(14 nodes) Mixed, incl. NF-kappa-B/Dorsal, and Cytoplasmic sequestering of NF-kappaB network (Danio rerio)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	nfkbiab	Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha b. (312 aa)
	nfkbib	Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta. (394 aa)
	rel	V-rel avian reticuloendotheliosis viral oncogene homolog. (596 aa)
	LOC795766	ADP-ribosylation factor 2b. (783 aa)
	map3k8	Mitogen-activated protein kinase kinase kinase 8. (472 aa)
	nfkbie	Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon. (343 aa)
	nfkbiaa	Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha a. (310 aa)
	ikbkb	Inhibitor of nuclear factor kappa B kinase subunit beta. (779 aa)
	nfkb2	Nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100). (902 aa)
	map2k2b	Mitogen-activated protein kinase kinase 2b; Belongs to the protein kinase superfamily. (395 aa)
	map3k14a	Mitogen-activated protein kinase kinase kinase 14a. (825 aa)
	relb	V-rel avian reticuloendotheliosis viral oncogene homolog B. (582 aa)
	rela	V-rel avian reticuloendotheliosis viral oncogene homolog A. (455 aa)
	nfkb1	Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1. (540 aa)

Your Current Organism:

Danio rerio

NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LOC795766	ikbkb	ENSDARP00000073556	ENSDARP00000117685	ADP-ribosylation factor 2b.	Inhibitor of nuclear factor kappa B kinase subunit beta.	0.963
LOC795766	map2k2b	ENSDARP00000073556	ENSDARP00000124788	ADP-ribosylation factor 2b.	Mitogen-activated protein kinase kinase 2b; Belongs to the protein kinase superfamily.	0.458
LOC795766	map3k14a	ENSDARP00000073556	ENSDARP00000125811	ADP-ribosylation factor 2b.	Mitogen-activated protein kinase kinase kinase 14a.	0.908
LOC795766	map3k8	ENSDARP00000073556	ENSDARP00000082752	ADP-ribosylation factor 2b.	Mitogen-activated protein kinase kinase kinase 8.	0.912
ikbkb	LOC795766	ENSDARP00000117685	ENSDARP00000073556	Inhibitor of nuclear factor kappa B kinase subunit beta.	ADP-ribosylation factor 2b.	0.963
ikbkb	map3k14a	ENSDARP00000117685	ENSDARP00000125811	Inhibitor of nuclear factor kappa B kinase subunit beta.	Mitogen-activated protein kinase kinase kinase 14a.	0.963
ikbkb	map3k8	ENSDARP00000117685	ENSDARP00000082752	Inhibitor of nuclear factor kappa B kinase subunit beta.	Mitogen-activated protein kinase kinase kinase 8.	0.926
ikbkb	nfkb1	ENSDARP00000117685	ENSDARP00000135800	Inhibitor of nuclear factor kappa B kinase subunit beta.	Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1.	0.969
ikbkb	nfkb2	ENSDARP00000117685	ENSDARP00000121285	Inhibitor of nuclear factor kappa B kinase subunit beta.	Nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100).	0.850
ikbkb	nfkbiaa	ENSDARP00000117685	ENSDARP00000109941	Inhibitor of nuclear factor kappa B kinase subunit beta.	Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha a.	0.984
ikbkb	nfkbiab	ENSDARP00000117685	ENSDARP00000015303	Inhibitor of nuclear factor kappa B kinase subunit beta.	Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha b.	0.988
ikbkb	nfkbib	ENSDARP00000117685	ENSDARP00000045035	Inhibitor of nuclear factor kappa B kinase subunit beta.	Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta.	0.738
ikbkb	nfkbie	ENSDARP00000117685	ENSDARP00000089603	Inhibitor of nuclear factor kappa B kinase subunit beta.	Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon.	0.946
ikbkb	rel	ENSDARP00000117685	ENSDARP00000072078	Inhibitor of nuclear factor kappa B kinase subunit beta.	V-rel avian reticuloendotheliosis viral oncogene homolog.	0.795
ikbkb	rela	ENSDARP00000117685	ENSDARP00000133181	Inhibitor of nuclear factor kappa B kinase subunit beta.	V-rel avian reticuloendotheliosis viral oncogene homolog A.	0.677
ikbkb	relb	ENSDARP00000117685	ENSDARP00000128656	Inhibitor of nuclear factor kappa B kinase subunit beta.	V-rel avian reticuloendotheliosis viral oncogene homolog B.	0.657
map2k2b	LOC795766	ENSDARP00000124788	ENSDARP00000073556	Mitogen-activated protein kinase kinase 2b; Belongs to the protein kinase superfamily.	ADP-ribosylation factor 2b.	0.458
map2k2b	map3k14a	ENSDARP00000124788	ENSDARP00000125811	Mitogen-activated protein kinase kinase 2b; Belongs to the protein kinase superfamily.	Mitogen-activated protein kinase kinase kinase 14a.	0.458
map2k2b	map3k8	ENSDARP00000124788	ENSDARP00000082752	Mitogen-activated protein kinase kinase 2b; Belongs to the protein kinase superfamily.	Mitogen-activated protein kinase kinase kinase 8.	0.930
map2k2b	nfkbib	ENSDARP00000124788	ENSDARP00000045035	Mitogen-activated protein kinase kinase 2b; Belongs to the protein kinase superfamily.	Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta.	0.505

page 1 of 6

Server load: low (24%) [HD]

Permalink

Network

Cooccurrence

Experiments

Coexpression

Databases

Neighborhood

Textmining

Fusion

© STRING Consortium 2025

Credits

Access

Info

About