| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| fgf18a | flt1 | ENSDARP00000106596 | ENSDARP00000002466 | Fibroblast growth factor 18a; Belongs to the heparin-binding growth factors family. | Vascular endothelial growth factor receptor 1 isoform 1 precursor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. | 0.737 |
| fgf18a | flt4 | ENSDARP00000106596 | ENSDARP00000133227 | Fibroblast growth factor 18a; Belongs to the heparin-binding growth factors family. | Vascular endothelial growth factor receptor 3; Tyrosine-protein kinase that acts as a cell-surface receptor for vegf or vegfc. Combinations of multiple VEGF receptors are required for development of different blood vessel types in the embryo. Involved in angiogenesis, specifically in VEGF-induced sprouting of new blood vessels, but not required for proper vasculogenesis or hematopoiesis. | 0.737 |
| fgf18a | kdr | ENSDARP00000106596 | ENSDARP00000049203 | Fibroblast growth factor 18a; Belongs to the heparin-binding growth factors family. | Vascular endothelial growth factor receptor 2; Receptor for VEGF or VEGFC. Has a tyrosine-protein kinase activity. Combinations of multiple VEGF receptors are required for development of different blood vessel types in the embryo. Involved in angiogenesis, specifically in VEGF-induced sprouting of new blood vessels. Particularly involved in artery formation. Does not appear to be required for hematopoiesis. | 0.758 |
| fgf24 | flt1 | ENSDARP00000054876 | ENSDARP00000002466 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. | Vascular endothelial growth factor receptor 1 isoform 1 precursor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. | 0.737 |
| fgf24 | flt4 | ENSDARP00000054876 | ENSDARP00000133227 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. | Vascular endothelial growth factor receptor 3; Tyrosine-protein kinase that acts as a cell-surface receptor for vegf or vegfc. Combinations of multiple VEGF receptors are required for development of different blood vessel types in the embryo. Involved in angiogenesis, specifically in VEGF-induced sprouting of new blood vessels, but not required for proper vasculogenesis or hematopoiesis. | 0.737 |
| fgf24 | kdr | ENSDARP00000054876 | ENSDARP00000049203 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. | Vascular endothelial growth factor receptor 2; Receptor for VEGF or VEGFC. Has a tyrosine-protein kinase activity. Combinations of multiple VEGF receptors are required for development of different blood vessel types in the embryo. Involved in angiogenesis, specifically in VEGF-induced sprouting of new blood vessels. Particularly involved in artery formation. Does not appear to be required for hematopoiesis. | 0.758 |
| flt1 | fgf18a | ENSDARP00000002466 | ENSDARP00000106596 | Vascular endothelial growth factor receptor 1 isoform 1 precursor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. | Fibroblast growth factor 18a; Belongs to the heparin-binding growth factors family. | 0.737 |
| flt1 | fgf24 | ENSDARP00000002466 | ENSDARP00000054876 | Vascular endothelial growth factor receptor 1 isoform 1 precursor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. | 0.737 |
| flt1 | nrp1a | ENSDARP00000002466 | ENSDARP00000140900 | Vascular endothelial growth factor receptor 1 isoform 1 precursor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. | Neuropilin-1a; Receptor involved in the development of the cardiovascular system, in angiogenesis, in the formation of certain neuronal circuits and in organogenesis outside the nervous system. It mediates the chemorepulsant activity of semaphorins. Regulates angiogenesis through a VEGF-dependent pathway. | 0.951 |
| flt1 | pgfb | ENSDARP00000002466 | ENSDARP00000127609 | Vascular endothelial growth factor receptor 1 isoform 1 precursor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. | Placental growth factor b; Belongs to the PDGF/VEGF growth factor family. | 0.954 |
| flt1 | vegfaa | ENSDARP00000002466 | ENSDARP00000133415 | Vascular endothelial growth factor receptor 1 isoform 1 precursor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. | Vascular endothelial growth factor A-A; Growth factor active in angiogenesis, vasculogenesis and endothelial cell growth. Induces endothelial cell proliferation, promotes cell migration, inhibits apoptosis, and induces permeabilization of blood vessels. Acts both upstream of kdr and tie1 to stimulate endothelial cell differentiation, and upstream of gata1 to stimulate hematopoietic cell differentiation. | 0.990 |
| flt1 | vegfba | ENSDARP00000002466 | ENSDARP00000109240 | Vascular endothelial growth factor receptor 1 isoform 1 precursor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. | Vascular endothelial growth factor Ba; Belongs to the PDGF/VEGF growth factor family. | 0.685 |
| flt1 | vegfbb | ENSDARP00000002466 | ENSDARP00000114926 | Vascular endothelial growth factor receptor 1 isoform 1 precursor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. | Vascular endothelial growth factor Bb; Belongs to the PDGF/VEGF growth factor family. | 0.730 |
| flt1 | vegfc | ENSDARP00000002466 | ENSDARP00000092263 | Vascular endothelial growth factor receptor 1 isoform 1 precursor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. | Vascular endothelial growth factor C; Belongs to the PDGF/VEGF growth factor family. | 0.988 |
| flt1 | vegfd | ENSDARP00000002466 | ENSDARP00000121602 | Vascular endothelial growth factor receptor 1 isoform 1 precursor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. | Vascular endothelial growth factor D; Belongs to the PDGF/VEGF growth factor family. | 0.975 |
| flt4 | fgf18a | ENSDARP00000133227 | ENSDARP00000106596 | Vascular endothelial growth factor receptor 3; Tyrosine-protein kinase that acts as a cell-surface receptor for vegf or vegfc. Combinations of multiple VEGF receptors are required for development of different blood vessel types in the embryo. Involved in angiogenesis, specifically in VEGF-induced sprouting of new blood vessels, but not required for proper vasculogenesis or hematopoiesis. | Fibroblast growth factor 18a; Belongs to the heparin-binding growth factors family. | 0.737 |
| flt4 | fgf24 | ENSDARP00000133227 | ENSDARP00000054876 | Vascular endothelial growth factor receptor 3; Tyrosine-protein kinase that acts as a cell-surface receptor for vegf or vegfc. Combinations of multiple VEGF receptors are required for development of different blood vessel types in the embryo. Involved in angiogenesis, specifically in VEGF-induced sprouting of new blood vessels, but not required for proper vasculogenesis or hematopoiesis. | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. | 0.737 |
| flt4 | kdr | ENSDARP00000133227 | ENSDARP00000049203 | Vascular endothelial growth factor receptor 3; Tyrosine-protein kinase that acts as a cell-surface receptor for vegf or vegfc. Combinations of multiple VEGF receptors are required for development of different blood vessel types in the embryo. Involved in angiogenesis, specifically in VEGF-induced sprouting of new blood vessels, but not required for proper vasculogenesis or hematopoiesis. | Vascular endothelial growth factor receptor 2; Receptor for VEGF or VEGFC. Has a tyrosine-protein kinase activity. Combinations of multiple VEGF receptors are required for development of different blood vessel types in the embryo. Involved in angiogenesis, specifically in VEGF-induced sprouting of new blood vessels. Particularly involved in artery formation. Does not appear to be required for hematopoiesis. | 0.477 |
| flt4 | nrp1a | ENSDARP00000133227 | ENSDARP00000140900 | Vascular endothelial growth factor receptor 3; Tyrosine-protein kinase that acts as a cell-surface receptor for vegf or vegfc. Combinations of multiple VEGF receptors are required for development of different blood vessel types in the embryo. Involved in angiogenesis, specifically in VEGF-induced sprouting of new blood vessels, but not required for proper vasculogenesis or hematopoiesis. | Neuropilin-1a; Receptor involved in the development of the cardiovascular system, in angiogenesis, in the formation of certain neuronal circuits and in organogenesis outside the nervous system. It mediates the chemorepulsant activity of semaphorins. Regulates angiogenesis through a VEGF-dependent pathway. | 0.855 |
| flt4 | pgfb | ENSDARP00000133227 | ENSDARP00000127609 | Vascular endothelial growth factor receptor 3; Tyrosine-protein kinase that acts as a cell-surface receptor for vegf or vegfc. Combinations of multiple VEGF receptors are required for development of different blood vessel types in the embryo. Involved in angiogenesis, specifically in VEGF-induced sprouting of new blood vessels, but not required for proper vasculogenesis or hematopoiesis. | Placental growth factor b; Belongs to the PDGF/VEGF growth factor family. | 0.954 |