STRINGSTRING
grip2b grip2b lzts1 lzts1 psen2 psen2 psen1 psen1 sez6a sez6a cript cript sez6b sez6b cnih3 cnih3 cnih2 cnih2 frmpd1b frmpd1b
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
grip2bGlutamate receptor-interacting protein 2b. (1119 aa)
lzts1Leucine zipper, putative tumor suppressor 1. (712 aa)
psen2Presenilin-2; Probable catalytic subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors; Belongs to the peptidase A22A family. (441 aa)
psen1Presenilin-1; Catalytic subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors and APP (amyloid- beta precursor protein). Requires the presence of the other members of the gamma-secretase complex for protease activity. Plays a role in Notch and Wnt signaling cascades and regulation of downstream processes via its role in processing key regulatory proteins (By similarity); Belongs to the peptidase A22A family. (456 aa)
sez6aSeizure-related 6 homolog a. (970 aa)
criptCysteine-rich PDZ-binding protein. (101 aa)
sez6bSeizure-related 6 homolog b. (1027 aa)
cnih3Cornichon family AMPA receptor auxiliary protein 3. (159 aa)
cnih2Protein cornichon homolog 2; Regulates the trafficking and gating properties of AMPA- selective glutamate receptors (AMPARs); Belongs to the cornichon family. (160 aa)
frmpd1bFERM and PDZ domain-containing 1b. (1656 aa)
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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