STRINGSTRING
ralba ralba casp3a casp3a tnfb tnfb chuk chuk ripk1l ripk1l stat1a stat1a myd88 myd88 insra insra ifnphi1 ifnphi1 traf6 traf6 ucp1 ucp1 braf braf stat2 stat2 ins ins ralaa ralaa casp3b casp3b rel rel mavs mavs irf7 irf7 stat3 stat3 insrb insrb tet2 tet2 rabif rabif plin2 plin2 gcgb gcgb ulk1b ulk1b insb insb g6pca.1 g6pca.1 lipea lipea dio2 dio2 bcl2a bcl2a irf9 irf9 cylda cylda exoc5 exoc5 irf3 irf3 relb relb exoc3l2b exoc3l2b gli1 gli1 rela rela tank tank lipeb lipeb ccnd1 ccnd1 fgf21 fgf21 pde3b pde3b plin3 plin3 kras kras
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ralbaV-ral simian leukemia viral oncogene homolog Ba (ras-related). (207 aa)
casp3aCaspase 3, apoptosis-related cysteine peptidase a; Belongs to the peptidase C14A family. (282 aa)
tnfbTumor necrosis factor b (TNF superfamily, member 2). (242 aa)
chukInhibitor of nuclear factor kappa-B kinase subunit alpha; Phosphorylates inhibitors of NF-kappa-B thus leading to the dissociation of the inhibitor/NF-kappa-B complex and ultimately the degradation of the inhibitor. Phosphorylates 'Ser-10' of histone H3 at NF-kappa-B-regulated promoters during inflammatory responses triggered by cytokines; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. I-kappa-B kinase subfamily. (758 aa)
ripk1lReceptor (TNFRSF)-interacting serine-threonine kinase 1,-like. (661 aa)
stat1aSignal transducer and activator of transcription. (749 aa)
myd88Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and Il-1 receptor signaling pathway in the innate immune response. (284 aa)
insraTyrosine-protein kinase receptor. (1353 aa)
ifnphi1Interferon phi 1. (185 aa)
traf6TNF receptor-associated factor 6; E3 ubiquitin-protein ligase that mediates ubiquitination of proteins. Adapter protein that seems to play a role in signal transduction. (542 aa)
ucp1Uncoupling protein 1; Belongs to the mitochondrial carrier (TC 2.A.29) family. (309 aa)
brafB-Raf proto-oncogene, serine/threonine kinase. (817 aa)
stat2Signal transducer and activator of transcription. (836 aa)
insInsulin A chain; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (108 aa)
ralaaV-ral simian leukemia viral oncogene homolog Aa (ras-related). (206 aa)
casp3bCaspase 3, apoptosis-related cysteine peptidase b; Belongs to the peptidase C14A family. (285 aa)
relV-rel avian reticuloendotheliosis viral oncogene homolog. (596 aa)
mavsMitochondrial antiviral-signaling protein. (364 aa)
irf7Interferon regulatory factor 7. (422 aa)
stat3Signal transducer and activator of transcription. (806 aa)
insrbTyrosine-protein kinase receptor. (1348 aa)
tet2Tet methylcytosine dioxygenase 2. (1715 aa)
rabifRAB-interacting factor. (132 aa)
plin2Perilipin; Belongs to the perilipin family. (444 aa)
gcgbGlucagon b. (124 aa)
ulk1bUnc-51-like autophagy-activating kinase 1. (1011 aa)
insbInsulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (159 aa)
g6pca.1Glucose-6-phosphatase; Belongs to the glucose-6-phosphatase family. (352 aa)
lipeaLipase, hormone-sensitive a. (696 aa)
dio2Iodothyronine deiodinase; Responsible for the deiodination of T4 (3,5,3',5'- tetraiodothyronine). (258 aa)
bcl2aB-cell leukemia/lymphoma 2. (228 aa)
irf9Interferon regulatory factor 9. (428 aa)
cyldaCylindromatosis (turban tumor syndrome), a; Belongs to the peptidase C19 family. (951 aa)
exoc5Exocyst complex component 5. (708 aa)
irf3Interferon regulatory factor 3. (426 aa)
relbV-rel avian reticuloendotheliosis viral oncogene homolog B. (582 aa)
exoc3l2bExocyst complex component 3-like 2b. (861 aa)
gli1GLI family zinc finger 1. (1404 aa)
relaV-rel avian reticuloendotheliosis viral oncogene homolog A. (455 aa)
tankTRAF family member-associated NFKB activator. (348 aa)
lipebLipase, hormone-sensitive b. (872 aa)
ccnd1G1/S-specific cyclin-D1; May play a role in transcriptional regulation (By similarity). Essential for the control of the cell cycle at the G1/S (start) transition. (291 aa)
fgf21Fibroblast growth factor 21; Belongs to the heparin-binding growth factors family. (194 aa)
pde3bPhosphodiesterase. (1103 aa)
plin3Perilipin; Belongs to the perilipin family. (432 aa)
krasV-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog. (189 aa)
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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