STRINGSTRING
tcea1 tcea1 rpa1 rpa1 usp40 usp40 uba52 uba52 phf3 phf3 kxd1 kxd1 ddb1 ddb1 xab2 xab2 aqr aqr ercc2 ercc2 pole4 pole4 LOC108271213 LOC108271213 pole3 pole3 ercc8 ercc8 polr2c polr2c bivm bivm ercc5 ercc5 tcea2 tcea2 rfc3 rfc3 gtf2h1 gtf2h1 cul4a cul4a znf830 znf830 polr2k polr2k polr2d polr2d LOC108254962 LOC108254962 LOC108272412 LOC108272412 rfc4 rfc4 ercc1 ercc1 polk polk prpf19 prpf19 tceanc2 tceanc2 ccnh ccnh tceanc tceanc pold4 pold4 usp7 usp7 rpa2 rpa2 rps27a rps27a polr2b polr2b gtf2h4 gtf2h4 atad5 atad5 nrde2 nrde2 ENSIPUP00000024509 ENSIPUP00000024509 ENSIPUP00000024519 ENSIPUP00000024519 rfc2 rfc2 pcna pcna polr2h polr2h polr2j polr2j pold1 pold1 gtf2h2c gtf2h2c rbx1 rbx1 LOC108272975 LOC108272975 LOC108273255 LOC108273255 LOC108279000 LOC108279000 rcbtb2 rcbtb2 ercc3 ercc3 LOC108277308 LOC108277308 rcbtb1 rcbtb1 gtf2h3 gtf2h3 pole pole rfc5 rfc5 polr2e polr2e gtf2h5 gtf2h5 cdk7 cdk7 cul4b cul4b LOC108260037 LOC108260037 polr2l polr2l rpa3 rpa3 ENSIPUP00000024949 ENSIPUP00000024949 uvssa uvssa pole2 pole2 ppie ppie ercc6 ercc6 polr2g polr2g polr2f polr2f LOC108273944 LOC108273944 polr2i polr2i ercc4 ercc4 meiob meiob pold3 pold3 pold2 pold2 polr2a polr2a mnat1 mnat1 rfc1 rfc1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
tcea1Transcription elongation factor A protein 1 isoform X1. (308 aa)
rpa1Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (606 aa)
usp40LOW QUALITY PROTEIN: ubiquitin carboxyl-terminal hydrolase 40; Belongs to the peptidase C19 family. (92 aa)
uba52ubiquitin-60S ribosomal protein L40 isoform X1. (128 aa)
phf3PHD finger protein 3. (1688 aa)
kxd1kxDL motif-containing protein 1 isoform X2. (187 aa)
ddb1DNA damage-binding protein 1. (1140 aa)
xab2Pre-mRNA-splicing factor SYF1. (849 aa)
aqrIntron-binding protein aquarius isoform X1. (1485 aa)
ercc2TFIIH basal transcription factor complex helicase XPD subunit isoform X1. (761 aa)
pole4DNA polymerase epsilon subunit 4. (125 aa)
LOC108271213C-C motif chemokine 20-like. (127 aa)
pole3DNA polymerase epsilon subunit 3. (149 aa)
ercc8DNA excision repair protein ERCC-8. (397 aa)
polr2cDNA-directed RNA polymerase II subunit RPB3 isoform X1. (275 aa)
bivmBasic immunoglobulin-like variable motif-containing protein isoform X1. (504 aa)
ercc5DNA repair protein complementing XP-G cells. (1107 aa)
tcea2Transcription elongation factor A protein 2. (305 aa)
rfc3Replication factor C subunit 3. (356 aa)
gtf2h1General transcription factor IIH subunit 1. (549 aa)
cul4acullin-4A; Belongs to the cullin family. (741 aa)
znf830Zinc finger protein 830. (333 aa)
polr2kDNA-directed RNA polymerases I, II, and III subunit RPABC4. (68 aa)
polr2dDNA-directed RNA polymerase II subunit RPB4. (141 aa)
LOC108254962pre-mRNA-splicing factor ISY1 homolog. (284 aa)
LOC108272412Replication protein A 32 kDa subunit-like. (251 aa)
rfc4Replication factor C subunit 4 isoform X1. (358 aa)
ercc1DNA excision repair protein ERCC-1. (367 aa)
polkDNA polymerase kappa. (927 aa)
prpf19pre-mRNA-processing factor 19. (507 aa)
tceanc2Transcription elongation factor A N-terminal and central domain-containing protein 2. (211 aa)
ccnhCyclin-H; Belongs to the cyclin family. (321 aa)
tceancTranscription elongation factor A N-terminal and central domain-containing protein. (351 aa)
pold4DNA polymerase delta subunit 4. (109 aa)
usp7Ubiquitin carboxyl-terminal hydrolase 7 isoform X1; Belongs to the peptidase C19 family. (1112 aa)
rpa2Replication protein A 32 kDa subunit. (294 aa)
rps27aUbiquitin-40S ribosomal protein S27a; Ubiquitin exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-6-linked may be invo [...] (156 aa)
polr2bDNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1174 aa)
gtf2h4General transcription factor IIH subunit 4; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family. (467 aa)
atad5ATPase family AAA domain-containing protein 5 isoform X1. (1798 aa)
nrde2Protein NRDE2 homolog. (1116 aa)
ENSIPUP00000024509Peptidylprolyl isomerase E (cyclophilin E). (154 aa)
ENSIPUP00000024519annotation not available (106 aa)
rfc2Replication factor C subunit 2. (357 aa)
pcnaProliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (297 aa)
polr2hDNA-directed RNA polymerases I, II, and III subunit RPABC3; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non- coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively. (150 aa)
polr2jDNA-directed RNA polymerase II subunit RPB11-a. (117 aa)
pold1DNA polymerase. (1066 aa)
gtf2h2cGeneral transcription factor IIH subunit 2-like protein. (394 aa)
rbx1E3 ubiquitin-protein ligase RBX1. (108 aa)
LOC108272975Histone acetyltransferase p300-like isoform X2. (2494 aa)
LOC108273255ATPase family AAA domain-containing protein 5-like. (927 aa)
LOC108279000E3 ubiquitin-protein ligase RBX1-like. (108 aa)
rcbtb2RCC1 and BTB domain-containing protein 2. (540 aa)
ercc3TFIIH basal transcription factor complex helicase XPB subunit. (780 aa)
LOC108277308Non-histone chromosomal protein HMG-14A-like. (90 aa)
rcbtb1RCC1 and BTB domain-containing protein 1. (531 aa)
gtf2h3General transcription factor IIH subunit 3 isoform X1. (300 aa)
poleDNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (2286 aa)
rfc5Replication factor C subunit 5. (339 aa)
polr2eDNA-directed RNA polymerases I, II, and III subunit RPABC1 isoform X1. (210 aa)
gtf2h5General transcription factor IIH subunit 5 isoform X1. (71 aa)
cdk7Cell division protein kinase 7; Belongs to the protein kinase superfamily. (345 aa)
cul4bcullin-4B; Belongs to the cullin family. (854 aa)
LOC108260037Non-histone chromosomal protein HMG-14A-like. (95 aa)
polr2lDNA-directed RNA polymerases i II and III subunit rpabc5. (67 aa)
rpa3Replication protein A 14 kDa subunit. (122 aa)
ENSIPUP00000024949Transcription elongation factor A (SII), 3. (368 aa)
uvssaUV-stimulated scaffold protein A. (732 aa)
pole2DNA polymerase epsilon subunit; Participates in DNA repair and in chromosomal DNA replication; Belongs to the DNA polymerase epsilon subunit B family. (528 aa)
ppiePeptidyl-prolyl cis-trans isomerase E; Catalyzes the cis-trans isomerization of proline imidic peptide bonds in proteins; Belongs to the cyclophilin-type PPIase family. PPIase E subfamily. (302 aa)
ercc6DNA excision repair protein ERCC-6. (1409 aa)
polr2gDNA-directed RNA polymerase II subunit RPB7. (172 aa)
polr2fDNA-directed RNA polymerases I, II, and III subunit RPABC2. (97 aa)
LOC108273944Histone acetyltransferase p300-like isoform X6. (2631 aa)
polr2iDNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family. (135 aa)
ercc4DNA repair endonuclease XPF. (899 aa)
meiobMeiosis-specific with OB domain-containing protein. (466 aa)
pold3DNA polymerase delta subunit 3 isoform X1. (471 aa)
pold2DNA polymerase delta subunit 2. (467 aa)
polr2aDNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1966 aa)
mnat1CDK-activating kinase assembly factor MAT1; Stabilizes the cyclin H-CDK7 complex to form a functional CDK-activating kinase (CAK) enzymatic complex. (310 aa)
rfc1Replication factor C subunit 1. (1129 aa)
Your Current Organism:
Ictalurus punctatus
NCBI taxonomy Id: 7998
Other names: I. punctatus, Silurus punctatus, channel catfish
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