(48 nodes) Positive regulation of BMP signaling pathway network (Sinocyclocheilus grahami)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	fkbp8	Peptidyl-prolyl cis-trans isomerase FKBP8. (403 aa)
	ENSSGRP00000068648	Bone morphogenetic protein 1-like. (977 aa)
	LOC107571685	Beta-1,4-galactosyltransferase 5-like. (293 aa)
	ENSSGRP00000076363	Mothers against decapentaplegic homolog 4-like isoform X1. (573 aa)
	Ilk	Integrin-linked protein kinase. (434 aa)
	LOC107551739	Cadherin 5, type 2, VE-cadherin. (769 aa)
	ENSSGRP00000087559	Integrin-linked kinase. (442 aa)
	LOC107553124	Bone morphogenetic protein 1-like. (955 aa)
	ENSSGRP00000089762	Si:dkey-222b8.1. (527 aa)
	ENSSGRP00000091411	Ring finger protein 165a. (322 aa)
	ENSSGRP00000098989	Mothers against decapentaplegic homolog 4-like. (169 aa)
	LOC107591552	Dorsal-ventral patterning tolloid-like protein 1 isoform X1. (1022 aa)
	LOC107595463	Growth/differentiation factor 5-like. (491 aa)
	ENSSGRP00000104891	Mothers against decapentaplegic homolog 4-like. (571 aa)
	LOC107593250	Bone morphogenetic protein 2-like. (411 aa)
	bmpr2	Bone morphogenetic protein receptor type-2 isoform X1. (1064 aa)
	LOC107600621	Growth/differentiation factor 6-A. (405 aa)
	LOC107562012	Serine/threonine-protein phosphatase 4 catalytic subunit B isoform X1. (312 aa)
	bmp2	Bone morphogenetic protein 2. (388 aa)
	ENSSGRP00000060040	Peptidyl-prolyl cis-trans isomerase FKBP8-like. (215 aa)
	ENSSGRP00000060520	Nuclear mitotic apparatus protein 1. (1727 aa)
	ENSSGRP00000064233	Peptidyl-prolyl cis-trans isomerase FKBP8-like. (130 aa)
	LOC107593012	Bone morphogenetic protein receptor type-2-like. (1085 aa)
	ENSSGRP00000066664	Muscle segment homeobox 1a. (150 aa)
	LOC107570245	Insulin-like growth factor-binding protein 10. (368 aa)
	LOC107550085	Mothers against decapentaplegic homolog 4-like isoform X1. (571 aa)
	RNF165-2	RING finger protein 165-like isoform X1. (302 aa)
	ENSSGRP00000040388	annotation not available (390 aa)
	fbxl15	F-box and leucine-rich repeat protein 15. (311 aa)
	LOC107587642	Growth/differentiation factor 5-like. (499 aa)
	LOC107552890	Bone morphogenetic protein 2-like. (388 aa)
	LOC107584759	Bone morphogenetic protein receptor type-2-like. (1008 aa)
	LOC107555441	Bone morphogenetic protein receptor type-2-like isoform X1. (1018 aa)
	ENSSGRP00000029869	SMAD family member 4b. (484 aa)
	ENSSGRP00000028228	Ring finger protein 165b. (326 aa)
	LOC107551190	Growth/differentiation factor 6-A-like. (405 aa)
	LOC107564636	Cadherin 5, type 2, VE-cadherin. (770 aa)
	ENSSGRP00000023816	annotation not available (66 aa)
	LOC107548346	Dorsal-ventral patterning tolloid-like protein 1. (1022 aa)
	ENSSGRP00000022575	SMAD family member 4a. (499 aa)
	ENSSGRP00000022067	Bone morphogenetic protein 2-like. (332 aa)
	LOC107575291	Homeobox protein MSX-2-like. (224 aa)
	UBE2O	(E3-independent) E2 ubiquitin-conjugating enzyme. (1316 aa)
	ENSSGRP00000010396	SMAD family member 4b. (464 aa)
	LOC107559658	Mothers against decapentaplegic homolog 4 isoform X1. (550 aa)
	ENSSGRP00000007620	Serine/threonine-protein phosphatase 4 catalytic subunit B-like. (132 aa)
	LOC107566184	Beta-1,4-galactosyltransferase 5-like isoform X1. (418 aa)
	RNF165	RING finger protein 165-like isoform X1. (335 aa)

Your Current Organism:

Sinocyclocheilus grahami

NCBI taxonomy Id: 75366
Other names: S. grahami

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSSGRP00000010396	ENSSGRP00000022067	ENSSGRP00000010396	ENSSGRP00000022067	SMAD family member 4b.	Bone morphogenetic protein 2-like.	0.619
ENSSGRP00000010396	LOC107552890	ENSSGRP00000010396	ENSSGRP00000035716	SMAD family member 4b.	Bone morphogenetic protein 2-like.	0.619
ENSSGRP00000010396	LOC107555441	ENSSGRP00000010396	ENSSGRP00000030898	SMAD family member 4b.	Bone morphogenetic protein receptor type-2-like isoform X1.	0.634
ENSSGRP00000010396	LOC107584759	ENSSGRP00000010396	ENSSGRP00000031898	SMAD family member 4b.	Bone morphogenetic protein receptor type-2-like.	0.634
ENSSGRP00000010396	LOC107593012	ENSSGRP00000010396	ENSSGRP00000066173	SMAD family member 4b.	Bone morphogenetic protein receptor type-2-like.	0.634
ENSSGRP00000010396	LOC107593250	ENSSGRP00000010396	ENSSGRP00000108210	SMAD family member 4b.	Bone morphogenetic protein 2-like.	0.619
ENSSGRP00000010396	bmp2	ENSSGRP00000010396	ENSSGRP00000055548	SMAD family member 4b.	Bone morphogenetic protein 2.	0.619
ENSSGRP00000010396	bmpr2	ENSSGRP00000010396	ENSSGRP00000110397	SMAD family member 4b.	Bone morphogenetic protein receptor type-2 isoform X1.	0.752
ENSSGRP00000022067	ENSSGRP00000010396	ENSSGRP00000022067	ENSSGRP00000010396	Bone morphogenetic protein 2-like.	SMAD family member 4b.	0.619
ENSSGRP00000022067	ENSSGRP00000022575	ENSSGRP00000022067	ENSSGRP00000022575	Bone morphogenetic protein 2-like.	SMAD family member 4a.	0.619
ENSSGRP00000022067	ENSSGRP00000023816	ENSSGRP00000022067	ENSSGRP00000023816	Bone morphogenetic protein 2-like.	annotation not available	0.433
ENSSGRP00000022067	ENSSGRP00000029869	ENSSGRP00000022067	ENSSGRP00000029869	Bone morphogenetic protein 2-like.	SMAD family member 4b.	0.619
ENSSGRP00000022067	ENSSGRP00000076363	ENSSGRP00000022067	ENSSGRP00000076363	Bone morphogenetic protein 2-like.	Mothers against decapentaplegic homolog 4-like isoform X1.	0.619
ENSSGRP00000022067	ENSSGRP00000089762	ENSSGRP00000022067	ENSSGRP00000089762	Bone morphogenetic protein 2-like.	Si:dkey-222b8.1.	0.619
ENSSGRP00000022067	ENSSGRP00000098989	ENSSGRP00000022067	ENSSGRP00000098989	Bone morphogenetic protein 2-like.	Mothers against decapentaplegic homolog 4-like.	0.619
ENSSGRP00000022067	ENSSGRP00000104891	ENSSGRP00000022067	ENSSGRP00000104891	Bone morphogenetic protein 2-like.	Mothers against decapentaplegic homolog 4-like.	0.619
ENSSGRP00000022067	LOC107548346	ENSSGRP00000022067	ENSSGRP00000023623	Bone morphogenetic protein 2-like.	Dorsal-ventral patterning tolloid-like protein 1.	0.433
ENSSGRP00000022067	LOC107550085	ENSSGRP00000022067	ENSSGRP00000045624	Bone morphogenetic protein 2-like.	Mothers against decapentaplegic homolog 4-like isoform X1.	0.619
ENSSGRP00000022067	LOC107555441	ENSSGRP00000022067	ENSSGRP00000030898	Bone morphogenetic protein 2-like.	Bone morphogenetic protein receptor type-2-like isoform X1.	0.891
ENSSGRP00000022067	LOC107559658	ENSSGRP00000022067	ENSSGRP00000007947	Bone morphogenetic protein 2-like.	Mothers against decapentaplegic homolog 4 isoform X1.	0.619