| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| cd28 | foxp3a | ENSDARP00000115721 | ENSDARP00000080214 | CD28 molecule. | Forkhead box protein. | 0.774 |
| cd28 | il10 | ENSDARP00000115721 | ENSDARP00000098423 | CD28 molecule. | Interleukin-10. | 0.752 |
| cd28 | il6 | ENSDARP00000115721 | ENSDARP00000131017 | CD28 molecule. | Interleukin 6 (interferon, beta 2). | 0.543 |
| cnbpa | map3k7 | ENSDARP00000067292 | ENSDARP00000006286 | CCHC-type zinc finger, nucleic acid-binding protein a. | Mitogen-activated protein kinase kinase kinase 7. | 0.405 |
| cnbpb | map3k7 | ENSDARP00000095293 | ENSDARP00000006286 | CCHC-type zinc finger, nucleic acid-binding protein b. | Mitogen-activated protein kinase kinase kinase 7. | 0.402 |
| ctnnb1 | foxp3a | ENSDARP00000139205 | ENSDARP00000080214 | Catenin beta-1; Key downstream component of the canonical Wnt signaling pathway (By similarity). In the absence of Wnt, forms a complex with axin1, axin2, apc, csnk1a1 and gsk3b that promotes phosphorylation on N-terminal Ser and Thr residues and ubiquitination of ctnnb1 and its subsequent degradation by the proteasome (By similarity). In the presence of Wnt ligand, ctnnb1 is not ubiquitinated and accumulates in the nucleus, where it acts as a coactivator for transcription factors of the TCF/LEF family, leading to activate Wnt responsive genes (By similarity). Plays a key role in dorso [...] | Forkhead box protein. | 0.400 |
| ctnnb1 | il10 | ENSDARP00000139205 | ENSDARP00000098423 | Catenin beta-1; Key downstream component of the canonical Wnt signaling pathway (By similarity). In the absence of Wnt, forms a complex with axin1, axin2, apc, csnk1a1 and gsk3b that promotes phosphorylation on N-terminal Ser and Thr residues and ubiquitination of ctnnb1 and its subsequent degradation by the proteasome (By similarity). In the presence of Wnt ligand, ctnnb1 is not ubiquitinated and accumulates in the nucleus, where it acts as a coactivator for transcription factors of the TCF/LEF family, leading to activate Wnt responsive genes (By similarity). Plays a key role in dorso [...] | Interleukin-10. | 0.571 |
| ctnnb1 | rel | ENSDARP00000139205 | ENSDARP00000072078 | Catenin beta-1; Key downstream component of the canonical Wnt signaling pathway (By similarity). In the absence of Wnt, forms a complex with axin1, axin2, apc, csnk1a1 and gsk3b that promotes phosphorylation on N-terminal Ser and Thr residues and ubiquitination of ctnnb1 and its subsequent degradation by the proteasome (By similarity). In the presence of Wnt ligand, ctnnb1 is not ubiquitinated and accumulates in the nucleus, where it acts as a coactivator for transcription factors of the TCF/LEF family, leading to activate Wnt responsive genes (By similarity). Plays a key role in dorso [...] | V-rel avian reticuloendotheliosis viral oncogene homolog. | 0.431 |
| ctnnb1 | rela | ENSDARP00000139205 | ENSDARP00000133181 | Catenin beta-1; Key downstream component of the canonical Wnt signaling pathway (By similarity). In the absence of Wnt, forms a complex with axin1, axin2, apc, csnk1a1 and gsk3b that promotes phosphorylation on N-terminal Ser and Thr residues and ubiquitination of ctnnb1 and its subsequent degradation by the proteasome (By similarity). In the presence of Wnt ligand, ctnnb1 is not ubiquitinated and accumulates in the nucleus, where it acts as a coactivator for transcription factors of the TCF/LEF family, leading to activate Wnt responsive genes (By similarity). Plays a key role in dorso [...] | V-rel avian reticuloendotheliosis viral oncogene homolog A. | 0.505 |
| ctnnb1 | wnt5a | ENSDARP00000139205 | ENSDARP00000137200 | Catenin beta-1; Key downstream component of the canonical Wnt signaling pathway (By similarity). In the absence of Wnt, forms a complex with axin1, axin2, apc, csnk1a1 and gsk3b that promotes phosphorylation on N-terminal Ser and Thr residues and ubiquitination of ctnnb1 and its subsequent degradation by the proteasome (By similarity). In the presence of Wnt ligand, ctnnb1 is not ubiquitinated and accumulates in the nucleus, where it acts as a coactivator for transcription factors of the TCF/LEF family, leading to activate Wnt responsive genes (By similarity). Plays a key role in dorso [...] | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. | 0.944 |
| ctnnb1 | wnt5b | ENSDARP00000139205 | ENSDARP00000134193 | Catenin beta-1; Key downstream component of the canonical Wnt signaling pathway (By similarity). In the absence of Wnt, forms a complex with axin1, axin2, apc, csnk1a1 and gsk3b that promotes phosphorylation on N-terminal Ser and Thr residues and ubiquitination of ctnnb1 and its subsequent degradation by the proteasome (By similarity). In the presence of Wnt ligand, ctnnb1 is not ubiquitinated and accumulates in the nucleus, where it acts as a coactivator for transcription factors of the TCF/LEF family, leading to activate Wnt responsive genes (By similarity). Plays a key role in dorso [...] | Protein Wnt-5b; Ligand for members of the frizzled family of seven transmembrane receptors. Can activate or inhibit canonical Wnt signaling, depending on receptor context. Required during embryogenesis for extension of the primary anterior-posterior axis. | 0.960 |
| foxp3a | cd28 | ENSDARP00000080214 | ENSDARP00000115721 | Forkhead box protein. | CD28 molecule. | 0.774 |
| foxp3a | ctnnb1 | ENSDARP00000080214 | ENSDARP00000139205 | Forkhead box protein. | Catenin beta-1; Key downstream component of the canonical Wnt signaling pathway (By similarity). In the absence of Wnt, forms a complex with axin1, axin2, apc, csnk1a1 and gsk3b that promotes phosphorylation on N-terminal Ser and Thr residues and ubiquitination of ctnnb1 and its subsequent degradation by the proteasome (By similarity). In the presence of Wnt ligand, ctnnb1 is not ubiquitinated and accumulates in the nucleus, where it acts as a coactivator for transcription factors of the TCF/LEF family, leading to activate Wnt responsive genes (By similarity). Plays a key role in dorso [...] | 0.400 |
| foxp3a | il10 | ENSDARP00000080214 | ENSDARP00000098423 | Forkhead box protein. | Interleukin-10. | 0.958 |
| foxp3a | il6 | ENSDARP00000080214 | ENSDARP00000131017 | Forkhead box protein. | Interleukin 6 (interferon, beta 2). | 0.453 |
| foxp3a | myd88 | ENSDARP00000080214 | ENSDARP00000020711 | Forkhead box protein. | Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and Il-1 receptor signaling pathway in the innate immune response. | 0.585 |
| foxp3a | rel | ENSDARP00000080214 | ENSDARP00000072078 | Forkhead box protein. | V-rel avian reticuloendotheliosis viral oncogene homolog. | 0.518 |
| il10 | cd28 | ENSDARP00000098423 | ENSDARP00000115721 | Interleukin-10. | CD28 molecule. | 0.752 |
| il10 | ctnnb1 | ENSDARP00000098423 | ENSDARP00000139205 | Interleukin-10. | Catenin beta-1; Key downstream component of the canonical Wnt signaling pathway (By similarity). In the absence of Wnt, forms a complex with axin1, axin2, apc, csnk1a1 and gsk3b that promotes phosphorylation on N-terminal Ser and Thr residues and ubiquitination of ctnnb1 and its subsequent degradation by the proteasome (By similarity). In the presence of Wnt ligand, ctnnb1 is not ubiquitinated and accumulates in the nucleus, where it acts as a coactivator for transcription factors of the TCF/LEF family, leading to activate Wnt responsive genes (By similarity). Plays a key role in dorso [...] | 0.571 |
| il10 | foxp3a | ENSDARP00000098423 | ENSDARP00000080214 | Interleukin-10. | Forkhead box protein. | 0.958 |