(29 nodes) Negative regulation of fibroblast growth factor receptor signaling pathway network (Sinocyclocheilus grahami)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC107555763	Protein Churchill isoform X1. (130 aa)
	ENSSGRP00000074011	Extracellular sulfatase Sulf-2-like. (864 aa)
	ENSSGRP00000072798	Sulfatase 2b. (689 aa)
	ENSSGRP00000069199	LOW QUALITY PROTEIN: extracellular sulfatase Sulf-2-like. (875 aa)
	LOC107591231	Protein shisa-2-like. (294 aa)
	ENSSGRP00000047289	Tumor necrosis factor receptor superfamily member 16-like. (310 aa)
	LOC107561905	Glypican-1-like isoform X1. (554 aa)
	ENSSGRP00000039950	Interleukin-17 receptor D-like. (408 aa)
	inppl1	Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2. (1279 aa)
	LOC107574881	Protein sprouty homolog 1-like. (298 aa)
	LOC107597177	Interleukin 17 receptor D. (743 aa)
	LOC107586261	Transcription elongation factor SPT5-like isoform X1. (1080 aa)
	ENSSGRP00000022692	Inositol polyphosphate phosphatase-like 1a. (835 aa)
	ENSSGRP00000017277	PR domain zinc finger protein 14-like. (561 aa)
	ENSSGRP00000003188	Sulfatase 1. (1069 aa)
	SPRY4	Protein sprouty homolog 4-like. (311 aa)
	ENSSGRP00000108729	annotation not available (87 aa)
	ENSSGRP00000108375	PR domain zinc finger protein 14-like. (569 aa)
	LOC107557418	Interleukin-17 receptor D-like. (739 aa)
	ENSSGRP00000106475	Extracellular sulfatase Sulf-2-like. (740 aa)
	LOC107597543	Transcription elongation factor SPT5 isoform X1. (1077 aa)
	SPRY3	Protein sprouty homolog 3-like. (281 aa)
	ENSSGRP00000092304	Glypican-1-like. (511 aa)
	LOC107584966	Protein shisa-2-like. (294 aa)
	ENSSGRP00000088111	Glypican-1-like. (513 aa)
	LOC107581901	Protein sprouty homolog 4-like. (311 aa)
	LOC107556164	Protein Churchill-like. (116 aa)
	sulf1	Extracellular sulfatase Sulf-1 isoform X1. (1135 aa)
	LOC107588081	Glypican 1. (556 aa)

Your Current Organism:

Sinocyclocheilus grahami

NCBI taxonomy Id: 75366
Other names: S. grahami

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSSGRP00000022692	inppl1	ENSSGRP00000022692	ENSSGRP00000033332	Inositol polyphosphate phosphatase-like 1a.	Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2.	0.458
ENSSGRP00000039950	LOC107581901	ENSSGRP00000039950	ENSSGRP00000083316	Interleukin-17 receptor D-like.	Protein sprouty homolog 4-like.	0.493
ENSSGRP00000039950	SPRY4	ENSSGRP00000039950	ENSSGRP00000000643	Interleukin-17 receptor D-like.	Protein sprouty homolog 4-like.	0.493
ENSSGRP00000108729	LOC107574881	ENSSGRP00000108729	ENSSGRP00000026777	annotation not available	Protein sprouty homolog 1-like.	0.662
LOC107557418	LOC107581901	ENSSGRP00000107059	ENSSGRP00000083316	Interleukin-17 receptor D-like.	Protein sprouty homolog 4-like.	0.493
LOC107557418	SPRY4	ENSSGRP00000107059	ENSSGRP00000000643	Interleukin-17 receptor D-like.	Protein sprouty homolog 4-like.	0.493
LOC107574881	ENSSGRP00000108729	ENSSGRP00000026777	ENSSGRP00000108729	Protein sprouty homolog 1-like.	annotation not available	0.662
LOC107574881	LOC107581901	ENSSGRP00000026777	ENSSGRP00000083316	Protein sprouty homolog 1-like.	Protein sprouty homolog 4-like.	0.709
LOC107574881	SPRY3	ENSSGRP00000026777	ENSSGRP00000093298	Protein sprouty homolog 1-like.	Protein sprouty homolog 3-like.	0.676
LOC107574881	SPRY4	ENSSGRP00000026777	ENSSGRP00000000643	Protein sprouty homolog 1-like.	Protein sprouty homolog 4-like.	0.709
LOC107581901	ENSSGRP00000039950	ENSSGRP00000083316	ENSSGRP00000039950	Protein sprouty homolog 4-like.	Interleukin-17 receptor D-like.	0.493
LOC107581901	LOC107557418	ENSSGRP00000083316	ENSSGRP00000107059	Protein sprouty homolog 4-like.	Interleukin-17 receptor D-like.	0.493
LOC107581901	LOC107574881	ENSSGRP00000083316	ENSSGRP00000026777	Protein sprouty homolog 4-like.	Protein sprouty homolog 1-like.	0.709
LOC107581901	LOC107597177	ENSSGRP00000083316	ENSSGRP00000025166	Protein sprouty homolog 4-like.	Interleukin 17 receptor D.	0.493
LOC107597177	LOC107581901	ENSSGRP00000025166	ENSSGRP00000083316	Interleukin 17 receptor D.	Protein sprouty homolog 4-like.	0.493
LOC107597177	SPRY4	ENSSGRP00000025166	ENSSGRP00000000643	Interleukin 17 receptor D.	Protein sprouty homolog 4-like.	0.493
SPRY3	LOC107574881	ENSSGRP00000093298	ENSSGRP00000026777	Protein sprouty homolog 3-like.	Protein sprouty homolog 1-like.	0.676
SPRY4	ENSSGRP00000039950	ENSSGRP00000000643	ENSSGRP00000039950	Protein sprouty homolog 4-like.	Interleukin-17 receptor D-like.	0.493
SPRY4	LOC107557418	ENSSGRP00000000643	ENSSGRP00000107059	Protein sprouty homolog 4-like.	Interleukin-17 receptor D-like.	0.493
SPRY4	LOC107574881	ENSSGRP00000000643	ENSSGRP00000026777	Protein sprouty homolog 4-like.	Protein sprouty homolog 1-like.	0.709