(36 nodes) I-SMAD binding network (Sinocyclocheilus grahami)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC107583760	Mothers against decapentaplegic homolog 3-like. (453 aa)
	LOC107550085	Mothers against decapentaplegic homolog 4-like isoform X1. (571 aa)
	ENSSGRP00000038606	annotation not available (251 aa)
	SMAD9	Mothers against decapentaplegic homolog 9-like isoform X1. (434 aa)
	ENSSGRP00000039728	annotation not available (966 aa)
	smad3	Mothers against decapentaplegic homolog 3. (425 aa)
	smad6	Mothers against decapentaplegic homolog 6. (450 aa)
	LOC107559658	Mothers against decapentaplegic homolog 4 isoform X1. (550 aa)
	ENSSGRP00000010396	SMAD family member 4b. (464 aa)
	ENSSGRP00000013976	SMAD family member 1. (442 aa)
	ENSSGRP00000022575	SMAD family member 4a. (499 aa)
	ENSSGRP00000029082	Axin-1-like isoform X1. (165 aa)
	ENSSGRP00000029083	annotation not available (154 aa)
	ENSSGRP00000070226	Mothers against decapentaplegic homolog 6-like isoform X1. (454 aa)
	ENSSGRP00000076363	Mothers against decapentaplegic homolog 4-like isoform X1. (573 aa)
	ENSSGRP00000089762	Si:dkey-222b8.1. (527 aa)
	LOC107585655	Mothers against decapentaplegic homolog 7-like. (371 aa)
	LOC107568923	Axin 1. (830 aa)
	LOC107553101	Mothers against decapentaplegic homolog 3. (439 aa)
	LOC107555085	Axin-2-like. (813 aa)
	ENSSGRP00000063151	Integrator complex subunit 8-like. (868 aa)
	ENSSGRP00000062617	Mothers against decapentaplegic homolog 1. (458 aa)
	SMAD9-2	SMAD family member 9. (468 aa)
	LOC107563595	Mothers against decapentaplegic homolog 5 isoform X1. (464 aa)
	ENSSGRP00000098989	Mothers against decapentaplegic homolog 4-like. (169 aa)
	ENSSGRP00000104891	Mothers against decapentaplegic homolog 4-like. (571 aa)
	ENSSGRP00000108174	Mothers against decapentaplegic homolog 3-like. (68 aa)
	LOC107596967	Mothers against decapentaplegic homolog 6-like. (488 aa)
	ENSSGRP00000036219	Mothers against decapentaplegic homolog 1-like. (181 aa)
	ENSSGRP00000036217	annotation not available (113 aa)
	smad2	Mothers against decapentaplegic homolog 2. (468 aa)
	LOC107556609	Axin 2. (813 aa)
	ENSSGRP00000029869	SMAD family member 4b. (484 aa)
	Smad7	Mothers against decapentaplegic homolog 7. (182 aa)
	ENSSGRP00000038959	Axin-1-like. (273 aa)
	LOC107583766	Mothers against decapentaplegic homolog 6-like. (487 aa)

Your Current Organism:

Sinocyclocheilus grahami

NCBI taxonomy Id: 75366
Other names: S. grahami

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSSGRP00000010396	ENSSGRP00000013976	ENSSGRP00000010396	ENSSGRP00000013976	SMAD family member 4b.	SMAD family member 1.	0.822
ENSSGRP00000010396	ENSSGRP00000036217	ENSSGRP00000010396	ENSSGRP00000036217	SMAD family member 4b.	annotation not available	0.781
ENSSGRP00000010396	ENSSGRP00000036219	ENSSGRP00000010396	ENSSGRP00000036219	SMAD family member 4b.	Mothers against decapentaplegic homolog 1-like.	0.781
ENSSGRP00000010396	ENSSGRP00000038606	ENSSGRP00000010396	ENSSGRP00000038606	SMAD family member 4b.	annotation not available	0.721
ENSSGRP00000010396	ENSSGRP00000039728	ENSSGRP00000010396	ENSSGRP00000039728	SMAD family member 4b.	annotation not available	0.721
ENSSGRP00000010396	ENSSGRP00000062617	ENSSGRP00000010396	ENSSGRP00000062617	SMAD family member 4b.	Mothers against decapentaplegic homolog 1.	0.822
ENSSGRP00000010396	ENSSGRP00000063151	ENSSGRP00000010396	ENSSGRP00000063151	SMAD family member 4b.	Integrator complex subunit 8-like.	0.721
ENSSGRP00000010396	ENSSGRP00000070226	ENSSGRP00000010396	ENSSGRP00000070226	SMAD family member 4b.	Mothers against decapentaplegic homolog 6-like isoform X1.	0.586
ENSSGRP00000010396	ENSSGRP00000108174	ENSSGRP00000010396	ENSSGRP00000108174	SMAD family member 4b.	Mothers against decapentaplegic homolog 3-like.	0.813
ENSSGRP00000010396	LOC107553101	ENSSGRP00000010396	ENSSGRP00000070223	SMAD family member 4b.	Mothers against decapentaplegic homolog 3.	0.853
ENSSGRP00000010396	LOC107563595	ENSSGRP00000010396	ENSSGRP00000051610	SMAD family member 4b.	Mothers against decapentaplegic homolog 5 isoform X1.	0.781
ENSSGRP00000010396	LOC107583760	ENSSGRP00000010396	ENSSGRP00000049287	SMAD family member 4b.	Mothers against decapentaplegic homolog 3-like.	0.813
ENSSGRP00000010396	LOC107583766	ENSSGRP00000010396	ENSSGRP00000049337	SMAD family member 4b.	Mothers against decapentaplegic homolog 6-like.	0.580
ENSSGRP00000010396	LOC107585655	ENSSGRP00000010396	ENSSGRP00000094207	SMAD family member 4b.	Mothers against decapentaplegic homolog 7-like.	0.454
ENSSGRP00000010396	LOC107596967	ENSSGRP00000010396	ENSSGRP00000108175	SMAD family member 4b.	Mothers against decapentaplegic homolog 6-like.	0.581
ENSSGRP00000010396	SMAD9	ENSSGRP00000010396	ENSSGRP00000044683	SMAD family member 4b.	Mothers against decapentaplegic homolog 9-like isoform X1.	0.799
ENSSGRP00000010396	SMAD9-2	ENSSGRP00000010396	ENSSGRP00000058417	SMAD family member 4b.	SMAD family member 9.	0.799
ENSSGRP00000010396	Smad7	ENSSGRP00000010396	ENSSGRP00000050201	SMAD family member 4b.	Mothers against decapentaplegic homolog 7.	0.454
ENSSGRP00000010396	smad2	ENSSGRP00000010396	ENSSGRP00000033834	SMAD family member 4b.	Mothers against decapentaplegic homolog 2.	0.904
ENSSGRP00000010396	smad3	ENSSGRP00000010396	ENSSGRP00000003942	SMAD family member 4b.	Mothers against decapentaplegic homolog 3.	0.853