(43 nodes) Preribosome network (Danio rerio)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	emg1	EMG1 N1-specific pseudouridine methyltransferase. (238 aa)
	imp4	IMP4, U3 small nucleolar ribonucleoprotein, homolog (Yeast). (291 aa)
	rrp15	RRP15-like protein; Belongs to the RRP15 family. (249 aa)
	noc4l	Nucleolar complex protein 4 homolog. (525 aa)
	riok3	Serine/threonine-protein kinase RIO3; Belongs to the protein kinase superfamily. RIO-type Ser/Thr kinase family. (507 aa)
	riok2	RIO kinase 2 (yeast). (512 aa)
	nob1	RNA-binding protein NOB1; May play a role in mRNA degradation. Belongs to the NOB1 family. (440 aa)
	fcf1	FCF1 rRNA-processing protein. (198 aa)
	utp23	UTP23 small subunit processome component. (257 aa)
	rrp7a	Ribosomal RNA-processing 7 homolog A. (280 aa)
	utp6	UTP6 small subunit processome component. (594 aa)
	utp18	UTP18 small subunit processome component. (104 aa)
	utp20	UTP20 small subunit processome component. (2794 aa)
	rrp1	Ribosomal RNA-processing 1. (673 aa)
	nop14	NOP14 nucleolar protein homolog (yeast). (767 aa)
	rrp9	Ribosomal RNA-processing 9, U3 small nucleolar RNA-binding protein. (471 aa)
	imp3	IMP U3 small nucleolar ribonucleoprotein 3. (183 aa)
	pes	Pescadillo; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome. (583 aa)
	mphosph10	U3 small nucleolar ribonucleoprotein protein MPP10; Component of the 60-80S U3 small nucleolar ribonucleoprotein (U3 snoRNP). Required for the early cleavages during pre-18S ribosomal RNA processing; Belongs to the MPP10 family. (695 aa)
	bop1	Ribosome biogenesis protein bop1; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome. (785 aa)
	hunk	Hormonally up-regulated Neu-associated kinase. (609 aa)
	pin4	Peptidyl-prolyl cis-trans isomerase NIMA-interacting 4; May be involved as a ribosomal RNA processing factor in ribosome biogenesis. Binds to DNA (By similarity). (128 aa)
	wdr3	WD repeat domain 3. (938 aa)
	riok1	Serine/threonine-protein kinase RIO1; Belongs to the protein kinase superfamily. RIO-type Ser/Thr kinase family. (552 aa)
	nol10	Nucleolar protein 10. (722 aa)
	wdr36	WD repeat domain 36. (896 aa)
	wdr12	Ribosome biogenesis protein wdr12; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome. (422 aa)
	nsa2	NSA2 ribosome biogenesis homolog (S. cerevisiae). (260 aa)
	mrto4	Ribosome assembly factor mrt4; Component of the ribosome assembly machinery. Nuclear paralog of the ribosomal protein P0, it binds pre-60S subunits at an early stage of assembly in the nucleolus, and is replaced by P0 in cytoplasmic pre-60S subunits and mature 80S ribosomes. (242 aa)
	bysl	Bystin-like. (466 aa)
	ltv1	Protein LTV1 homolog; Belongs to the LTV1 family. (473 aa)
	cmss1	Protein CMSS1; Belongs to the CMS1 family. (292 aa)
	LOC101887148	Si:ch211-197l9.5. (382 aa)
	fbxw9	F-box and WD repeat domain-containing 9. (485 aa)
	UTP14C	Si:dkey-251i10.3. (785 aa)
	nop9	Uncharacterized protein. (604 aa)
	pwp2h	PWP2 small subunit processome component. (937 aa)
	mak16	Protein MAK16 homolog; Plays an essential role in early embryonic development. (305 aa)
	rsl24d1	Probable ribosome biogenesis protein RLP24; Involved in the biogenesis of the 60S ribosomal subunit. Ensures the docking of GTPBP4/NOG1 to pre-60S particles (By similarity). (161 aa)
	noc2l	NOC2-like nucleolar-associated transcriptional repressor. (752 aa)
	nol6	Nucleolar protein 6. (1153 aa)
	F1QVS9_DANRE	Si:ch73-142c19.1. (471 aa)
	utp3	UTP3 small subunit processome component. (470 aa)

Your Current Organism:

Danio rerio

NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
UTP14C	bop1	ENSDARP00000105713	ENSDARP00000120969	Si:dkey-251i10.3.	Ribosome biogenesis protein bop1; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	0.776
UTP14C	bysl	ENSDARP00000105713	ENSDARP00000001346	Si:dkey-251i10.3.	Bystin-like.	0.995
UTP14C	cmss1	ENSDARP00000105713	ENSDARP00000018592	Si:dkey-251i10.3.	Protein CMSS1; Belongs to the CMS1 family.	0.491
UTP14C	emg1	ENSDARP00000105713	ENSDARP00000073952	Si:dkey-251i10.3.	EMG1 N1-specific pseudouridine methyltransferase.	0.988
UTP14C	fcf1	ENSDARP00000105713	ENSDARP00000130801	Si:dkey-251i10.3.	FCF1 rRNA-processing protein.	0.992
UTP14C	imp3	ENSDARP00000105713	ENSDARP00000148639	Si:dkey-251i10.3.	IMP U3 small nucleolar ribonucleoprotein 3.	0.978
UTP14C	imp4	ENSDARP00000105713	ENSDARP00000071213	Si:dkey-251i10.3.	IMP4, U3 small nucleolar ribonucleoprotein, homolog (Yeast).	0.996
UTP14C	ltv1	ENSDARP00000105713	ENSDARP00000017491	Si:dkey-251i10.3.	Protein LTV1 homolog; Belongs to the LTV1 family.	0.906
UTP14C	mak16	ENSDARP00000105713	ENSDARP00000098580	Si:dkey-251i10.3.	Protein MAK16 homolog; Plays an essential role in early embryonic development.	0.908
UTP14C	mphosph10	ENSDARP00000105713	ENSDARP00000025759	Si:dkey-251i10.3.	U3 small nucleolar ribonucleoprotein protein MPP10; Component of the 60-80S U3 small nucleolar ribonucleoprotein (U3 snoRNP). Required for the early cleavages during pre-18S ribosomal RNA processing; Belongs to the MPP10 family.	0.999
UTP14C	mrto4	ENSDARP00000105713	ENSDARP00000002982	Si:dkey-251i10.3.	Ribosome assembly factor mrt4; Component of the ribosome assembly machinery. Nuclear paralog of the ribosomal protein P0, it binds pre-60S subunits at an early stage of assembly in the nucleolus, and is replaced by P0 in cytoplasmic pre-60S subunits and mature 80S ribosomes.	0.791
UTP14C	nob1	ENSDARP00000105713	ENSDARP00000125998	Si:dkey-251i10.3.	RNA-binding protein NOB1; May play a role in mRNA degradation. Belongs to the NOB1 family.	0.905
UTP14C	noc2l	ENSDARP00000105713	ENSDARP00000086095	Si:dkey-251i10.3.	NOC2-like nucleolar-associated transcriptional repressor.	0.938
UTP14C	noc4l	ENSDARP00000105713	ENSDARP00000067000	Si:dkey-251i10.3.	Nucleolar complex protein 4 homolog.	0.998
UTP14C	nol10	ENSDARP00000105713	ENSDARP00000018924	Si:dkey-251i10.3.	Nucleolar protein 10.	0.998
UTP14C	nol6	ENSDARP00000105713	ENSDARP00000077729	Si:dkey-251i10.3.	Nucleolar protein 6.	0.999
UTP14C	nop14	ENSDARP00000105713	ENSDARP00000140126	Si:dkey-251i10.3.	NOP14 nucleolar protein homolog (yeast).	0.998
UTP14C	nop9	ENSDARP00000105713	ENSDARP00000104423	Si:dkey-251i10.3.	Uncharacterized protein.	0.848
UTP14C	nsa2	ENSDARP00000105713	ENSDARP00000003036	Si:dkey-251i10.3.	NSA2 ribosome biogenesis homolog (S. cerevisiae).	0.441
UTP14C	pes	ENSDARP00000105713	ENSDARP00000026992	Si:dkey-251i10.3.	Pescadillo; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	0.834

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