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mrto4 mrto4 nsa2 nsa2 wdr12 wdr12 rrp15 rrp15 znf622 znf622 eif6 eif6 pes pes nip7 nip7 wdr74 wdr74 noc2l noc2l mak16 mak16 rrs1 rrs1 rpf1 rpf1 bop1 bop1 ftsj3 ftsj3 rrp1 rrp1 ebna1bp2 ebna1bp2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
mrto4Ribosome assembly factor mrt4; Component of the ribosome assembly machinery. Nuclear paralog of the ribosomal protein P0, it binds pre-60S subunits at an early stage of assembly in the nucleolus, and is replaced by P0 in cytoplasmic pre-60S subunits and mature 80S ribosomes. (242 aa)
nsa2NSA2 ribosome biogenesis homolog (S. cerevisiae). (260 aa)
wdr12Ribosome biogenesis protein wdr12; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome. (422 aa)
rrp15RRP15-like protein; Belongs to the RRP15 family. (249 aa)
znf622Zinc finger protein 622. (453 aa)
eif6Eukaryotic translation initiation factor 6; Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. May also be involved in ribosome biogenesis. (245 aa)
pesPescadillo; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome. (583 aa)
nip760S ribosome subunit biogenesis protein NIP7 homolog; Required for proper 34S pre-rRNA processing and 60S ribosome subunit assembly. (180 aa)
wdr74WD repeat domain 74. (375 aa)
noc2lNOC2-like nucleolar-associated transcriptional repressor. (752 aa)
mak16Protein MAK16 homolog; Plays an essential role in early embryonic development. (305 aa)
rrs1Ribosome biogenesis regulatory protein; Involved in ribosomal large subunit assembly. Belongs to the RRS1 family. (346 aa)
rpf1Ribosome production factor 1; May be required for ribosome biogenesis. (352 aa)
bop1Ribosome biogenesis protein bop1; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome. (785 aa)
ftsj3pre-rRNA processing protein FTSJ3; Probable methyltransferase involved in the processing of the 34S pre-rRNA to 18S rRNA and in 40S ribosomal subunit formation. Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. SPB1 subfamily. (838 aa)
rrp1Ribosomal RNA-processing 1. (673 aa)
ebna1bp2EBNA1-binding protein 2. (308 aa)
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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