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abhd10a abhd10a lypla1 lypla1 lyplal1 lyplal1 notum2 notum2 lypla2 lypla2 abhd17ab abhd17ab abhd17aa abhd17aa atm atm notum1a notum1a ppt1 ppt1 apoeb apoeb apoba apoba abhd17c abhd17c abhd10b abhd10b ENSDARP00000154058 ENSDARP00000154058 notum1b notum1b apoea apoea
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
abhd10aAbhydrolase domain-containing 10a. (284 aa)
lypla1Lysophospholipase 1. (230 aa)
lyplal1Lysophospholipase-like 1. (235 aa)
notum2Carboxylesterase notum2; Carboxylesterase that mediates deacylation of target proteins (By similarity). Acts as a regulator of growth cone migration. Does not act as an inhibitor of Wnt signaling. (495 aa)
lypla2Lysophospholipase 2. (232 aa)
abhd17abAbhydrolase domain-containing 17Ab. (324 aa)
abhd17aaAbhydrolase domain-containing 17Aa. (337 aa)
atmNon-specific serine/threonine protein kinase. (3091 aa)
notum1aPalmitoleoyl-protein carboxylesterase notum1a; Carboxylesterase that acts as a key negative regulator of the Wnt signaling pathway. Acts by specifically mediating depalmitoleoylation of WNT proteins. Serine palmitoleoylation of WNT proteins is required for efficient binding to frizzled receptors (By similarity); Belongs to the pectinacetylesterase family. Notum subfamily. (500 aa)
ppt1Palmitoyl-protein thioesterase 1 (ceroid-lipofuscinosis, neuronal 1, infantile). (303 aa)
apoebApolipoprotein Eb; APOE is an apolipoprotein, a protein associating with lipid particles, that mainly functions in lipoprotein-mediated lipid transport between organs via the plasma and interstitial fluids. APOE is a core component of plasma lipoproteins and is involved in their production, conversion and clearance. Apoliproteins are amphipathic molecules that interact both with lipids of the lipoprotein particle core and the aqueous environment of the plasma. Belongs to the apolipoprotein A1/A4/E family. (281 aa)
apobaApolipoprotein Ba. (4418 aa)
abhd17cAlpha/beta hydrolase domain-containing protein 17C; Hydrolyzes fatty acids from S-acylated cysteine residues in proteins. Has depalmitoylating activity towards nras. Belongs to the AB hydrolase superfamily. ABHD17 family. (294 aa)
abhd10bTransgelin 3b. (289 aa)
ENSDARP00000154058Uncharacterized protein. (105 aa)
notum1bInactive palmitoleoyl-protein carboxylesterase notum1b. (49 aa)
apoeaApolipoprotein Ea. (269 aa)
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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