(28 nodes) Negative regulation of transforming growth factor beta receptor signaling pathway network (Branchiostoma floridae)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	C3ZCW2_BRAFL	Uncharacterized protein. (982 aa)
	C3YKX2_BRAFL	Deacetylase sirtuin-type domain-containing protein. (312 aa)
	C3YL76_BRAFL	Uncharacterized protein. (297 aa)
	C3YL77_BRAFL	Uncharacterized protein. (230 aa)
	C3YQ30_BRAFL	Peptidyl-prolyl cis-trans isomerase. (151 aa)
	C3YUE5_BRAFL	Uncharacterized protein. (994 aa)
	C3Z7U5_BRAFL	Uncharacterized protein. (427 aa)
	C3Z7U6_BRAFL	HECT domain-containing protein. (341 aa)
	C3Z851_BRAFL	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (135 aa)
	C3ZB87_BRAFL	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (138 aa)
	C3ZB88_BRAFL	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (138 aa)
	C3ZBB2_BRAFL	Uncharacterized protein. (200 aa)
	C3YDK5_BRAFL	Ig-like domain-containing protein. (831 aa)
	C3ZFE5_BRAFL	PIN_11 domain-containing protein. (1580 aa)
	C3ZFF5_BRAFL	Mothers against decapentaplegic homolog. (854 aa)
	C3ZFZ9_BRAFL	Uncharacterized protein. (1402 aa)
	C3ZNQ4_BRAFL	PIN_11 domain-containing protein. (371 aa)
	C3ZP06_BRAFL	Uncharacterized protein. (293 aa)
	C3ZQP5_BRAFL	Disintegrin domain-containing protein. (277 aa)
	C3ZQP6_BRAFL	Peptidase M12B domain-containing protein. (99 aa)
	C3ZTF9_BRAFL	Uncharacterized protein; Belongs to the heat shock protein 70 family. (665 aa)
	C3ZVQ9_BRAFL	c-SKI_SMAD_bind domain-containing protein. (297 aa)
	C3Y9D4_BRAFL	Uncharacterized protein. (550 aa)
	C3Y795_BRAFL	WD_REPEATS_REGION domain-containing protein. (323 aa)
	C3XYA9_BRAFL	Uncharacterized protein. (440 aa)
	C3XU69_BRAFL	Uncharacterized protein. (1299 aa)
	C3XQQ3_BRAFL	MSC domain-containing protein. (153 aa)
	C3XQ29_BRAFL	PH domain-containing protein. (722 aa)

Your Current Organism:

Branchiostoma floridae

NCBI taxonomy Id: 7739
Other names: Amphioxus floridae, B. floridae, Florida lancelet

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
C3XQQ3_BRAFL	C3ZFF5_BRAFL	C3XQQ3	C3ZFF5	MSC domain-containing protein.	Mothers against decapentaplegic homolog.	0.432
C3Y795_BRAFL	C3ZFF5_BRAFL	C3Y795	C3ZFF5	WD_REPEATS_REGION domain-containing protein.	Mothers against decapentaplegic homolog.	0.707
C3Z7U5_BRAFL	C3Z7U6_BRAFL	C3Z7U5	C3Z7U6	Uncharacterized protein.	HECT domain-containing protein.	0.900
C3Z7U5_BRAFL	C3ZFF5_BRAFL	C3Z7U5	C3ZFF5	Uncharacterized protein.	Mothers against decapentaplegic homolog.	0.959
C3Z7U6_BRAFL	C3Z7U5_BRAFL	C3Z7U6	C3Z7U5	HECT domain-containing protein.	Uncharacterized protein.	0.900
C3Z7U6_BRAFL	C3ZFF5_BRAFL	C3Z7U6	C3ZFF5	HECT domain-containing protein.	Mothers against decapentaplegic homolog.	0.995
C3Z851_BRAFL	C3ZB87_BRAFL	C3Z851	C3ZB87	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	0.904
C3Z851_BRAFL	C3ZB88_BRAFL	C3Z851	C3ZB88	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	0.904
C3ZB87_BRAFL	C3Z851_BRAFL	C3ZB87	C3Z851	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	0.904
C3ZB87_BRAFL	C3ZB88_BRAFL	C3ZB87	C3ZB88	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	0.900
C3ZB88_BRAFL	C3Z851_BRAFL	C3ZB88	C3Z851	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	0.904
C3ZB88_BRAFL	C3ZB87_BRAFL	C3ZB88	C3ZB87	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	0.900
C3ZFF5_BRAFL	C3XQQ3_BRAFL	C3ZFF5	C3XQQ3	Mothers against decapentaplegic homolog.	MSC domain-containing protein.	0.432
C3ZFF5_BRAFL	C3Y795_BRAFL	C3ZFF5	C3Y795	Mothers against decapentaplegic homolog.	WD_REPEATS_REGION domain-containing protein.	0.707
C3ZFF5_BRAFL	C3Z7U5_BRAFL	C3ZFF5	C3Z7U5	Mothers against decapentaplegic homolog.	Uncharacterized protein.	0.959
C3ZFF5_BRAFL	C3Z7U6_BRAFL	C3ZFF5	C3Z7U6	Mothers against decapentaplegic homolog.	HECT domain-containing protein.	0.995