STRINGSTRING
rgs11 rgs11 farsa farsa LOC100538179 LOC100538179 foxj1a foxj1a foxo1a foxo1a irf5 irf5 foxq1a foxq1a foxa1 foxa1 anapc2 anapc2 irf6 irf6 foxo6a foxo6a asmt asmt erfl1 erfl1 dvl3 dvl3 ENSDARP00000142167 ENSDARP00000142167 ENSDARP00000142521 ENSDARP00000142521 ENSDARP00000142541 ENSDARP00000142541 ENSDARP00000142554 ENSDARP00000142554 ENSDARP00000142564 ENSDARP00000142564 ENSDARP00000142593 ENSDARP00000142593 foxj3 foxj3 blm blm larp6a larp6a elf2b elf2b rgs9a rgs9a e2f4 e2f4 foxn1 foxn1 larp1b larp1b foxa2 foxa2 rad21a rad21a plek2 plek2 eif3c eif3c arid2 arid2 cops2 cops2 foxr1 foxr1 stn1 stn1 pa2g4b pa2g4b FOXK2 FOXK2 etv4 etv4 foxg1b foxg1b foxn4 foxn4 gtf2e2 gtf2e2 psmd11b psmd11b cops3 cops3 tfdp1b tfdp1b foxf1 foxf1 eif3m eif3m psmd3 psmd3 spi1b spi1b irf10 irf10 rfx4 rfx4 pkz pkz foxo3a foxo3a elf2a elf2a rfx2 rfx2 rfx3 rfx3 ssb ssb foxd1 foxd1 foxk2 foxk2 etv2 etv2 rps19 rps19 E7F5A4_DANRE E7F5A4_DANRE depdc1a depdc1a SPDEF SPDEF riok2 riok2 zgc:113424 zgc:113424 ddrgk1 ddrgk1 rpa2 rpa2 mnd1 mnd1 foxk1 foxk1 h1-0 h1-0 e2f5 e2f5 cul3a cul3a pa2g4a pa2g4a foxp2 foxp2 foxl2a foxl2a cops4 cops4 E7FAK0_DANRE E7FAK0_DANRE foxp1b foxp1b etv5b etv5b zgc:110216 zgc:110216 ehf ehf fli1a fli1a depdc7a depdc7a foxc1b foxc1b tfdp1a tfdp1a foxh1 foxh1 prex1 prex1 foxo4 foxo4 irf8 irf8 vps36 vps36 rad21l1 rad21l1 foxj2 foxj2 snf8 snf8 foxp3a foxp3a asmt2 asmt2 foxo1b foxo1b larp4b larp4b erfl3 erfl3 foxe3 foxe3 fev fev dvl3a dvl3a cdt1 cdt1 eif3k eif3k foxl2b foxl2b LOC565819 LOC565819 gabpa gabpa foxi2 foxi2 larp7 larp7 gtf2f2a gtf2f2a ell2 ell2 elk4 elk4 foxf2b foxf2b irf7 irf7 dvl1b dvl1b foxg1a foxg1a psmd13 psmd13 rgs7a rgs7a prex2 prex2 LOC569982 LOC569982 spi1a spi1a snrnp200 snrnp200 rapgef3 rapgef3 E7FFJ8_DANRE E7FFJ8_DANRE foxp4 foxp4 cul5a cul5a zgc:162612 zgc:162612 rfx7a rfx7a helq helq foxb1b foxb1b foxc1a foxc1a e2f8 e2f8 foxa foxa psmd12 psmd12 eif3ea eif3ea ascc3 ascc3 foxj1b foxj1b foxo6b foxo6b foxd3 foxd3 elf1 elf1 foxp1a foxp1a si:dkey-7e14.3 si:dkey-7e14.3 etv5a etv5a F2Z4R0_DANRE F2Z4R0_DANRE foxb1a foxb1a cul5b cul5b cul1a cul1a metap2a metap2a e2f3 e2f3 E7F8J2_DANRE E7F8J2_DANRE A2CEM5_DANRE A2CEM5_DANRE gpr155a gpr155a cul3b cul3b ets2 ets2 hsf5 hsf5 etv1 etv1 psmd11a psmd11a shprh shprh R4GEY3_DANRE R4GEY3_DANRE vps25 vps25 irf3 irf3 foxn3 foxn3 pikfyve pikfyve rfx5 rfx5 cul4b cul4b elk3 elk3 irf9 irf9 cul2 cul2 E9QFU6_DANRE E9QFU6_DANRE rad21b rad21b hsf1 hsf1 LOC100332095 LOC100332095 rgs6 rgs6 rgs9b rgs9b e2f7 e2f7 foxd2 foxd2 rfx6 rfx6 erf erf irf2a irf2a foxg1c foxg1c si:rp71-45k5.2 si:rp71-45k5.2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
rgs11Regulator of G protein-signaling 11. (471 aa)
farsaPhenylalanine--tRNA ligase alpha subunit. (497 aa)
LOC100538179Regulatory factor X7b. (1551 aa)
foxj1aForkhead box protein J1-A; Key transcription factor required for motile ciliogenesis. Activates genes essential for motile cilia formation and function. Its activity is sufficient for ectopic development of cilia that resemble motile cilia. (458 aa)
foxo1aForkhead box protein O1-A; Transcriptional regulator of cell cycle arrest required for cellular stress responses (By similarity). May be involved in regulating cellular homeostasis in the eye. (652 aa)
irf5Interferon regulatory factor 5. (516 aa)
foxq1aForkhead box Q1a. (312 aa)
foxa1Forkhead box A1. (427 aa)
anapc2Anaphase-promoting complex subunit 2; Belongs to the cullin family. (802 aa)
irf6Interferon regulatory factor 6. (492 aa)
foxo6aForkhead box O6 a. (594 aa)
asmtAcetylserotonin O-methyltransferase. (344 aa)
erfl1Ets2 repressor factor-like 1. (473 aa)
dvl3Dishevelled segment polarity protein 3b. (706 aa)
ENSDARP00000142167Si:ch73-368j24.11. (205 aa)
ENSDARP00000142521Si:ch1073-153i20.4. (201 aa)
ENSDARP00000142541Si:dkey-23a13.9. (201 aa)
ENSDARP00000142554Si:dkey-23a13.17. (206 aa)
ENSDARP00000142564Si:ch1073-159d7.7. (197 aa)
ENSDARP00000142593Si:ch73-368j24.12. (201 aa)
foxj3Forkhead box J3. (596 aa)
blmBLM RecQ-like helicase. (1439 aa)
larp6aLa ribonucleoprotein 6, translational regulator a. (485 aa)
elf2bE74-like factor 2b (ets domain transcription factor). (607 aa)
rgs9aRegulator of G protein-signaling 9a. (480 aa)
e2f4E2F transcription factor 4. (404 aa)
foxn1Forkhead box N1. (565 aa)
larp1bLa ribonucleoprotein 1B. (1076 aa)
foxa2Forkhead box protein A2; May play a crucial role in specification of both the axial mesendoderm and the ventral nervous system. (409 aa)
rad21aDouble-strand-break repair protein rad21 homolog A; Double-strand-break repair protein rad21 homolog: As a member of the cohesin complex, involved in sister chromatid cohesion from the time of DNA replication in S phase to their segregation in mitosis, a function that is essential for proper chromosome segregation, post- replicative DNA repair, and the prevention of inappropriate recombination between repetitive regions. The cohesin complex may also play a role in spindle pole assembly during mitosis (By similarity). In interphase, cohesins may function in the control of gene expressio [...] (643 aa)
plek2Plek2 protein. (361 aa)
eif3cEukaryotic translation initiation factor 3 subunit C; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. (926 aa)
arid2AT-rich interactive domain 2 (ARID, RFX-like). (1572 aa)
cops2COP9 signalosome complex subunit 2; Essential component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes. The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of E3 ligase complexes, leading to modify the Ubl ligase activity. (443 aa)
foxr1Zgc:171734 protein. (321 aa)
stn1CST complex subunit STN1; Component of the CST complex proposed to act as a specialized replication factor promoting DNA replication under conditions of replication stress or natural replication barriers such as the telomere duplex. The CST complex binds single-stranded DNA with high affinity in a sequence-independent manner, while isolated subunits bind DNA with low affinity by themselves. Initially the CST complex has been proposed to protect telomeres from DNA degradation. However, the CST complex has been shown to be involved in several aspects of telomere replication. Belongs to t [...] (368 aa)
pa2g4bProliferation-associated 2G4, b. (394 aa)
FOXK2Si:ch211-262e15.1. (597 aa)
etv4ETS translocation variant 4; Transcriptional activator that binds to the (5'-CCGGA[AT]-3') motif. May control the acquisition of specific cell fates at an early stage during development of the somites and nervous system. May mediate the cellular effects of the fibroblast growth factors on embryogenesis. (494 aa)
foxg1bForkhead box G1b. (341 aa)
foxn4Forkhead box protein N4; Transcription factor essential for neural and some non-neural tissues development. Binds to an 11-bp consensus sequence containing the invariant tetranucleotide 5'-ACGC-3'. During development of the central nervous system, required to specify the amacrine and horizontal cell fates from multipotent retinal progenitors while suppressing the alternative photoreceptor cell fates. Drives commitment of p2 progenitors to the V2b interneuron fates during spinal cord neurogenesis. In development of non-neural tissues, plays an essential role in the specification of the [...] (550 aa)
gtf2e2Transcription initiation factor IIE subunit beta; Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase. (291 aa)
psmd11b26S proteasome non-ATPase regulatory subunit 11B; Component of the lid subcomplex of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. In the complex, psmd11b is required for proteasome assembly (By similarity). (422 aa)
cops3COP9 signalosome complex subunit 3; Component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes (By similarity). The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of E3 ligase complexes, leading to modify the Ubl ligase activity (By similarity). (424 aa)
tfdp1bTranscription factor. (385 aa)
foxf1Forkhead box protein F1. (380 aa)
eif3mEukaryotic translation initiation factor 3 subunit M; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. (375 aa)
psmd3Proteasome (Prosome, macropain) 26S subunit, non-ATPase, 3. (503 aa)
spi1bSI:bY184L24.2.1 (Transcription factor spi1). (296 aa)
irf10Interferon regulatory factor 10. (392 aa)
rfx4Transcription factor RFX4; May activate transcription by interacting directly with the X-box; Belongs to the RFX family. (735 aa)
pkzProtein kinase-containing Z-DNA-binding domains. (511 aa)
foxo3aForkhead box O3A. (643 aa)
elf2aE74-like factor 2a (ets domain transcription factor). (514 aa)
rfx2DNA-binding protein RFX2; Transcription factor that acts as a key regulator of ciliogenesis. Specifically regulates expression of genes required for cilium assembly and function. Recognizes and binds the X-box, a regulatory motif with DNA sequence 5'-GTNRCC(0-3N)RGYAAC-3' present on promoters (By similarity). Belongs to the RFX family. (734 aa)
rfx3Transcription factor RFX3; Transcription factor required for ciliogenesis and islet cell differentiation during endocrine pancreas development; Belongs to the RFX family. (765 aa)
ssbSmall RNA-binding exonuclease protection factor La. (401 aa)
foxd1Forkhead box D1. (343 aa)
foxk2Forkhead box K2. (544 aa)
etv2ETS variant transcription factor 2. (366 aa)
rps19Ribosomal protein S19. (146 aa)
E7F5A4_DANRESi:dkey-261m9.12. (199 aa)
depdc1aDEP domain-containing protein 1A. (800 aa)
SPDEFSAM pointed domain containing ETS transcription factor. (325 aa)
riok2RIO kinase 2 (yeast). (512 aa)
zgc:113424Zgc:113424. (300 aa)
ddrgk1DDRGK domain-containing protein 1; By regulating the post-translational modification of specific proteins, may play a role in different cellular process (By similarity). Plays a role in cartilage development through SOX9, inhibiting the ubiquitin-mediated proteasomal degradation of this transcriptional regulator. (124 aa)
rpa2Replication protein A2. (271 aa)
mnd1Meiotic nuclear division protein 1 homolog; Required for proper homologous chromosome pairing and efficient cross-over and intragenic recombination during meiosis. Stimulates both DMC1- and RAD51-mediated homologous strand assimilation, which is required for the resolution of meiotic double- strand breaks (By similarity); Belongs to the MND1 family. (220 aa)
foxk1Forkhead box K1. (639 aa)
h1-0H1 histone family, member 0. (199 aa)
e2f5E2F transcription factor 5. (363 aa)
cul3aCullin 3a; Belongs to the cullin family. (774 aa)
pa2g4aNovel protein similar to human proliferation-associated 2G4 protein (PA2G4). (392 aa)
foxp2Forkhead box P2. (697 aa)
foxl2aForkhead box L2-1. (306 aa)
cops4COP9 signalosome complex subunit 4; Component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes (By similarity). The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of E3 ligase complexes, leading to modify the Ubl ligase activity (By similarity). (406 aa)
E7FAK0_DANRESi:ch211-113a14.24. (199 aa)
foxp1bForkhead box protein P1-B; Transcriptional repressor. (659 aa)
etv5bETS variant transcription factor 5b. (524 aa)
zgc:110216Zgc:110216. (201 aa)
ehfEts homologous factor. (289 aa)
fli1aFli-1 proto-oncogene, ETS transcription factor a. (451 aa)
depdc7aDEP domain-containing protein 7; Belongs to the DEPDC7 family. (515 aa)
foxc1bForkhead box C1-B; DNA-binding transcriptional factor that plays a role in a broad range of cellular and developmental processes such as eye, bones, cardiovascular, kidney and skin development. Acts either as a transcriptional activator or repressor. Binds to the consensus binding site 5'-[G/C][A/T]AAA[T/C]AA[A/C]-3' in promoter of target genes. Upon DNA-binding, promotes DNA bending. Required for cell viability and resistance to oxidative stress in the eye. Promotes cell growth inhibition by stopping the cell cycle in the G1 phase through TGFB1- mediated signals. Involved in epithelia [...] (433 aa)
tfdp1aTranscription factor. (409 aa)
foxh1Forkhead box protein H1; Transcriptional activator. Activates an activin response element (ARE). Recognizes and binds to the DNA sequence 5'- TGT[GT][GT]ATT-3'. Modulator of nodal signaling required for organizer formation. Also required for the development of dorsal axial structures and left-right symmetry. (472 aa)
prex1Phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1. (1622 aa)
foxo4Forkhead box O4. (626 aa)
irf8Interferon regulatory factor 8. (423 aa)
vps36Vacuolar protein-sorting-associated protein 36; Component of the ESCRT-II complex (endosomal sorting complex required for transport II), which is required for multivesicular body (MVB) formation and sorting of endosomal cargo proteins into MVBs. The MVB pathway mediates delivery of transmembrane proteins into the lumen of the lysosome for degradation. The ESCRT-II complex is probably involved in the recruitment of the ESCRT-III complex. (382 aa)
rad21l1RAD21 cohesin complex component-like 1. (546 aa)
foxj2Forkhead box J2. (516 aa)
snf8Vacuolar-sorting protein SNF8; Component of the endosomal sorting complex required for transport II (ESCRT-II), which is required for multivesicular body (MVB) formation and sorting of endosomal cargo proteins into MVBs. The MVB pathway mediates delivery of transmembrane proteins into the lumen of the lysosome for degradation. The ESCRT-II complex is probably involved in the recruitment of the ESCRT-III complex (By similarity). (258 aa)
foxp3aForkhead box protein. (419 aa)
asmt2Acetylserotonin O-methyltransferase 2. (348 aa)
foxo1bForkhead box protein O1-B; Transcriptional regulator of cell cycle arrest required for cellular stress responses. (629 aa)
larp4bLa ribonucleoprotein 4B. (723 aa)
erfl3Ets2 repressor factor-like 3. (668 aa)
foxe3Forkhead box E3. (422 aa)
fevProtein FEV; Functions as a transcriptional regulator. Functions in the differentiation and the maintenance of the central serotonergic neurons. May play a role in cell growth (By similarity); Belongs to the ETS family. (235 aa)
dvl3aDishevelled segment polarity protein 3a. (676 aa)
cdt1Chromatin licensing and DNA replication factor 1. (678 aa)
eif3kEukaryotic translation initiation factor 3 subunit K; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. (219 aa)
foxl2bForkhead box L2-like protein. (285 aa)
LOC565819Si:ch211-13k12.2. (593 aa)
gabpaGA-binding protein transcription factor, alpha subunit. (455 aa)
foxi2Forkhead box I2. (383 aa)
larp7La-related protein 7; Negative transcriptional regulator of polymerase II genes, acting by means of the 7SK RNP system. Within the 7SK RNP complex, the positive transcription elongation factor b (P-TEFb) is sequestered in an inactive form, preventing RNA polymerase II phosphorylation and subsequent transcriptional elongation. (555 aa)
gtf2f2aGeneral transcription factor IIF subunit 2; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. This subunit shows ATP-dependent DNA-helicase activity. (265 aa)
ell2Elongation factor, RNA polymerase II, 2. (655 aa)
elk4ETS transcription factor ELK4. (443 aa)
foxf2bForkhead box F2b. (429 aa)
irf7Interferon regulatory factor 7. (422 aa)
dvl1bDishevelled segment polarity protein 1b. (716 aa)
foxg1aForkhead box G1a. (420 aa)
psmd13Proteasome (Prosome, macropain) 26S subunit, non-ATPase, 13. (378 aa)
rgs7aRegulator of G protein-signaling 7a. (459 aa)
prex2Phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2. (1600 aa)
LOC569982Zgc:163061 protein. (115 aa)
spi1aSpi-1 proto-oncogene a. (257 aa)
snrnp200Small nuclear ribonucleoprotein 200 (U5). (2134 aa)
rapgef3Rap guanine nucleotide exchange factor (GEF) 3. (867 aa)
E7FFJ8_DANRESi:ch211-160f23.5. (438 aa)
foxp4Forkhead box P4. (696 aa)
cul5aCullin 5a; Belongs to the cullin family. (780 aa)
zgc:162612Zgc:162612 protein. (308 aa)
rfx7aRegulatory factor X7a. (1509 aa)
helqHelicase, POLQ-like. (1010 aa)
foxb1bForkhead box B1b. (296 aa)
foxc1aForkhead box C1-A; DNA-binding transcriptional factor that plays a role in a broad range of cellular and developmental processes such as eye, bones, cardiovascular, kidney and skin development. Acts either as a transcriptional activator or repressor. Binds to the consensus binding site 5'-[G/C][A/T]AAA[T/C]AA[A/C]-3' in promoter of target genes. Upon DNA-binding, promotes DNA bending. Required for cell viability and resistance to oxidative stress in the eye. Promotes cell growth inhibition by stopping the cell cycle in the G1 phase through TGFB1- mediated signals. Involved in epithelia [...] (476 aa)
e2f8Transcription factor E2F8; Atypical E2F transcription factor that participates in various processes such as angiogenesis and polyploidization of specialized cells. Mainly acts as a transcription repressor that binds DNA independently of DP proteins and specifically recognizes the E2 recognition site 5'-TTTC[CG]CGC-3'. Directly represses transcription of classical E2F transcription factors such as e2f1. Acts as a regulator of S-phase by recognizing and binding the E2-related site 5'-TTCCCGCC- 3' and mediating repression of G1/S-regulated genes (By similarity). Acts as a promoter of spro [...] (917 aa)
foxaForkhead box A sequence. (355 aa)
psmd12Proteasome (Prosome, macropain) 26S subunit, non-ATPase, 12. (456 aa)
eif3eaEukaryotic translation initiation factor 3 subunit E-A; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. (446 aa)
ascc3Activating signal cointegrator 1 complex subunit 3; 3'-5' DNA helicase involved in repair of alkylated DNA. Promotes DNA unwinding to generate single-stranded substrate needed for alkbh3, enabling alkbh3 to process alkylated N3-methylcytosine (3mC) within double-stranded regions. (2025 aa)
foxj1bForkhead box protein J1-B; Key transcription factor required for motile ciliogenesis. Activates genes essential for motile cilia formation and function. Belongs to the FOXJ1 family. (442 aa)
foxo6bForkhead box O6 b. (714 aa)
foxd3Forkhead box D3. (371 aa)
elf1E74-like ETS transcription factor 1. (639 aa)
foxp1aForkhead box P1a. (637 aa)
si:dkey-7e14.3Si:dkey-7e14.3. (220 aa)
etv5aETS variant transcription factor 5a. (524 aa)
F2Z4R0_DANRESi:ch211-265o23.1. (536 aa)
foxb1aFork head domain protein FKD3. (297 aa)
cul5bCullin 5b; Belongs to the cullin family. (795 aa)
cul1aCullin 1a; Belongs to the cullin family. (777 aa)
metap2aMethionine aminopeptidase 2; Cotranslationally removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met- Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Belongs to the peptidase M24A family. Methionine aminopeptidase eukaryotic type 2 subfamily. (468 aa)
e2f3E2F transcription factor 3. (429 aa)
E7F8J2_DANRESi:dkey-108k21.10. (206 aa)
A2CEM5_DANRESi:ch211-145o7.3. (332 aa)
gpr155aG protein-coupled receptor 155a. (814 aa)
cul3bCullin 3b; Belongs to the cullin family. (766 aa)
ets2V-ets avian erythroblastosis virus E26 oncogene homolog 2. (439 aa)
hsf5Heat shock transcription factor family member 5. (416 aa)
etv1ETS variant transcription factor 1. (476 aa)
psmd11a26S proteasome non-ATPase regulatory subunit 11A; Component of the lid subcomplex of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. In the complex, psmd11a is required for proteasome assembly (By similarity). (421 aa)
shprhSNF2 histone linker PHD RING helicase. (1644 aa)
R4GEY3_DANRESi:ch211-113a14.18. (199 aa)
vps25Vacuolar protein-sorting-associated protein 25; Component of the ESCRT-II complex (endosomal sorting complex required for transport II), which is required for multivesicular body (MVB) formation and sorting of endosomal cargo proteins into MVBs. The MVB pathway mediates delivery of transmembrane proteins into the lumen of the lysosome for degradation. The ESCRT-II complex is probably involved in the recruitment of the ESCRT-III complex (By similarity). (174 aa)
irf3Interferon regulatory factor 3. (426 aa)
foxn3Forkhead box N3. (441 aa)
pikfyvePhosphatidylinositol phosphate 5-kinase type III isoform d. (2075 aa)
rfx5Regulatory factor X, 5. (590 aa)
cul4bCullin 4B; Belongs to the cullin family. (864 aa)
elk3ETS transcription factor ELK3. (408 aa)
irf9Interferon regulatory factor 9. (428 aa)
cul2Cullin 2; Belongs to the cullin family. (745 aa)
E9QFU6_DANRESi:ch73-36p18.1. (204 aa)
rad21bRAD21 cohesin complex component b. (637 aa)
hsf1Heat shock transcription factor 1. (523 aa)
LOC100332095La ribonucleoprotein 4Aa. (787 aa)
rgs6Regulator of G protein-signaling 6. (489 aa)
rgs9bRegulator of G protein-signaling 9b. (661 aa)
e2f7Transcription factor E2F7; Atypical E2F transcription factor that participates in various processes such as angiogenesis and polyploidization of specialized cells. Mainly acts as a transcription repressor that binds DNA independently of DP proteins and specifically recognizes the E2 recognition site 5'-TTTC[CG]CGC-3'. Directly represses transcription of classical E2F transcription factors such as e2f1. Acts as a regulator of S-phase by recognizing and binding the E2-related site 5'-TTCCCGCC- 3' and mediating repression of G1/S-regulated genes (By similarity). Acts as a promoter of spro [...] (723 aa)
foxd2Forkhead box D2. (369 aa)
rfx6DNA-binding protein RFX6; Transcription factor required to direct islet cell differentiation during endocrine pancreas development. Belongs to the RFX family. (907 aa)
erfEts2 repressor factor. (616 aa)
irf2aInterferon regulatory factor. (341 aa)
foxg1cForkhead box G1c. (379 aa)
si:rp71-45k5.2Si:rp71-45k5.2. (255 aa)
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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