STRINGSTRING
F6ZGX7_CIOIN F6ZGX7_CIOIN hvcn1 hvcn1 LOC100183881 LOC100183881 F6YSG2_CIOIN F6YSG2_CIOIN F6SLD6_CIOIN F6SLD6_CIOIN F6SJR0_CIOIN F6SJR0_CIOIN mef2 mef2 F6TGA3_CIOIN F6TGA3_CIOIN F6TG38_CIOIN F6TG38_CIOIN F7AK54_CIOIN F7AK54_CIOIN H2XJT4_CIOIN H2XJT4_CIOIN LOC100183075 LOC100183075 H2XKK7_CIOIN H2XKK7_CIOIN H2XLJ9_CIOIN H2XLJ9_CIOIN LOC100182592 LOC100182592 LOC100178517 LOC100178517 zf(an1)-2 zf(an1)-2 H2XSF3_CIOIN H2XSF3_CIOIN H2XT29_CIOIN H2XT29_CIOIN LOC100181245 LOC100181245 LOC100175802 LOC100175802 LOC101243377 LOC101243377 H2XUG5_CIOIN H2XUG5_CIOIN H2XXS6_CIOIN H2XXS6_CIOIN H2XXW3_CIOIN H2XXW3_CIOIN H2XXZ3_CIOIN H2XXZ3_CIOIN H2XY36_CIOIN H2XY36_CIOIN H2XYB3_CIOIN H2XYB3_CIOIN H2XZE7_CIOIN H2XZE7_CIOIN H2XZT3_CIOIN H2XZT3_CIOIN H2XZZ6_CIOIN H2XZZ6_CIOIN H2Y0A0_CIOIN H2Y0A0_CIOIN LOC100179361 LOC100179361 H2Y1K8_CIOIN H2Y1K8_CIOIN H2Y2V4_CIOIN H2Y2V4_CIOIN F6SYE0_CIOIN F6SYE0_CIOIN LOC100183684 LOC100183684 F6YCG7_CIOIN F6YCG7_CIOIN F6Q3Y2_CIOIN F6Q3Y2_CIOIN LOC100180226 LOC100180226 LOC100176290 LOC100176290 F6U1C4_CIOIN F6U1C4_CIOIN LOC100184311 LOC100184311 LOC100177697 LOC100177697 LOC100176626 LOC100176626 F6T8Y3_CIOIN F6T8Y3_CIOIN F6WJF4_CIOIN F6WJF4_CIOIN gsk gsk F6VXA3_CIOIN F6VXA3_CIOIN LOC100182857 LOC100182857 F6X4B8_CIOIN F6X4B8_CIOIN F6W6K0_CIOIN F6W6K0_CIOIN LOC100175701 LOC100175701 F6ZYB8_CIOIN F6ZYB8_CIOIN per-like per-like F6PL57_CIOIN F6PL57_CIOIN F6PHN1_CIOIN F6PHN1_CIOIN LOC100184788 LOC100184788 LOC100186563 LOC100186563 F6TBE2_CIOIN F6TBE2_CIOIN F6U9V6_CIOIN F6U9V6_CIOIN F6U899_CIOIN F6U899_CIOIN F6XH38_CIOIN F6XH38_CIOIN F6ZM08_CIOIN F6ZM08_CIOIN F6Z370_CIOIN F6Z370_CIOIN F6YH93_CIOIN F6YH93_CIOIN F6YFV6_CIOIN F6YFV6_CIOIN LOC100182293 LOC100182293 F6V6N1_CIOIN F6V6N1_CIOIN F7BN93_CIOIN F7BN93_CIOIN LOC100178767 LOC100178767 creb/atf-c creb/atf-c F6TXZ0_CIOIN F6TXZ0_CIOIN LOC100176033 LOC100176033 F7B7H5_CIOIN F7B7H5_CIOIN LOC100184540 LOC100184540 F6UYT5_CIOIN F6UYT5_CIOIN F6RDK2_CIOIN F6RDK2_CIOIN F6RJ12_CIOIN F6RJ12_CIOIN Zf(c2h2)-141 Zf(c2h2)-141 LOC100186228 LOC100186228 F6ZLD5_CIOIN F6ZLD5_CIOIN F6SPF7_CIOIN F6SPF7_CIOIN F6TL19_CIOIN F6TL19_CIOIN Erk5 Erk5 LOC100179207 LOC100179207 F6ZHS2_CIOIN F6ZHS2_CIOIN LOC100180646 LOC100180646 F6WBE9_CIOIN F6WBE9_CIOIN ci-glyr ci-glyr F6Z5E6_CIOIN F6Z5E6_CIOIN F6Q9D5_CIOIN F6Q9D5_CIOIN F6R3M6_CIOIN F6R3M6_CIOIN LOC100181869 LOC100181869 zf(ring)-55 zf(ring)-55 F6Z833_CIOIN F6Z833_CIOIN F6ZJ88_CIOIN F6ZJ88_CIOIN F6VXC2_CIOIN F6VXC2_CIOIN F6XVY9_CIOIN F6XVY9_CIOIN F6U7R9_CIOIN F6U7R9_CIOIN LOC100185622 LOC100185622 F6SWY4_CIOIN F6SWY4_CIOIN LOC100187157 LOC100187157 erk1/2 erk1/2 F6WVX7_CIOIN F6WVX7_CIOIN Syt1 Syt1 LOC100183113 LOC100183113 F6ZFJ9_CIOIN F6ZFJ9_CIOIN F6ZGZ0_CIOIN F6ZGZ0_CIOIN
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
F6ZGX7_CIOINUncharacterized protein. (629 aa)
hvcn1Voltage-gated hydrogen channel 1; Mediates the voltage-dependent proton permeability of excitable membranes. Forms a proton-selective channel through which protons may pass in accordance with their electrochemical gradient (By similarity). (342 aa)
LOC100183881Uncharacterized protein. (546 aa)
F6YSG2_CIOINRWD domain-containing protein. (260 aa)
F6SLD6_CIOINDeacetylase sirtuin-type domain-containing protein. (737 aa)
F6SJR0_CIOINUncharacterized protein. (187 aa)
mef2MADS-box domain-containing protein. (439 aa)
F6TGA3_CIOINUncharacterized protein. (561 aa)
F6TG38_CIOINUncharacterized protein. (582 aa)
F7AK54_CIOINGlutaredoxin domain-containing protein. (100 aa)
H2XJT4_CIOINPHD-type domain-containing protein. (508 aa)
LOC100183075Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (215 aa)
H2XKK7_CIOINUncharacterized protein. (436 aa)
H2XLJ9_CIOINUncharacterized protein. (177 aa)
LOC100182592BCL2/adenovirus E1B 19 kDa protein-interacting protein 3-like. (202 aa)
LOC100178517Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (142 aa)
zf(an1)-2AN1-type zinc finger protein 1. (260 aa)
H2XSF3_CIOINUncharacterized protein. (5075 aa)
H2XT29_CIOINNcstrn_small domain-containing protein. (568 aa)
LOC100181245Glutaredoxin-like. (107 aa)
LOC100175802Peroxiredoxin-like. (235 aa)
LOC101243377Migration and invasion enhancer 1. (76 aa)
H2XUG5_CIOINUncharacterized protein. (826 aa)
H2XXS6_CIOINMoCF_biosynth domain-containing protein. (151 aa)
H2XXW3_CIOINUncharacterized protein. (851 aa)
H2XXZ3_CIOINUncharacterized protein. (870 aa)
H2XY36_CIOINPeptidase C83 domain-containing protein. (126 aa)
H2XYB3_CIOINUncharacterized protein. (810 aa)
H2XZE7_CIOINGlutaredoxin domain-containing protein. (133 aa)
H2XZT3_CIOINUncharacterized protein. (121 aa)
H2XZZ6_CIOINProtein kinase domain-containing protein. (416 aa)
H2Y0A0_CIOINSuperoxide dismutase [Cu-Zn]; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the Cu-Zn superoxide dismutase family. (156 aa)
LOC100179361Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. (1269 aa)
H2Y1K8_CIOINCopine domain-containing protein. (257 aa)
H2Y2V4_CIOINProtein kinase domain-containing protein. (209 aa)
F6SYE0_CIOINProtein kinase domain-containing protein. (216 aa)
LOC100183684Tyrosine aminotransferase; Transaminase involved in tyrosine breakdown. Converts tyrosine to p-hydroxyphenylpyruvate. (415 aa)
F6YCG7_CIOINAdenylate cyclase type 6; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1086 aa)
F6Q3Y2_CIOINC2H2-type domain-containing protein. (458 aa)
LOC100180226Alpha-1,3/1,6-mannosyltransferase ALG2. (437 aa)
LOC100176290Uncharacterized protein LOC100176290 isoform X4. (787 aa)
F6U1C4_CIOINUncharacterized protein. (318 aa)
LOC100184311Peflin-like. (184 aa)
LOC100177697Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (236 aa)
LOC100176626Sorcin-like. (181 aa)
F6T8Y3_CIOINUncharacterized protein. (344 aa)
F6WJF4_CIOINC2 domain-containing protein. (464 aa)
gskGlycogen synthase kinase Alpha/beta. (407 aa)
F6VXA3_CIOINSolute carrier family 40 protein; May be involved in iron transport and iron homeostasis. Belongs to the ferroportin (FP) (TC 2.A.100) family. SLC40A subfamily. (533 aa)
LOC100182857Synaptotagmin-5-like isoform X1. (447 aa)
F6X4B8_CIOINUncharacterized protein; Belongs to the mitochondrial carrier (TC 2.A.29) family. (600 aa)
F6W6K0_CIOINUncharacterized protein. (534 aa)
LOC100175701Uncharacterized protein. (567 aa)
F6ZYB8_CIOINSphingomyelin phosphodiesterase; Converts sphingomyelin to ceramide. Belongs to the acid sphingomyelinase family. (599 aa)
per-likePeroxiredoxin-like. (197 aa)
F6PL57_CIOINUncharacterized protein. (1087 aa)
F6PHN1_CIOINProtein kinase domain-containing protein. (1026 aa)
LOC100184788Non-specific serine/threonine protein kinase. (554 aa)
LOC100186563Sphingomyelin phosphodiesterase; Converts sphingomyelin to ceramide. Belongs to the acid sphingomyelinase family. (599 aa)
F6TBE2_CIOINUncharacterized protein. (444 aa)
F6U9V6_CIOINUBA domain-containing protein. (204 aa)
F6U899_CIOINDJ-1_PfpI domain-containing protein. (187 aa)
F6XH38_CIOINUncharacterized protein. (637 aa)
F6ZM08_CIOINUncharacterized protein. (782 aa)
F6Z370_CIOINUncharacterized protein. (372 aa)
F6YH93_CIOINUncharacterized protein. (1111 aa)
F6YFV6_CIOINHMA domain-containing protein. (275 aa)
LOC100182293Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family. (217 aa)
F6V6N1_CIOINUncharacterized protein. (807 aa)
F7BN93_CIOINPfkB domain-containing protein. (311 aa)
LOC100178767Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (587 aa)
creb/atf-cTranscription factor Ci-CREB/ATF-c isoform X1. (298 aa)
F6TXZ0_CIOINANK_REP_REGION domain-containing protein; Belongs to the transient receptor (TC 1.A.4) family. (1047 aa)
LOC100176033KH type-2 domain-containing protein; Belongs to the universal ribosomal protein uS3 family. (263 aa)
F7B7H5_CIOINCatalase; Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide. (521 aa)
LOC100184540Death domain-associated protein 6-like isoform X1. (234 aa)
F6UYT5_CIOINAC_N domain-containing protein. (314 aa)
F6RDK2_CIOINUncharacterized protein. (1760 aa)
F6RJ12_CIOINKinase; Belongs to the inositol phosphokinase (IPK) family. (295 aa)
Zf(c2h2)-141Uncharacterized protein. (578 aa)
LOC100186228Peptidase C83 domain-containing protein. (333 aa)
F6ZLD5_CIOINProtein kinase domain-containing protein. (164 aa)
F6SPF7_CIOINUncharacterized protein. (438 aa)
F6TL19_CIOINENDO3c domain-containing protein. (364 aa)
Erk5Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (820 aa)
LOC100179207uroporphyrinogen-III synthase-like. (251 aa)
F6ZHS2_CIOINUncharacterized protein. (484 aa)
LOC100180646Glutathione synthetase. (448 aa)
F6WBE9_CIOINGSH_synthase domain-containing protein. (207 aa)
ci-glyrGlycine receptor precursor; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (491 aa)
F6Z5E6_CIOINLon protease homolog, mitochondrial; ATP-dependent serine protease that mediates the selective degradation of misfolded, unassembled or oxidatively damaged polypeptides as well as certain short-lived regulatory proteins in the mitochondrial matrix. May also have a chaperone function in the assembly of inner membrane protein complexes. Participates in the regulation of mitochondrial gene expression and in the maintenance of the integrity of the mitochondrial genome. Binds to mitochondrial DNA in a site-specific manner; Belongs to the peptidase S16 family. ECO:0000256|PROSITE-. (844 aa)
F6Q9D5_CIOINMetallophos domain-containing protein. (435 aa)
F6R3M6_CIOINUncharacterized protein. (741 aa)
LOC100181869Hcy-binding domain-containing protein. (191 aa)
zf(ring)-55Zinc finger protein. (323 aa)
F6Z833_CIOINUncharacterized protein. (250 aa)
F6ZJ88_CIOINUncharacterized protein. (341 aa)
F6VXC2_CIOINProtein kinase domain-containing protein; Belongs to the protein kinase superfamily. (262 aa)
F6XVY9_CIOINHECT domain-containing protein. (862 aa)
F6U7R9_CIOINUncharacterized protein. (1408 aa)
LOC100185622Programmed cell death protein 6-like. (208 aa)
F6SWY4_CIOINUncharacterized protein. (393 aa)
LOC100187157Uncharacterized protein; Belongs to the AAA ATPase family. (811 aa)
erk1/2Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (350 aa)
F6WVX7_CIOINANK_REP_REGION domain-containing protein. (674 aa)
Syt1Uncharacterized protein. (328 aa)
LOC100183113Uncharacterized protein. (533 aa)
F6ZFJ9_CIOINAlpha-type protein kinase domain-containing protein. (678 aa)
F6ZGZ0_CIOINUncharacterized protein. (615 aa)
Your Current Organism:
Ciona intestinalis
NCBI taxonomy Id: 7719
Other names: Ascidia intestinalis, C. intestinalis, sea vase, vase tunicate, yellow sea squirt
Server load: low (26%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.