20 items (Electrophorus electricus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	dcp2	Nudix hydrolase domain-containing protein. (398 aa)
	DXO	RAI1 domain-containing protein. (416 aa)
	dclre1c	DNA cross-link repair 1C, PSO2 homolog (S. cerevisiae). (683 aa)
	aptx	HIT domain-containing protein. (381 aa)
	dclre1a	DNA cross-link repair 1A (PSO2 homolog, S. cerevisiae). (951 aa)
	dclre1b	DNA cross-link repair 1B. (580 aa)
	xrn2	5'-3' exoribonuclease; Possesses 5'->3' exoribonuclease activity. May promote termination of transcription by RNA polymerase II. (972 aa)
	exo1	Exonuclease 1. (771 aa)
	cpsf3	Uncharacterized protein. (691 aa)
	mre11	Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing. (667 aa)
	pld3	Uncharacterized protein. (494 aa)
	LOC113573356	Si:dkeyp-110e4.6. (527 aa)
	fen1	Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] (380 aa)
	xrn1	5'-3' exoribonuclease 1. (1689 aa)
	LOC113590030	Uncharacterized protein. (347 aa)
	PLD4	Uncharacterized protein. (504 aa)
	fan1	Fanconi-associated nuclease; Nuclease required for the repair of DNA interstrand cross- links (ICL). Acts as a 5'-3' exonuclease that anchors at a cut end of DNA and cleaves DNA successively at every third nucleotide, allowing to excise an ICL from one strand through flanking incisions. Belongs to the FAN1 family. (1005 aa)
	Trir	Telomerase RNA component interacting RNase. (153 aa)
	ENSEEEP00000050839	Metallophos domain-containing protein. (106 aa)
	exo5	Uncharacterized protein. (392 aa)

Your Current Organism:

Electrophorus electricus

NCBI taxonomy Id: 8005
Other names: E. electricus, electric eel, electric knifefish

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DXO	dcp2	ENSEEEP00000007714	ENSEEEP00000043019	RAI1 domain-containing protein.	Nudix hydrolase domain-containing protein.	0.615
DXO	exo1	ENSEEEP00000007714	ENSEEEP00000019719	RAI1 domain-containing protein.	Exonuclease 1.	0.438
DXO	xrn1	ENSEEEP00000007714	ENSEEEP00000033042	RAI1 domain-containing protein.	5'-3' exoribonuclease 1.	0.642
DXO	xrn2	ENSEEEP00000007714	ENSEEEP00000019609	RAI1 domain-containing protein.	5'-3' exoribonuclease; Possesses 5'->3' exoribonuclease activity. May promote termination of transcription by RNA polymerase II.	0.993
ENSEEEP00000050839	LOC113590030	ENSEEEP00000050839	ENSEEEP00000033260	Metallophos domain-containing protein.	Uncharacterized protein.	0.889
ENSEEEP00000050839	cpsf3	ENSEEEP00000050839	ENSEEEP00000020892	Metallophos domain-containing protein.	Uncharacterized protein.	0.516
ENSEEEP00000050839	dclre1a	ENSEEEP00000050839	ENSEEEP00000012300	Metallophos domain-containing protein.	DNA cross-link repair 1A (PSO2 homolog, S. cerevisiae).	0.665
ENSEEEP00000050839	dclre1b	ENSEEEP00000050839	ENSEEEP00000016650	Metallophos domain-containing protein.	DNA cross-link repair 1B.	0.654
ENSEEEP00000050839	dclre1c	ENSEEEP00000050839	ENSEEEP00000008266	Metallophos domain-containing protein.	DNA cross-link repair 1C, PSO2 homolog (S. cerevisiae).	0.705
ENSEEEP00000050839	exo1	ENSEEEP00000050839	ENSEEEP00000019719	Metallophos domain-containing protein.	Exonuclease 1.	0.960
ENSEEEP00000050839	fen1	ENSEEEP00000050839	ENSEEEP00000032875	Metallophos domain-containing protein.	Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...]	0.889
LOC113590030	ENSEEEP00000050839	ENSEEEP00000033260	ENSEEEP00000050839	Uncharacterized protein.	Metallophos domain-containing protein.	0.889
LOC113590030	aptx	ENSEEEP00000033260	ENSEEEP00000008552	Uncharacterized protein.	HIT domain-containing protein.	0.500
LOC113590030	exo1	ENSEEEP00000033260	ENSEEEP00000019719	Uncharacterized protein.	Exonuclease 1.	0.836
LOC113590030	fen1	ENSEEEP00000033260	ENSEEEP00000032875	Uncharacterized protein.	Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...]	0.905
LOC113590030	mre11	ENSEEEP00000033260	ENSEEEP00000024860	Uncharacterized protein.	Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing.	0.889
PLD4	pld3	ENSEEEP00000045459	ENSEEEP00000026951	Uncharacterized protein.	Uncharacterized protein.	0.904
aptx	LOC113590030	ENSEEEP00000008552	ENSEEEP00000033260	HIT domain-containing protein.	Uncharacterized protein.	0.500
aptx	exo1	ENSEEEP00000008552	ENSEEEP00000019719	HIT domain-containing protein.	Exonuclease 1.	0.612
aptx	fen1	ENSEEEP00000008552	ENSEEEP00000032875	HIT domain-containing protein.	Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...]	0.500