(14 nodes) interleukin-23 complex network (Sinocyclocheilus grahami)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC107586675	Interleukin-17A-like. (140 aa)
	LOC107570759	Interleukin-12 subunit beta-like. (311 aa)
	LOC107602578	Interleukin-12 subunit beta-like. (325 aa)
	ENSSGRP00000041855	Interleukin-12 subunit beta-like. (335 aa)
	LOC107560122	Interleukin-12 subunit beta-like. (301 aa)
	LOC107589678	Interleukin-17F-like. (158 aa)
	LOC107589636	Interleukin-17F-like. (142 aa)
	LOC107601021	Interleukin-12 subunit beta-like. (298 aa)
	ENSSGRP00000067602	Interleukin-17F-like. (162 aa)
	LOC107597382	Interleukin-17D-like. (203 aa)
	LOC107594820	Interleukin-6 receptor subunit alpha-like isoform X1. (621 aa)
	ENSSGRP00000082122	Interleukin-17F-like. (150 aa)
	LOC107588798	Interleukin-12 subunit beta-like. (313 aa)
	LOC107586610	Interleukin-17F-like. (159 aa)

Your Current Organism:

Sinocyclocheilus grahami

NCBI taxonomy Id: 75366
Other names: S. grahami

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structured XML interaction data, according to the 'PSI-MI' data standard

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node degree of proteins in your network (given the current score cut-off)

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a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSSGRP00000041855	LOC107588798	ENSSGRP00000041855	ENSSGRP00000089621	Interleukin-12 subunit beta-like.	Interleukin-12 subunit beta-like.	0.908
ENSSGRP00000041855	LOC107602578	ENSSGRP00000041855	ENSSGRP00000038900	Interleukin-12 subunit beta-like.	Interleukin-12 subunit beta-like.	0.901
LOC107586610	LOC107586675	ENSSGRP00000100225	ENSSGRP00000100226	Interleukin-17F-like.	Interleukin-17A-like.	0.447
LOC107586675	LOC107586610	ENSSGRP00000100226	ENSSGRP00000100225	Interleukin-17A-like.	Interleukin-17F-like.	0.447
LOC107586675	LOC107589678	ENSSGRP00000100226	ENSSGRP00000062119	Interleukin-17A-like.	Interleukin-17F-like.	0.447
LOC107586675	LOC107597382	ENSSGRP00000100226	ENSSGRP00000072399	Interleukin-17A-like.	Interleukin-17D-like.	0.447
LOC107588798	ENSSGRP00000041855	ENSSGRP00000089621	ENSSGRP00000041855	Interleukin-12 subunit beta-like.	Interleukin-12 subunit beta-like.	0.908
LOC107588798	LOC107602578	ENSSGRP00000089621	ENSSGRP00000038900	Interleukin-12 subunit beta-like.	Interleukin-12 subunit beta-like.	0.908
LOC107589678	LOC107586675	ENSSGRP00000062119	ENSSGRP00000100226	Interleukin-17F-like.	Interleukin-17A-like.	0.447
LOC107597382	LOC107586675	ENSSGRP00000072399	ENSSGRP00000100226	Interleukin-17D-like.	Interleukin-17A-like.	0.447
LOC107602578	ENSSGRP00000041855	ENSSGRP00000038900	ENSSGRP00000041855	Interleukin-12 subunit beta-like.	Interleukin-12 subunit beta-like.	0.901
LOC107602578	LOC107588798	ENSSGRP00000038900	ENSSGRP00000089621	Interleukin-12 subunit beta-like.	Interleukin-12 subunit beta-like.	0.908