoform X1. (786 aa)
	LOC107550043	DNA mismatch repair protein Msh2-like. (936 aa)
	LOC107582784	DNA mismatch repair protein Msh2-like. (946 aa)
	ENSSGRP00000098179	annotation not available (205 aa)

Your Current Organism:

Sinocyclocheilus grahami

NCBI taxonomy Id: 75366
Other names: S. grahami

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structured XML interaction data, according to the 'PSI-MI' data standard

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node degree of proteins in your network (given the current score cut-off)

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a flat-file format describing the coordinates and colors of nodes in the network

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSSGRP00000000137	LOC107550043	ENSSGRP00000000137	ENSSGRP00000041943	DNA mismatch repair protein Mlh3-like isoform X1.	DNA mismatch repair protein Msh2-like.	0.952
ENSSGRP00000000137	LOC107582784	ENSSGRP00000000137	ENSSGRP00000087509	DNA mismatch repair protein Mlh3-like isoform X1.	DNA mismatch repair protein Msh2-like.	0.952
ENSSGRP00000024222	LOC107550043	ENSSGRP00000024222	ENSSGRP00000041943	mutL homolog 3 (E. coli).	DNA mismatch repair protein Msh2-like.	0.935
ENSSGRP00000024222	LOC107582784	ENSSGRP00000024222	ENSSGRP00000087509	mutL homolog 3 (E. coli).	DNA mismatch repair protein Msh2-like.	0.935
ENSSGRP00000098179	LOC107550043	ENSSGRP00000098179	ENSSGRP00000041943	annotation not available	DNA mismatch repair protein Msh2-like.	0.935
ENSSGRP00000098179	LOC107582784	ENSSGRP00000098179	ENSSGRP00000087509	annotation not available	DNA mismatch repair protein Msh2-like.	0.935
LOC107550043	ENSSGRP00000000137	ENSSGRP00000041943	ENSSGRP00000000137	DNA mismatch repair protein Msh2-like.	DNA mismatch repair protein Mlh3-like isoform X1.	0.952
LOC107550043	ENSSGRP00000024222	ENSSGRP00000041943	ENSSGRP00000024222	DNA mismatch repair protein Msh2-like.	mutL homolog 3 (E. coli).	0.935
LOC107550043	ENSSGRP00000098179	ENSSGRP00000041943	ENSSGRP00000098179	DNA mismatch repair protein Msh2-like.	annotation not available	0.935
LOC107582784	ENSSGRP00000000137	ENSSGRP00000087509	ENSSGRP00000000137	DNA mismatch repair protein Msh2-like.	DNA mismatch repair protein Mlh3-like isoform X1.	0.952
LOC107582784	ENSSGRP00000024222	ENSSGRP00000087509	ENSSGRP00000024222	DNA mismatch repair protein Msh2-like.	mutL homolog 3 (E. coli).	0.935
LOC107582784	ENSSGRP00000098179	ENSSGRP00000087509	ENSSGRP00000098179	DNA mismatch repair protein Msh2-like.	annotation not available	0.935