(60 nodes) Negative regulation of synaptic transmission network (Sinocyclocheilus grahami)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ENSSGRP00000000793	Solute carrier family 24 (sodium/potassium/calcium exchanger), member 2. (227 aa)
	ENSSGRP00000110934	Parkin RBR E3 ubiquitin protein ligase. (455 aa)
	LOC107563106	Activity-dependent neuroprotector homeobox protein-like. (964 aa)
	ENSSGRP00000099876	85/88 kDa calcium-independent phospholipase A2-like. (159 aa)
	ENSSGRP00000099869	85/88 kDa calcium-independent phospholipase A2-like. (819 aa)
	LOC107556321	Ras-related protein Rap-1A-like. (185 aa)
	ENSSGRP00000095209	Sodium/potassium/calcium exchanger 2-like. (227 aa)
	LOC107557907	Ras-related protein Rap-1A-like. (185 aa)
	ENSSGRP00000091966	Abhydrolase domain containing 6a. (335 aa)
	ENSSGRP00000091518	D(3) dopamine receptor-like. (454 aa)
	LOC107568266	Serum response factor-like isoform X1. (285 aa)
	LOC107566714	Adiponectin-like. (276 aa)
	ENSSGRP00000079889	SH3 and multiple ankyrin repeat domains protein 2-like isoform X1. (1758 aa)
	ENSSGRP00000076063	RAP1B, member of RAS oncogene family. (126 aa)
	ENSSGRP00000074440	Leucine-rich repeat kinase 2. (1866 aa)
	ENSSGRP00000068949	Activity-dependent neuroprotector homeobox protein-like. (975 aa)
	ENSSGRP00000068816	Leucine-rich repeat serine/threonine-protein kinase 2-like. (2360 aa)
	LOC107594183	Delphilin-like isoform X1. (1137 aa)
	LOC107558359	tenascin-R-like. (1323 aa)
	prkn	E3 ubiquitin-protein ligase parkin. (438 aa)
	ENSSGRP00000062565	SH3 and multiple ankyrin repeat domains protein 2-like. (1794 aa)
	ENSSGRP00000060320	Neurofibromin-like isoform X1. (2497 aa)
	ENSSGRP00000059112	Delphilin-like. (85 aa)
	ENSSGRP00000059111	Glutamate receptor, ionotropic, delta 2 (Grid2) interacting protein, a. (896 aa)
	LOC107583763	Solute carrier family 24 (sodium/potassium/calcium exchanger), member 1. (719 aa)
	LOC107602675	85/88 kDa calcium-independent phospholipase A2-like. (819 aa)
	ENSSGRP00000055520	LOW QUALITY PROTEIN: neurofibromin-like. (2706 aa)
	ENSSGRP00000055176	Serum response factor-like. (238 aa)
	rap1b	RAP1B, member of RAS oncogene family. (185 aa)
	ENSSGRP00000049360	annotation not available (98 aa)
	LOC107591280	D(3) dopamine receptor-like. (454 aa)
	ENSSGRP00000047641	Neurofibromin-like isoform X1. (2280 aa)
	LOC107560889	Abhydrolase domain-containing protein 6. (339 aa)
	PRRT1	Proline-rich transmembrane protein 1-like. (100 aa)
	LOC107551382	Serum response factor-like. (524 aa)
	ENSSGRP00000043434	FMRP translational regulator 1. (595 aa)
	LOC107560426	Ras-related protein Rap-1A-like. (185 aa)
	ENSSGRP00000043014	SH3 and multiple ankyrin repeat domains protein 2-like. (1339 aa)
	ENSSGRP00000041380	Abhydrolase domain containing 6b. (297 aa)
	ENSSGRP00000039591	Glutamate receptor, ionotropic, delta 2 (Grid2) interacting protein, a. (928 aa)
	ENSSGRP00000038885	Neurofibromin-like. (2731 aa)
	ENSSGRP00000031776	Si:ch73-71c20.5. (168 aa)
	ENSSGRP00000031730	Paroxysmal nonkinesiogenic dyskinesia protein. (397 aa)
	ENSSGRP00000031551	Activity-dependent neuroprotector homeobox b. (948 aa)
	ENSSGRP00000031221	Paroxysmal nonkinesiogenic dyskinesia protein. (345 aa)
	ENSSGRP00000028537	annotation not available (349 aa)
	ENSSGRP00000028039	Sodium/potassium/calcium exchanger 2-like. (320 aa)
	LOC107594522	Ras-related protein Rap-1A. (185 aa)
	ENSSGRP00000023709	annotation not available (432 aa)
	ENSSGRP00000023251	annotation not available (93 aa)
	ENSSGRP00000018198	Serum response factor-like. (238 aa)
	ENSSGRP00000016613	Sodium/potassium/calcium exchanger 2-like. (923 aa)
	ENSSGRP00000016611	annotation not available (393 aa)
	tnr	Tenascin-R isoform X1. (1364 aa)
	ENSSGRP00000010987	FMRP translational regulator 1. (568 aa)
	ENSSGRP00000009419	Glutamate receptor, ionotropic, delta 2 (Grid2) interacting protein, b. (1141 aa)
	LOC107577312	Activity-dependent neuroprotector homeobox protein-like. (617 aa)
	ENSSGRP00000003260	SH3 and multiple ankyrin repeat domains protein 2-like. (957 aa)
	LOC107596980	Solute carrier family 24 (sodium/potassium/calcium exchanger), member 1. (719 aa)
	LOC107564988	Complexin-1-like. (134 aa)

Your Current Organism:

Sinocyclocheilus grahami

NCBI taxonomy Id: 75366
Other names: S. grahami

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSSGRP00000038885	ENSSGRP00000076063	ENSSGRP00000038885	ENSSGRP00000076063	Neurofibromin-like.	RAP1B, member of RAS oncogene family.	0.565
ENSSGRP00000038885	LOC107556321	ENSSGRP00000038885	ENSSGRP00000096911	Neurofibromin-like.	Ras-related protein Rap-1A-like.	0.565
ENSSGRP00000038885	LOC107557907	ENSSGRP00000038885	ENSSGRP00000092053	Neurofibromin-like.	Ras-related protein Rap-1A-like.	0.565
ENSSGRP00000038885	LOC107560426	ENSSGRP00000038885	ENSSGRP00000043065	Neurofibromin-like.	Ras-related protein Rap-1A-like.	0.565
ENSSGRP00000038885	LOC107594522	ENSSGRP00000038885	ENSSGRP00000027032	Neurofibromin-like.	Ras-related protein Rap-1A.	0.565
ENSSGRP00000038885	rap1b	ENSSGRP00000038885	ENSSGRP00000050062	Neurofibromin-like.	RAP1B, member of RAS oncogene family.	0.565
ENSSGRP00000047641	ENSSGRP00000076063	ENSSGRP00000047641	ENSSGRP00000076063	Neurofibromin-like isoform X1.	RAP1B, member of RAS oncogene family.	0.565
ENSSGRP00000047641	LOC107556321	ENSSGRP00000047641	ENSSGRP00000096911	Neurofibromin-like isoform X1.	Ras-related protein Rap-1A-like.	0.565
ENSSGRP00000047641	LOC107557907	ENSSGRP00000047641	ENSSGRP00000092053	Neurofibromin-like isoform X1.	Ras-related protein Rap-1A-like.	0.565
ENSSGRP00000047641	LOC107560426	ENSSGRP00000047641	ENSSGRP00000043065	Neurofibromin-like isoform X1.	Ras-related protein Rap-1A-like.	0.565
ENSSGRP00000047641	LOC107594522	ENSSGRP00000047641	ENSSGRP00000027032	Neurofibromin-like isoform X1.	Ras-related protein Rap-1A.	0.565
ENSSGRP00000047641	rap1b	ENSSGRP00000047641	ENSSGRP00000050062	Neurofibromin-like isoform X1.	RAP1B, member of RAS oncogene family.	0.565
ENSSGRP00000055520	ENSSGRP00000076063	ENSSGRP00000055520	ENSSGRP00000076063	LOW QUALITY PROTEIN: neurofibromin-like.	RAP1B, member of RAS oncogene family.	0.565
ENSSGRP00000055520	LOC107556321	ENSSGRP00000055520	ENSSGRP00000096911	LOW QUALITY PROTEIN: neurofibromin-like.	Ras-related protein Rap-1A-like.	0.565
ENSSGRP00000055520	LOC107557907	ENSSGRP00000055520	ENSSGRP00000092053	LOW QUALITY PROTEIN: neurofibromin-like.	Ras-related protein Rap-1A-like.	0.565
ENSSGRP00000055520	LOC107560426	ENSSGRP00000055520	ENSSGRP00000043065	LOW QUALITY PROTEIN: neurofibromin-like.	Ras-related protein Rap-1A-like.	0.565
ENSSGRP00000055520	LOC107594522	ENSSGRP00000055520	ENSSGRP00000027032	LOW QUALITY PROTEIN: neurofibromin-like.	Ras-related protein Rap-1A.	0.565
ENSSGRP00000055520	rap1b	ENSSGRP00000055520	ENSSGRP00000050062	LOW QUALITY PROTEIN: neurofibromin-like.	RAP1B, member of RAS oncogene family.	0.565
ENSSGRP00000060320	ENSSGRP00000076063	ENSSGRP00000060320	ENSSGRP00000076063	Neurofibromin-like isoform X1.	RAP1B, member of RAS oncogene family.	0.565
ENSSGRP00000060320	LOC107556321	ENSSGRP00000060320	ENSSGRP00000096911	Neurofibromin-like isoform X1.	Ras-related protein Rap-1A-like.	0.565